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The map label for this gene is yloM [H]

Identifier: 52785554

GI number: 52785554

Start: 1753599

End: 1754945

Strand: Direct

Name: yloM [H]

Synonym: BLi01795

Alternate gene names: 52785554

Gene position: 1753599-1754945 (Clockwise)

Preceding gene: 52785553

Following gene: 52785555

Centisome position: 41.53

GC content: 50.19

Gene sequence:

>1347_bases
ATGAAAAATAATGTGAGAGAAGTCGCGCTTGATGCACTGATTAAGCTTGACCAGAATCAGGCATACAGCAATCTTTTGCT
TCAGTCTGCCATGAAAGCGAACGATTTAAGCGACAAAGACAGAGGCCTTTTGACAGAACTCGTTTACGGCACCCTTCAGA
ATAAGCTGGCGCTTGATTATATGCTGAAGCCGTTTATTAAAAAGCCGGAAAAGGTGAAAGACTGGGTCATCCATCTGTTG
AGAATGTCGCTGTATCAGATGGAATACCTGGAGAAAATCCCTGACCGGGCCGCTCTTTTTGAAGCCGTTGAAATCGCTAA
AAGACGCGGGCATAAAGGAATATCTTCATTTGTTAACGGTGTTCTGCGCTCCGTTCAGAGGGAAGGAGTGCCTTCCTTTG
CGGATATTGCCGATCCGATTGAACGCCTTGCGGTTGAGACAAGCCATCCGGAGTGGCTTGTCAGAGAATGGACGGATGCC
TACGGGTTCGAAGCGGCAGAACAAATCTGCCGGATTCATATGATCCCGCCGAAGCAGACGATCCGCGTCAACAGGCTGAA
AAACGACCGGGATACGCTTCTTTCCCGTCTGAATGAAGCGGGGATTGAGGCGGAAGAAGGCGACTTGTCCAAAGACGCTG
TCAAACTGCTGAAAGGAACGATTGCGTCCACTCCTTTTTTCAAAGAAGGCGAAGTCACCATACAAGATGAAAGCTCAATG
CTAGTAGCGAGAGCCCTTGGACCTGAGCGGGGAGAAACAGTGCTGGATGCATGCGCAGCTCCGGGAGGAAAATCCACTCA
TATCGGCGAACTGCTCGAAGATACGGGAAAGGTCGTCTCCCTGGACCTTCATCAGCATAAAGTAAAGCTGATCAAAGAAG
CGGCAGGCCGGATTGGACTTTCCAACATTGAAGCAAGAGCGCTGGATGCCAGAAAAGCCGGAGAAGTCTTCGAACCGGAA
CAGTTCGACCGGATCCTCGTCGATGCCCCGTGTTCGGGATTCGGCGTCATCCGCAGAAAACCGGATCTCAAATACAGCAA
AACGCCCGAAGACAGCGCGCGTCTCGCCGGGATTCAGCTTGCGATTTTAAACGAAATCGCACCTTTATTGAAAACAGGCG
GGACATTGGTTTACAGCACATGCACAATGGACCCGACCGAAAATGAACAAGTCATGCATGCTTTTTTGGAAGAACACGAC
GAATTTGAAGCGGACCCCACCCTCGCCGAGCGGCTGCCCGAAAAAGCGGCGCCGTATGTCAAGGATGGAAGCATTCAAAT
CCTTCCCCACTACTTTGGAACGGACGGCTTCTTTATTTGCAGCATGAGAAAGAAGGGATCACAATAA

Upstream 100 bases:

>100_bases
AAATTAACGGAAGTGCAGCCTGCCGGCAAAAAAAGAATGAAGGCTGAAGATTTTGTCAGGGGAGCGGGTCTTCAAGCCGG
AATGAAATTGGGTCATGACG

Downstream 100 bases:

>100_bases
TGGAATCGAAACAAAAAGTAAGAAAAGAATTGCGGACAGAAAGACCGTCCATCTATTCTTTTGAAATAGAAGAACTGAAA
AGCTGGCTATCGGAAAACGG

Product: YloM

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKNNVREVALDALIKLDQNQAYSNLLLQSAMKANDLSDKDRGLLTELVYGTLQNKLALDYMLKPFIKKPEKVKDWVIHLL
RMSLYQMEYLEKIPDRAALFEAVEIAKRRGHKGISSFVNGVLRSVQREGVPSFADIADPIERLAVETSHPEWLVREWTDA
YGFEAAEQICRIHMIPPKQTIRVNRLKNDRDTLLSRLNEAGIEAEEGDLSKDAVKLLKGTIASTPFFKEGEVTIQDESSM
LVARALGPERGETVLDACAAPGGKSTHIGELLEDTGKVVSLDLHQHKVKLIKEAAGRIGLSNIEARALDARKAGEVFEPE
QFDRILVDAPCSGFGVIRRKPDLKYSKTPEDSARLAGIQLAILNEIAPLLKTGGTLVYSTCTMDPTENEQVMHAFLEEHD
EFEADPTLAERLPEKAAPYVKDGSIQILPHYFGTDGFFICSMRKKGSQ

Sequences:

