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The map label for this gene is fmt

Identifier: 52785553

GI number: 52785553

Start: 1752659

End: 1753609

Strand: Direct

Name: fmt

Synonym: BLi01794

Alternate gene names: 52785553

Gene position: 1752659-1753609 (Clockwise)

Preceding gene: 52785552

Following gene: 52785554

Centisome position: 41.51

GC content: 52.37

Gene sequence:

>951_bases
ATGACAAGGATCGTTTTTATGGGAACGCCGGATTTTTCCGTCCCGGTGCTCGGCACATTGATTGATGACGGCTATGAGGT
AGTGGGTGTCGTCACCCAGCCTGACCGCCCGAAAGGCAGAAAAAAGGTGATGACTCCGCCGCCTGTCAAGGAGGAAGCGC
TGCGCCGCGGCATTCCCGTGCTCCAGCCTGAGAAAGTGAGGGAAGAAGCGGAAACGGACAAGATTTTGGCGCTTGAACCC
GATTTAATCGTAACGGCGGCATTCGGACAGATCCTGCCGAAAAAGCTCCTCGATTATCCGAAATACGGCTGTATCAATGT
CCATGCCTCTCTTCTGCCGGAGCTGCGCGGAGGAGCCCCGATCCATTACGCCATTCTGGAAGGCAAAGAGAAAACAGGCG
TGACGATCATGTACATGGTCGAAAAATTGGATGCAGGCGATATGCTCGCCAAGGTTGAAGTTGACATCGAAGAAACAGAT
AATGTCGGCACGCTCCACGATAAGCTGAGCAAGGCCGGAGCTGCGCTTCTTTCCGAAACGGTTCCGAGAATCATTGACGG
TTCGGTAACCCCGGAAAAACAGGATGAACAGAAAGCGACATACGCGCCGAACATTAAACGCGAGCAGGAACTGATCGACT
GGTCTAAGCCCGGCGAAGTCCTGTACAACCAAGTCAGAGGCTTGAATCCTTGGCCTGTCGCATACACGGTCTTAAACGGC
CAGACGCTGAAAGTATGGGCCGCGAAAAAATGCCAAGCCTTAAAACAGGCAGAGCCGGGGGAGATCGTCACCGTTGAAAA
AGACGGCATTGTCGTCGCAACCGGAAATGACACCGCGTTAAAATTAACGGAAGTGCAGCCTGCCGGCAAAAAAAGAATGA
AGGCTGAAGATTTTGTCAGGGGAGCGGGTCTTCAAGCCGGAATGAAATTGGGTCATGACGATGAAAAATAA

Upstream 100 bases:

>100_bases
CTGCTGCACGAAATCGACCATTTGGACGGTATTTTATTCACATCAAAAGTAACGCGCTATTATGATGCGGAAGAACTTGA
GGAAATGGAAGGATGATTGG

Downstream 100 bases:

>100_bases
TGTGAGAGAAGTCGCGCTTGATGCACTGATTAAGCTTGACCAGAATCAGGCATACAGCAATCTTTTGCTTCAGTCTGCCA
TGAAAGCGAACGATTTAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTRIVFMGTPDFSVPVLGTLIDDGYEVVGVVTQPDRPKGRKKVMTPPPVKEEALRRGIPVLQPEKVREEAETDKILALEP
DLIVTAAFGQILPKKLLDYPKYGCINVHASLLPELRGGAPIHYAILEGKEKTGVTIMYMVEKLDAGDMLAKVEVDIEETD
NVGTLHDKLSKAGAALLSETVPRIIDGSVTPEKQDEQKATYAPNIKREQELIDWSKPGEVLYNQVRGLNPWPVAYTVLNG
QTLKVWAAKKCQALKQAEPGEIVTVEKDGIVVATGNDTALKLTEVQPAGKKRMKAEDFVRGAGLQAGMKLGHDDEK

Sequences:

>Translated_316_residues
MTRIVFMGTPDFSVPVLGTLIDDGYEVVGVVTQPDRPKGRKKVMTPPPVKEEALRRGIPVLQPEKVREEAETDKILALEP
DLIVTAAFGQILPKKLLDYPKYGCINVHASLLPELRGGAPIHYAILEGKEKTGVTIMYMVEKLDAGDMLAKVEVDIEETD
NVGTLHDKLSKAGAALLSETVPRIIDGSVTPEKQDEQKATYAPNIKREQELIDWSKPGEVLYNQVRGLNPWPVAYTVLNG
QTLKVWAAKKCQALKQAEPGEIVTVEKDGIVVATGNDTALKLTEVQPAGKKRMKAEDFVRGAGLQAGMKLGHDDEK
>Mature_315_residues
TRIVFMGTPDFSVPVLGTLIDDGYEVVGVVTQPDRPKGRKKVMTPPPVKEEALRRGIPVLQPEKVREEAETDKILALEPD
LIVTAAFGQILPKKLLDYPKYGCINVHASLLPELRGGAPIHYAILEGKEKTGVTIMYMVEKLDAGDMLAKVEVDIEETDN
VGTLHDKLSKAGAALLSETVPRIIDGSVTPEKQDEQKATYAPNIKREQELIDWSKPGEVLYNQVRGLNPWPVAYTVLNGQ
TLKVWAAKKCQALKQAEPGEIVTVEKDGIVVATGNDTALKLTEVQPAGKKRMKAEDFVRGAGLQAGMKLGHDDEK

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI238814322, Length=310, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI21614513, Length=317, Percent_Identity=29.3375394321767, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI164663775, Length=326, Percent_Identity=26.9938650306748, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1789683, Length=297, Percent_Identity=46.1279461279461, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI1788589, Length=312, Percent_Identity=31.4102564102564, Blast_Score=165, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI133930964, Length=324, Percent_Identity=31.4814814814815, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6319458, Length=364, Percent_Identity=24.7252747252747, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550868, Length=308, Percent_Identity=30.5194805194805, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571984, Length=230, Percent_Identity=33.0434782608696, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24585660, Length=248, Percent_Identity=29.4354838709677, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_BACLD (Q65JS5)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078967.1
- RefSeq:   YP_091382.1
- ProteinModelPortal:   Q65JS5
- SMR:   Q65JS5
- STRING:   Q65JS5
- EnsemblBacteria:   EBBACT00000056644
- EnsemblBacteria:   EBBACT00000059747
- GeneID:   3030953
- GeneID:   3099767
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01794
- KEGG:   bli:BL02298
- NMPDR:   fig|279010.5.peg.1863
- eggNOG:   COG0223
- GeneTree:   EBGT00050000001190
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- ProtClustDB:   CLSK887288
- BioCyc:   BLIC279010-1:BLI01794-MONOMER
- BioCyc:   BLIC279010:BL02298-MONOMER
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 34580; Mature: 34449

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIVFMGTPDFSVPVLGTLIDDGYEVVGVVTQPDRPKGRKKVMTPPPVKEEALRRGIPV
CCEEEEEECCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCC
LQPEKVREEAETDKILALEPDLIVTAAFGQILPKKLLDYPKYGCINVHASLLPELRGGAP
CCHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAILEGKEKTGVTIMYMVEKLDAGDMLAKVEVDIEETDNVGTLHDKLSKAGAALLSET
EEEEEEECCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
VPRIIDGSVTPEKQDEQKATYAPNIKREQELIDWSKPGEVLYNQVRGLNPWPVAYTVLNG
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECC
QTLKVWAAKKCQALKQAEPGEIVTVEKDGIVVATGNDTALKLTEVQPAGKKRMKAEDFVR
CEEEEEHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEEECCCCCHHHCCHHHHHH
GAGLQAGMKLGHDDEK
CCCCHHCCCCCCCCCC
>Mature Secondary Structure 
TRIVFMGTPDFSVPVLGTLIDDGYEVVGVVTQPDRPKGRKKVMTPPPVKEEALRRGIPV
CEEEEEECCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCC
LQPEKVREEAETDKILALEPDLIVTAAFGQILPKKLLDYPKYGCINVHASLLPELRGGAP
CCHHHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCC
IHYAILEGKEKTGVTIMYMVEKLDAGDMLAKVEVDIEETDNVGTLHDKLSKAGAALLSET
EEEEEEECCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
VPRIIDGSVTPEKQDEQKATYAPNIKREQELIDWSKPGEVLYNQVRGLNPWPVAYTVLNG
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECC
QTLKVWAAKKCQALKQAEPGEIVTVEKDGIVVATGNDTALKLTEVQPAGKKRMKAEDFVR
CEEEEEHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEEECCCCCHHHCCHHHHHH
GAGLQAGMKLGHDDEK
CCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA