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The map label for this gene is alaT [H]

Identifier: 52787017

GI number: 52787017

Start: 3179818

End: 3180990

Strand: Reverse

Name: alaT [H]

Synonym: BLi03320

Alternate gene names: 52787017

Gene position: 3180990-3179818 (Counterclockwise)

Preceding gene: 52787018

Following gene: 52787016

Centisome position: 75.33

GC content: 49.79

Gene sequence:

>1173_bases
ATGAGGACAACTTATATTTCAAAAGCAGCCCAGCAGATCAAACCGTCAGGCATCCGCAAATTTTTTGATCTTGCGTCCAC
AATGGAGGGCGTGATTTCATTGGGAGTCGGAGAGCCAGATTTTGTGACGGCGTGGAATGTAAGGGAAGCGAGCATCCTTT
CCCTTGAGCAGGGCTACACGTCTTATACGGCAAACGCGGGTCTTCTTTCTCTGCGGAAAGAGATCAGCGCTTATCTGAAT
AAACGTTTTCATCTGGATTATGCTCCTGATGACGAGCTGATTGTTACAGTCGGAGCAAGCCAGGCGCTTGATATTGCGGT
CAGGGCGATCCTTGATCCCGGAGAAGAAGTGCTGATTCCTGAGCCTTGTTTTGTCGCTTATGAAGCGCTTGTCTCTTTGG
CGGGGGGAAAAGCGGTCCACATTCATACGAACGCAGAGCGCGGATTTAAAGCGAGCGCTGCAGATTTTGAAGCCGTTCTG
ACTGAGCGTACGAAGGCCATCATTCTTTGCACCCCGTCTAATCCGACAGGCTCTGTTTATTCAAAAAAAGAACTGGAAGA
GATCGCGGCTTTTGCCGAAAAACACGACCTGATTGTAATAGCGGATGAAATTTACGCCGAGCTGACATACGATGAAGCGT
ATACAAGCTTTGCGGAAATCGCCGGAATGAAAAAGCGGACGATATTGATATCGGGTTTTTCTAAAGGGTTTGCCATGACA
GGCTGGCGCCTCGGATATGTCGCAGCTCCTGCATATTTAAGGGACCCTATGCTGAAAATTCACCAGTACTCGATGATGTG
CGCGCCAAGCATGGCTCAATTTGCGGCGGAGGAAGCCCTTAAAAACGGCCTCGAAGACGTTGAAAAGATGAAAAAAAGCT
ACCGCCGCCGAAGAAACGTGTTTGTGGATTCACTGAACGAAATCGGGCTTGACTGCCATCAGCCGGGGGGCGCTTTTTAC
GCGTTTCCATCCGTTAAAAAAACGGGCATGAGCTCAGAGCAGTTTGCAGAGGAGCTGCTCATCAGCGAAAAAGTCGCCGT
CGTCCCGGGCAATGTTTTCGGTCCGAGCGGCGAGGGCTATATCAGATGTTCCTATGCTTCCTCGCTTGAACAGCTTCAGG
AAGCACTCGTCAGAATGAAGCGCTTTGTGGAGAAGGTCGGTGCAGTAAAATAA

Upstream 100 bases:

>100_bases
CGTGTCGACAACCACCCACTTTATTTTAAAGAAATACAAGCATGACGGTAAAGTTTTTGACTCCGGTGATGATGACAAAA
GAATCGTGGTGTCTCCTTAA

Downstream 100 bases:

>100_bases
AAAAATGCGCACCTGAAAGGTCCGCATCAACATAAGGGGGGAATACTAGAAAGCCTTAGTTGTTCTTTAGTATTCCCCTT
TCAACTCGGTTTTAAACATA

Product: hypothetical protein

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRTTYISKAAQQIKPSGIRKFFDLASTMEGVISLGVGEPDFVTAWNVREASILSLEQGYTSYTANAGLLSLRKEISAYLN
KRFHLDYAPDDELIVTVGASQALDIAVRAILDPGEEVLIPEPCFVAYEALVSLAGGKAVHIHTNAERGFKASAADFEAVL
TERTKAIILCTPSNPTGSVYSKKELEEIAAFAEKHDLIVIADEIYAELTYDEAYTSFAEIAGMKKRTILISGFSKGFAMT
GWRLGYVAAPAYLRDPMLKIHQYSMMCAPSMAQFAAEEALKNGLEDVEKMKKSYRRRRNVFVDSLNEIGLDCHQPGGAFY
AFPSVKKTGMSSEQFAEELLISEKVAVVPGNVFGPSGEGYIRCSYASSLEQLQEALVRMKRFVEKVGAVK

Sequences:

>Translated_390_residues
MRTTYISKAAQQIKPSGIRKFFDLASTMEGVISLGVGEPDFVTAWNVREASILSLEQGYTSYTANAGLLSLRKEISAYLN
KRFHLDYAPDDELIVTVGASQALDIAVRAILDPGEEVLIPEPCFVAYEALVSLAGGKAVHIHTNAERGFKASAADFEAVL
TERTKAIILCTPSNPTGSVYSKKELEEIAAFAEKHDLIVIADEIYAELTYDEAYTSFAEIAGMKKRTILISGFSKGFAMT
GWRLGYVAAPAYLRDPMLKIHQYSMMCAPSMAQFAAEEALKNGLEDVEKMKKSYRRRRNVFVDSLNEIGLDCHQPGGAFY
AFPSVKKTGMSSEQFAEELLISEKVAVVPGNVFGPSGEGYIRCSYASSLEQLQEALVRMKRFVEKVGAVK
>Mature_390_residues
MRTTYISKAAQQIKPSGIRKFFDLASTMEGVISLGVGEPDFVTAWNVREASILSLEQGYTSYTANAGLLSLRKEISAYLN
KRFHLDYAPDDELIVTVGASQALDIAVRAILDPGEEVLIPEPCFVAYEALVSLAGGKAVHIHTNAERGFKASAADFEAVL
TERTKAIILCTPSNPTGSVYSKKELEEIAAFAEKHDLIVIADEIYAELTYDEAYTSFAEIAGMKKRTILISGFSKGFAMT
GWRLGYVAAPAYLRDPMLKIHQYSMMCAPSMAQFAAEEALKNGLEDVEKMKKSYRRRRNVFVDSLNEIGLDCHQPGGAFY
AFPSVKKTGMSSEQFAEELLISEKVAVVPGNVFGPSGEGYIRCSYASSLEQLQEALVRMKRFVEKVGAVK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=321, Percent_Identity=30.8411214953271, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI169881279, Length=321, Percent_Identity=30.8411214953271, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI56713254, Length=317, Percent_Identity=31.8611987381703, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI56713256, Length=318, Percent_Identity=31.7610062893082, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI169881281, Length=222, Percent_Identity=31.0810810810811, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=26.2599469496021, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI187936925, Length=425, Percent_Identity=24, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI14211921, Length=425, Percent_Identity=24, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI19263340, Length=391, Percent_Identity=24.5524296675192, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI215599424, Length=391, Percent_Identity=24.5524296675192, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4885351, Length=373, Percent_Identity=26.2734584450402, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI149944424, Length=402, Percent_Identity=24.8756218905473, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786816, Length=355, Percent_Identity=27.3239436619718, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788627, Length=365, Percent_Identity=31.2328767123288, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=27.4725274725275, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790797, Length=342, Percent_Identity=25.1461988304094, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787909, Length=292, Percent_Identity=23.972602739726, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787710, Length=281, Percent_Identity=24.5551601423488, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=298, Percent_Identity=33.5570469798658, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71994476, Length=298, Percent_Identity=33.5570469798658, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=394, Percent_Identity=27.6649746192893, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=28.1081081081081, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71981209, Length=372, Percent_Identity=23.9247311827957, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=205, Percent_Identity=24.8780487804878, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=294, Percent_Identity=28.9115646258503, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=352, Percent_Identity=23.5795454545455, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=372, Percent_Identity=23.6559139784946, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=405, Percent_Identity=27.4074074074074, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24646114, Length=405, Percent_Identity=27.4074074074074, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28573067, Length=405, Percent_Identity=27.4074074074074, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28573065, Length=405, Percent_Identity=27.4074074074074, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=25.065274151436, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=26.5822784810127, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=26.5822784810127, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 42832; Mature: 42832

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTYISKAAQQIKPSGIRKFFDLASTMEGVISLGVGEPDFVTAWNVREASILSLEQGYT
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHEEHHCCCC
SYTANAGLLSLRKEISAYLNKRFHLDYAPDDELIVTVGASQALDIAVRAILDPGEEVLIP
CCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECC
EPCFVAYEALVSLAGGKAVHIHTNAERGFKASAADFEAVLTERTKAIILCTPSNPTGSVY
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
SKKELEEIAAFAEKHDLIVIADEIYAELTYDEAYTSFAEIAGMKKRTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEC
GWRLGYVAAPAYLRDPMLKIHQYSMMCAPSMAQFAAEEALKNGLEDVEKMKKSYRRRRNV
CEEEHHEECCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDSLNEIGLDCHQPGGAFYAFPSVKKTGMSSEQFAEELLISEKVAVVPGNVFGPSGEGY
HHHHHHHCCCCCCCCCCCEEECCCHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCE
IRCSYASSLEQLQEALVRMKRFVEKVGAVK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRTTYISKAAQQIKPSGIRKFFDLASTMEGVISLGVGEPDFVTAWNVREASILSLEQGYT
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHEEHHCCCC
SYTANAGLLSLRKEISAYLNKRFHLDYAPDDELIVTVGASQALDIAVRAILDPGEEVLIP
CCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECC
EPCFVAYEALVSLAGGKAVHIHTNAERGFKASAADFEAVLTERTKAIILCTPSNPTGSVY
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
SKKELEEIAAFAEKHDLIVIADEIYAELTYDEAYTSFAEIAGMKKRTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEC
GWRLGYVAAPAYLRDPMLKIHQYSMMCAPSMAQFAAEEALKNGLEDVEKMKKSYRRRRNV
CEEEHHEECCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDSLNEIGLDCHQPGGAFYAFPSVKKTGMSSEQFAEELLISEKVAVVPGNVFGPSGEGY
HHHHHHHCCCCCCCCCCCEEECCCHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCE
IRCSYASSLEQLQEALVRMKRFVEKVGAVK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]