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The map label for this gene is spoVD [H]

Identifier: 52785493

GI number: 52785493

Start: 1687968

End: 1689902

Strand: Direct

Name: spoVD [H]

Synonym: BLi01734

Alternate gene names: 52785493

Gene position: 1687968-1689902 (Clockwise)

Preceding gene: 52785492

Following gene: 52785494

Centisome position: 39.97

GC content: 50.08

Gene sequence:

>1935_bases
TTGCGCGTTTCCAATGTAACGGTCAGAAAACGTTTAATATTCGTTCTGCTTTTTGGTGTGATCATCTTTTTGATTATTGA
TACAAGGCTCGGATACGTTCAGTTCGTTCTCGGGGATAAACTGACGACTTTAGCAAAAGATTCTTGGAGCCGGAACCTTC
CTTTTGAGCCGGAAAGGGGCGAAATATTGGACAGGAACGGCGTCAAGCTGGCAACAAACCAAAGCGCGCCATCGGTTTTG
GTTGTTCCGAAGCAAGTTGAAAATCCGATCAAAACGAGCAGACTGCTGGCCAGCGTTTTGAATATGTCGGAAGAAAAAGC
GTATAAACATGTCACGAAAAAAACGTCGATTGAAAGGATCAATCCCGAGGGCCGGAAGATTTCCCACGAGAAAGCAAAAG
AAGTCAGAGATCTCAATTTGAAAGGCGTATACATCGCAGAAGACTCGATCCGCCATTATCCGTTCGGCAGCTATCTGTCC
CATGTGCTCGGATTTGCGGGCATTGACAACCAGGGTCTGCTCGGCCTTGAAGCCTTTTATGACAAAGAGCTGAAGGGCGA
AAAGGGCTATGTGAAATTTTATTCCGATGCAAAAGGCAAGAGAATGCCTGGGGAGGCGGATGACTATACCCCGCCGAAAG
ACGGGCTTGATATGAAGCTGACGATCGATTCAAAGGTGCAGACGATCATGGAGCGGGAATTTGATATCGCAGAAGCGAAG
TATAATCCGGACGGTATGGTCGGTGTTGCGATGAATCCGAAAAACGGGGAGATATTGGCGATGGTCAGCCGGCCGGACTT
TGATCCCGCAAACTACCAATCAATCGATCCCAAAGTCTATAACCGGAACCTGCCTGTATGGAGCACATATGAGCCGGGTT
CTACTTTTAAAATCATCACGCTTGCCGCAGCTTTGGAGGAAAACAAAGTCAACCTCCAAAAAGATCAATTCTATGATAAA
GGTTCCGTTGAAGTGGACGGCGCGAGGCTGAAGTGCTGGAAGCGCGGCGGACACGGCGCACAATCGTTTCTTGAAGTCGT
CCAAAATTCGTGCAACCCGGGATTTGTTGAGCTTGGTCAGCGGCTCGGCAAAGAAAAACTGTTCACCTACATTAAAAGTT
TCGGCTTCGGACAAAAAACCGGGATCGATCTGCAAGGCGAAGGAACAGGCATCCTATTCCCTCTTGACCGCGTCGGCCCC
GTAGAGCAGGCGACAACAGCTTTCGGGCAGGGGGTATCGGTGACGCCGATCCAGCAGGTCACGGCCGTTTCTGCGGCTGT
TAACGGCGGAACGCTGTATACGCCGTATATTGCCAAAGAGTGGATTGATCCCGTGACAAAACAAACAGTGAAAAAACAGA
CGCCGATCGCCAAAAGAAAAGTGATTTCTGAAGAGACATCCAAACAGATCCGCTACGCGCTGGAGAGCGTTGTCGCCCAG
GGGACGGGGCGGAACGCTTTTGTCGACGGCTACCGGGTCGGCGGCAAAACCGGTACGGCGCAAAAAGTAAAAGACGGGAA
ATATTTGAAAAACAACCACATCGTCTCATTTATCGGAACGGCTCCTTCAGATGATCCGAGCATTGTCGTCTACGTCGCCG
TCGACAACCCGAAAGGAACGATTCAATTCGGGGGTACGGTTGCAGCGCCGATCGTCGGAAACATCATGAGAGACAGTCTT
CCGCAGCTCGGCGTTAAGAAGCGGAAAGATCAGATCGAACGCGAATATCAATGGCTGGACAAAAAGCTGATCGAGGTCCC
GAACCTTATAGGGCTTTCCGTGACAGAGCTTGAACCATTGCTGATCAACCTCAGGCTGAAGGCTTCCGGAGAAGGCGATG
TCGTCGTTCAGCAGTCCCCTAAGCCGGGCGAAAAAGTAAAAGAAGGATCGACGATTCGCATTTATCTTGACAGCGATGAC
GGAGCCTCTGATTAA

