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The map label for this gene is alaR [H]

Identifier: 52787018

GI number: 52787018

Start: 3180991

End: 3181491

Strand: Reverse

Name: alaR [H]

Synonym: BLi03321

Alternate gene names: 52787018

Gene position: 3181491-3180991 (Counterclockwise)

Preceding gene: 52787020

Following gene: 52787017

Centisome position: 75.34

GC content: 43.11

Gene sequence:

>501_bases
ATGAAGCTAACAGAAAAAGAAACAGAAATATTGGAAATATTAGAGGAAAACAGCCGCCTCGAACCTGAAACGATTGCTAA
AATGGCGAACATTTCACAGGAAGAAACAAAAGCGATTATTGAAAAGCTTGAAAAAGAAAAGGTCATCATCGATTATTCTG
CAATGATCGACTGGCGAAAAGTCGACGGCCATGAAGGCGTGACAGCGATGATCGATGTGAAAGTAACGCCGAAGCGCGGC
GTCGGATTTGACGAAGTGGCCGAGCGGATTTATCGTTTTCAGGAAGTTGAATCCGTTTACTTGATGTCAGGCGTATATGA
CCTGTCTGTTGTCATCCGCGGCAGAACGATGTCGGATATTTCGCATTTCGTGTCCGAAAAATTATCGACGCTTGAATCGG
TCGTGTCGACAACCACCCACTTTATTTTAAAGAAATACAAGCATGACGGTAAAGTTTTTGACTCCGGTGATGATGACAAA
AGAATCGTGGTGTCTCCTTAA

Upstream 100 bases:

>100_bases
TTCACGCTGCGATTTCGCTTTTTTTACCGCCTTACATTCGTATAAAAACGTGCTATAATATTCAGAAGATTTCTTGACAT
ATAAAAGGTGTGATAACGAG

Downstream 100 bases:

>100_bases
ATGAGGACAACTTATATTTCAAAAGCAGCCCAGCAGATCAAACCGTCAGGCATCCGCAAATTTTTTGATCTTGCGTCCAC
AATGGAGGGCGTGATTTCAT

Product: AlaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MKLTEKETEILEILEENSRLEPETIAKMANISQEETKAIIEKLEKEKVIIDYSAMIDWRKVDGHEGVTAMIDVKVTPKRG
VGFDEVAERIYRFQEVESVYLMSGVYDLSVVIRGRTMSDISHFVSEKLSTLESVVSTTTHFILKKYKHDGKVFDSGDDDK
RIVVSP

Sequences:

>Translated_166_residues
MKLTEKETEILEILEENSRLEPETIAKMANISQEETKAIIEKLEKEKVIIDYSAMIDWRKVDGHEGVTAMIDVKVTPKRG
VGFDEVAERIYRFQEVESVYLMSGVYDLSVVIRGRTMSDISHFVSEKLSTLESVVSTTTHFILKKYKHDGKVFDSGDDDK
RIVVSP
>Mature_166_residues
MKLTEKETEILEILEENSRLEPETIAKMANISQEETKAIIEKLEKEKVIIDYSAMIDWRKVDGHEGVTAMIDVKVTPKRG
VGFDEVAERIYRFQEVESVYLMSGVYDLSVVIRGRTMSDISHFVSEKLSTLESVVSTTTHFILKKYKHDGKVFDSGDDDK
RIVVSP

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18959; Mature: 18959

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTEKETEILEILEENSRLEPETIAKMANISQEETKAIIEKLEKEKVIIDYSAMIDWRK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHHHEEHHC
VDGHEGVTAMIDVKVTPKRGVGFDEVAERIYRFQEVESVYLMSGVYDLSVVIRGRTMSDI
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCHHHH
SHFVSEKLSTLESVVSTTTHFILKKYKHDGKVFDSGDDDKRIVVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEECC
>Mature Secondary Structure
MKLTEKETEILEILEENSRLEPETIAKMANISQEETKAIIEKLEKEKVIIDYSAMIDWRK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEHHHHEEHHC
VDGHEGVTAMIDVKVTPKRGVGFDEVAERIYRFQEVESVYLMSGVYDLSVVIRGRTMSDI
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHEEEEEEECCCHHHH
SHFVSEKLSTLESVVSTTTHFILKKYKHDGKVFDSGDDDKRIVVSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]