>Translated_448_residues
MKNNVREVALDALIKLDQNQAYSNLLLQSAMKANDLSDKDRGLLTELVYGTLQNKLALDYMLKPFIKKPEKVKDWVIHLL
RMSLYQMEYLEKIPDRAALFEAVEIAKRRGHKGISSFVNGVLRSVQREGVPSFADIADPIERLAVETSHPEWLVREWTDA
YGFEAAEQICRIHMIPPKQTIRVNRLKNDRDTLLSRLNEAGIEAEEGDLSKDAVKLLKGTIASTPFFKEGEVTIQDESSM
LVARALGPERGETVLDACAAPGGKSTHIGELLEDTGKVVSLDLHQHKVKLIKEAAGRIGLSNIEARALDARKAGEVFEPE
QFDRILVDAPCSGFGVIRRKPDLKYSKTPEDSARLAGIQLAILNEIAPLLKTGGTLVYSTCTMDPTENEQVMHAFLEEHD
EFEADPTLAERLPEKAAPYVKDGSIQILPHYFGTDGFFICSMRKKGSQ
>Mature_448_residues
MKNNVREVALDALIKLDQNQAYSNLLLQSAMKANDLSDKDRGLLTELVYGTLQNKLALDYMLKPFIKKPEKVKDWVIHLL
RMSLYQMEYLEKIPDRAALFEAVEIAKRRGHKGISSFVNGVLRSVQREGVPSFADIADPIERLAVETSHPEWLVREWTDA
YGFEAAEQICRIHMIPPKQTIRVNRLKNDRDTLLSRLNEAGIEAEEGDLSKDAVKLLKGTIASTPFFKEGEVTIQDESSM
LVARALGPERGETVLDACAAPGGKSTHIGELLEDTGKVVSLDLHQHKVKLIKEAAGRIGLSNIEARALDARKAGEVFEPE
QFDRILVDAPCSGFGVIRRKPDLKYSKTPEDSARLAGIQLAILNEIAPLLKTGGTLVYSTCTMDPTENEQVMHAFLEEHD
EFEADPTLAERLPEKAAPYVKDGSIQILPHYFGTDGFFICSMRKKGSQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=357, Percent_Identity=30.812324929972, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI76150623, Length=357, Percent_Identity=30.812324929972, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI32698918, Length=168, Percent_Identity=41.6666666666667, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI39995082, Length=280, Percent_Identity=27.1428571428571, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI301336155, Length=280, Percent_Identity=27.1428571428571, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI8922322, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI270288818, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI23199998, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI270288816, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI2367212, Length=447, Percent_Identity=36.0178970917226, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87081985, Length=285, Percent_Identity=33.6842105263158, Blast_Score=138, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17536757, Length=286, Percent_Identity=33.2167832167832, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI25143471, Length=179, Percent_Identity=33.5195530726257, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534021, Length=169, Percent_Identity=32.5443786982249, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=171, Percent_Identity=32.1637426900585, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17509941, Length=160, Percent_Identity=31.875, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=282, Percent_Identity=32.9787234042553, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319447, Length=177, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324306, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI22024126, Length=279, Percent_Identity=30.4659498207885, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24668781, Length=235, Percent_Identity=34.0425531914894, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356513, Length=235, Percent_Identity=34.0425531914894, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355201, Length=192, Percent_Identity=30.7291666666667, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356579, Length=230, Percent_Identity=26.9565217391304, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19920494, Length=180, Percent_Identity=33.8888888888889, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49938; Mature: 49938

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNVREVALDALIKLDQNQAYSNLLLQSAMKANDLSDKDRGLLTELVYGTLQNKLALDY
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MLKPFIKKPEKVKDWVIHLLRMSLYQMEYLEKIPDRAALFEAVEIAKRRGHKGISSFVNG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VLRSVQREGVPSFADIADPIERLAVETSHPEWLVREWTDAYGFEAAEQICRIHMIPPKQT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHEECCCCCHH
IRVNRLKNDRDTLLSRLNEAGIEAEEGDLSKDAVKLLKGTIASTPFFKEGEVTIQDESSM
EEHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
LVARALGPERGETVLDACAAPGGKSTHIGELLEDTGKVVSLDLHQHKVKLIKEAAGRIGL
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
SNIEARALDARKAGEVFEPEQFDRILVDAPCSGFGVIRRKPDLKYSKTPEDSARLAGIQL
CCCHHHHHHHHHCCCCCCCHHHCEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHHHHHH
AILNEIAPLLKTGGTLVYSTCTMDPTENEQVMHAFLEEHDEFEADPTLAERLPEKAAPYV
HHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCHHHCCCCE
KDGSIQILPHYFGTDGFFICSMRKKGSQ
ECCCEEEEEHEECCCCEEEEECCCCCCC
>Mature Secondary Structure
MKNNVREVALDALIKLDQNQAYSNLLLQSAMKANDLSDKDRGLLTELVYGTLQNKLALDY
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
MLKPFIKKPEKVKDWVIHLLRMSLYQMEYLEKIPDRAALFEAVEIAKRRGHKGISSFVNG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
VLRSVQREGVPSFADIADPIERLAVETSHPEWLVREWTDAYGFEAAEQICRIHMIPPKQT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHEECCCCCHH
IRVNRLKNDRDTLLSRLNEAGIEAEEGDLSKDAVKLLKGTIASTPFFKEGEVTIQDESSM
EEHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
LVARALGPERGETVLDACAAPGGKSTHIGELLEDTGKVVSLDLHQHKVKLIKEAAGRIGL
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
SNIEARALDARKAGEVFEPEQFDRILVDAPCSGFGVIRRKPDLKYSKTPEDSARLAGIQL
CCCHHHHHHHHHCCCCCCCHHHCEEEEECCCCCCCCEECCCCCCCCCCCCCHHHHHHHHH
AILNEIAPLLKTGGTLVYSTCTMDPTENEQVMHAFLEEHDEFEADPTLAERLPEKAAPYV
HHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCHHHCCCCE
KDGSIQILPHYFGTDGFFICSMRKKGSQ
ECCCEEEEEHEECCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]