Upstream 100 bases:

>100_bases
TTGGACGCGGCCGCCTTGAATAGATGAAAAATCGGGCCGTTCTATCAAAACGCTCCGAGGCATAAAATGAAACAAGCCTA
AATAAGGAGTGAACGGTCTC

Downstream 100 bases:

>100_bases
TTCGTTTCAATATAGGAGCGGCTGCCTGCTGATGTCCGGGGCCGTTCCTCCTAAAAAATATATCGATTTTAAAGGATTAG
CTGGATGTATCCTCTTTTTT

Product: SpoVD

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MRVSNVTVRKRLIFVLLFGVIIFLIIDTRLGYVQFVLGDKLTTLAKDSWSRNLPFEPERGEILDRNGVKLATNQSAPSVL
VVPKQVENPIKTSRLLASVLNMSEEKAYKHVTKKTSIERINPEGRKISHEKAKEVRDLNLKGVYIAEDSIRHYPFGSYLS
HVLGFAGIDNQGLLGLEAFYDKELKGEKGYVKFYSDAKGKRMPGEADDYTPPKDGLDMKLTIDSKVQTIMEREFDIAEAK
YNPDGMVGVAMNPKNGEILAMVSRPDFDPANYQSIDPKVYNRNLPVWSTYEPGSTFKIITLAAALEENKVNLQKDQFYDK
GSVEVDGARLKCWKRGGHGAQSFLEVVQNSCNPGFVELGQRLGKEKLFTYIKSFGFGQKTGIDLQGEGTGILFPLDRVGP
VEQATTAFGQGVSVTPIQQVTAVSAAVNGGTLYTPYIAKEWIDPVTKQTVKKQTPIAKRKVISEETSKQIRYALESVVAQ
GTGRNAFVDGYRVGGKTGTAQKVKDGKYLKNNHIVSFIGTAPSDDPSIVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PQLGVKKRKDQIEREYQWLDKKLIEVPNLIGLSVTELEPLLINLRLKASGEGDVVVQQSPKPGEKVKEGSTIRIYLDSDD
GASD

Sequences:

>Translated_644_residues
MRVSNVTVRKRLIFVLLFGVIIFLIIDTRLGYVQFVLGDKLTTLAKDSWSRNLPFEPERGEILDRNGVKLATNQSAPSVL
VVPKQVENPIKTSRLLASVLNMSEEKAYKHVTKKTSIERINPEGRKISHEKAKEVRDLNLKGVYIAEDSIRHYPFGSYLS
HVLGFAGIDNQGLLGLEAFYDKELKGEKGYVKFYSDAKGKRMPGEADDYTPPKDGLDMKLTIDSKVQTIMEREFDIAEAK
YNPDGMVGVAMNPKNGEILAMVSRPDFDPANYQSIDPKVYNRNLPVWSTYEPGSTFKIITLAAALEENKVNLQKDQFYDK
GSVEVDGARLKCWKRGGHGAQSFLEVVQNSCNPGFVELGQRLGKEKLFTYIKSFGFGQKTGIDLQGEGTGILFPLDRVGP
VEQATTAFGQGVSVTPIQQVTAVSAAVNGGTLYTPYIAKEWIDPVTKQTVKKQTPIAKRKVISEETSKQIRYALESVVAQ
GTGRNAFVDGYRVGGKTGTAQKVKDGKYLKNNHIVSFIGTAPSDDPSIVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PQLGVKKRKDQIEREYQWLDKKLIEVPNLIGLSVTELEPLLINLRLKASGEGDVVVQQSPKPGEKVKEGSTIRIYLDSDD
GASD
>Mature_644_residues
MRVSNVTVRKRLIFVLLFGVIIFLIIDTRLGYVQFVLGDKLTTLAKDSWSRNLPFEPERGEILDRNGVKLATNQSAPSVL
VVPKQVENPIKTSRLLASVLNMSEEKAYKHVTKKTSIERINPEGRKISHEKAKEVRDLNLKGVYIAEDSIRHYPFGSYLS
HVLGFAGIDNQGLLGLEAFYDKELKGEKGYVKFYSDAKGKRMPGEADDYTPPKDGLDMKLTIDSKVQTIMEREFDIAEAK
YNPDGMVGVAMNPKNGEILAMVSRPDFDPANYQSIDPKVYNRNLPVWSTYEPGSTFKIITLAAALEENKVNLQKDQFYDK
GSVEVDGARLKCWKRGGHGAQSFLEVVQNSCNPGFVELGQRLGKEKLFTYIKSFGFGQKTGIDLQGEGTGILFPLDRVGP
VEQATTAFGQGVSVTPIQQVTAVSAAVNGGTLYTPYIAKEWIDPVTKQTVKKQTPIAKRKVISEETSKQIRYALESVVAQ
GTGRNAFVDGYRVGGKTGTAQKVKDGKYLKNNHIVSFIGTAPSDDPSIVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PQLGVKKRKDQIEREYQWLDKKLIEVPNLIGLSVTELEPLLINLRLKASGEGDVVVQQSPKPGEKVKEGSTIRIYLDSDD
GASD

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=568, Percent_Identity=28.5211267605634, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI1786854, Length=632, Percent_Identity=25, Blast_Score=158, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71073; Mature: 71073

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSNVTVRKRLIFVLLFGVIIFLIIDTRLGYVQFVLGDKLTTLAKDSWSRNLPFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCC
EILDRNGVKLATNQSAPSVLVVPKQVENPIKTSRLLASVLNMSEEKAYKHVTKKTSIERI
CEECCCCEEEEECCCCCEEEEECHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHC
NPEGRKISHEKAKEVRDLNLKGVYIAEDSIRHYPFGSYLSHVLGFAGIDNQGLLGLEAFY
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEHHHHH
DKELKGEKGYVKFYSDAKGKRMPGEADDYTPPKDGLDMKLTIDSKVQTIMEREFDIAEAK
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHCC
YNPDGMVGVAMNPKNGEILAMVSRPDFDPANYQSIDPKVYNRNLPVWSTYEPGSTFKIIT
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCEEECCCCCCCEEEEE
LAAALEENKVNLQKDQFYDKGSVEVDGARLKCWKRGGHGAQSFLEVVQNSCNPGFVELGQ
EEEHHHCCCCCCCHHHCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHH
RLGKEKLFTYIKSFGFGQKTGIDLQGEGTGILFPLDRVGPVEQATTAFGQGVSVTPIQQV
HHCHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEHHCCCCHHHHHHHHCCCCCCCHHHHH
TAVSAAVNGGTLYTPYIAKEWIDPVTKQTVKKQTPIAKRKVISEETSKQIRYALESVVAQ
HHHHHEECCCEEECCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTGRNAFVDGYRVGGKTGTAQKVKDGKYLKNNHIVSFIGTAPSDDPSIVVYVAVDNPKGT
CCCCCEEECCEEECCCCCCCHHCCCCCEECCCCEEEEEECCCCCCCCEEEEEEECCCCCE
IQFGGTVAAPIVGNIMRDSLPQLGVKKRKDQIEREYQWLDKKLIEVPNLIGLSVTELEPL
EEECCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEE
LINLRLKASGEGDVVVQQSPKPGEKVKEGSTIRIYLDSDDGASD
EEEEEEEECCCCCEEEECCCCCCHHHCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MRVSNVTVRKRLIFVLLFGVIIFLIIDTRLGYVQFVLGDKLTTLAKDSWSRNLPFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCC
EILDRNGVKLATNQSAPSVLVVPKQVENPIKTSRLLASVLNMSEEKAYKHVTKKTSIERI
CEECCCCEEEEECCCCCEEEEECHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHC
NPEGRKISHEKAKEVRDLNLKGVYIAEDSIRHYPFGSYLSHVLGFAGIDNQGLLGLEAFY
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEHHHHH
DKELKGEKGYVKFYSDAKGKRMPGEADDYTPPKDGLDMKLTIDSKVQTIMEREFDIAEAK
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCHHHCC
YNPDGMVGVAMNPKNGEILAMVSRPDFDPANYQSIDPKVYNRNLPVWSTYEPGSTFKIIT
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCEEECCCCCCCEEEEE
LAAALEENKVNLQKDQFYDKGSVEVDGARLKCWKRGGHGAQSFLEVVQNSCNPGFVELGQ
EEEHHHCCCCCCCHHHCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHH
RLGKEKLFTYIKSFGFGQKTGIDLQGEGTGILFPLDRVGPVEQATTAFGQGVSVTPIQQV
HHCHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEHHCCCCHHHHHHHHCCCCCCCHHHHH
TAVSAAVNGGTLYTPYIAKEWIDPVTKQTVKKQTPIAKRKVISEETSKQIRYALESVVAQ
HHHHHEECCCEEECCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTGRNAFVDGYRVGGKTGTAQKVKDGKYLKNNHIVSFIGTAPSDDPSIVVYVAVDNPKGT
CCCCCEEECCEEECCCCCCCHHCCCCCEECCCCEEEEEECCCCCCCCEEEEEEECCCCCE
IQFGGTVAAPIVGNIMRDSLPQLGVKKRKDQIEREYQWLDKKLIEVPNLIGLSVTELEPL
EEECCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEE
LINLRLKASGEGDVVVQQSPKPGEKVKEGSTIRIYLDSDDGASD
EEEEEEEECCCCCEEEECCCCCCHHHCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]