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The map label for this gene is yjmD [H]

Identifier: 52785123

GI number: 52785123

Start: 1346064

End: 1347080

Strand: Direct

Name: yjmD [H]

Synonym: BLi01355

Alternate gene names: 52785123

Gene position: 1346064-1347080 (Clockwise)

Preceding gene: 52785122

Following gene: 52785124

Centisome position: 31.88

GC content: 51.03

Gene sequence:

>1017_bases
GTGAAAGCTGCGGTGATGACGAAGCCTTATTCGATTGAATTTCACGACATACCGCGTCCCGAACCGGCCAGCGGTGAAGT
CCTTGTCAAGATAAAGGCTGCCGGGATTTGCGGAAGTGATGTGCATTTTTACGACGGCTCAAATCCATATGCACAGTACC
CTCAGATCTTTGGACATGAGCTTGCAGGCATCATTGAAAAAACGGGGGCCGGCGTGAGGGGGCGATCCGCAGGCGAACGG
GTCGTAATTGAACCGGCGATCCCGTGCGGAGGCTGCTACCCTTGTCGGAAAGGGAGGACAAACGCCTGTATGAACATCGA
TATGATCGGGTCGGTTCGCAGAGGAGGGTTCGCTGATTTTATCATTGTTCCAGAAACGCATGTCCATCCGATTCCTGAGC
AAATGGATTTTGCAACCGCTGCTTTGTGCGAGCCGTTTTCAATCGGAGCGCAGGCGGTTCGGCGGGCAGATATTCAAACA
GGCGAAACGATTGTCATATTGGGAATGGGTCCGATCGGGTTAACGATTTTGGCGCAGGTAAAAAAGCGCTTCGACGTTCG
TGTGATCGCTGTCGATCCTGTAAGGGAAAGGCTTGAGCTTGCCGAGGCATTCGGGGCGGATGCCGTTATTCAGCCTGGTG
AAGAGGATGCAGAGCAAATGATTCTGAAGCTGACAGGCGGAGAAGGAGCGGGGATTGTGTTCGAAGCGGCCGGGATTCCC
GCGACGATTGAGCAATCCGTTCGTTTGGCGGCCGCCGCCGGGCGCATTGTCATTGTCGGCTTAACGGGGAGGAATGTGAC
GATTCCGGGTCTTCTTCTCACAAAGAAAGATATTGAAATTTATGGAACAAAACACAGCGTCAATCAATTTCCCGGCGTCA
TTCAATTTTTGAATGAAAACCCTGAAATAGCCCGGGCTTTTGTCACTGAGATCATGCCTTTTATGGAAATAGAAGAGGCG
TTGAAAAAAGCGAAAAACTGTCCCCATCAGGTCACAAAGATCATTTTATCTTATTGA

Upstream 100 bases:

>100_bases
GCCGAAGAGCATTTGCAGCTGGTCATCGTCGATAAACAGATGCTCATTGATGAGTTTCCCGGTTATTTCAAAAAGTAAGC
GCTTTAAAAGGAGTGGTGAT

Downstream 100 bases:

>100_bases
ATCGGTGAGGAGGAAGTGTGATGAAAATGGTTTTCAGATGGTATGGAGAAGGAAACGACTCCGTCACCCTTGAGCAGATC
AGGCAGATTCCCGGTGTGGA

Product: YjmD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKAAVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNPYAQYPQIFGHELAGIIEKTGAGVRGRSAGER
VVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVRRGGFADFIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQT
GETIVILGMGPIGLTILAQVKKRFDVRVIAVDPVRERLELAEAFGADAVIQPGEEDAEQMILKLTGGEGAGIVFEAAGIP
ATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVIQFLNENPEIARAFVTEIMPFMEIEEA
LKKAKNCPHQVTKIILSY

Sequences:

>Translated_338_residues
MKAAVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNPYAQYPQIFGHELAGIIEKTGAGVRGRSAGER
VVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVRRGGFADFIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQT
GETIVILGMGPIGLTILAQVKKRFDVRVIAVDPVRERLELAEAFGADAVIQPGEEDAEQMILKLTGGEGAGIVFEAAGIP
ATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVIQFLNENPEIARAFVTEIMPFMEIEEA
LKKAKNCPHQVTKIILSY
>Mature_338_residues
MKAAVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNPYAQYPQIFGHELAGIIEKTGAGVRGRSAGER
VVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVRRGGFADFIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQT
GETIVILGMGPIGLTILAQVKKRFDVRVIAVDPVRERLELAEAFGADAVIQPGEEDAEQMILKLTGGEGAGIVFEAAGIP
ATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVIQFLNENPEIARAFVTEIMPFMEIEEA
LKKAKNCPHQVTKIILSY

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=327, Percent_Identity=29.9694189602446, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4501933, Length=354, Percent_Identity=30.7909604519774, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI34577061, Length=354, Percent_Identity=30.225988700565, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4501929, Length=355, Percent_Identity=30.7042253521127, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI262073058, Length=358, Percent_Identity=27.3743016759777, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI71743840, Length=358, Percent_Identity=27.3743016759777, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI71565154, Length=356, Percent_Identity=26.123595505618, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI156523966, Length=363, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4501939, Length=363, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI194239674, Length=254, Percent_Identity=24.0157480314961, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI13236495, Length=254, Percent_Identity=24.0157480314961, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787863, Length=339, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1788073, Length=342, Percent_Identity=32.4561403508772, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI226510992, Length=330, Percent_Identity=31.8181818181818, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1788407, Length=291, Percent_Identity=31.6151202749141, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1790045, Length=338, Percent_Identity=29.8816568047337, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1790718, Length=321, Percent_Identity=28.0373831775701, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082125, Length=276, Percent_Identity=29.3478260869565, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788075, Length=261, Percent_Identity=28.3524904214559, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786825, Length=355, Percent_Identity=26.7605633802817, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081918, Length=330, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786552, Length=354, Percent_Identity=27.4011299435028, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082401, Length=317, Percent_Identity=24.2902208201893, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=331, Percent_Identity=29.0030211480363, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17562878, Length=331, Percent_Identity=29.607250755287, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17562584, Length=294, Percent_Identity=29.5918367346939, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25146526, Length=359, Percent_Identity=25.9052924791086, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=290, Percent_Identity=28.6206896551724, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71997431, Length=359, Percent_Identity=24.7910863509749, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565904, Length=331, Percent_Identity=23.8670694864048, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544682, Length=319, Percent_Identity=22.5705329153605, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=346, Percent_Identity=28.0346820809249, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319257, Length=356, Percent_Identity=27.5280898876405, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319258, Length=297, Percent_Identity=30.6397306397306, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322619, Length=324, Percent_Identity=27.1604938271605, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319955, Length=324, Percent_Identity=26.8518518518519, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6319621, Length=256, Percent_Identity=30.46875, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=256, Percent_Identity=30.078125, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320033, Length=354, Percent_Identity=24.5762711864407, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=256, Percent_Identity=29.6875, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323729, Length=256, Percent_Identity=27.734375, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319520, Length=318, Percent_Identity=23.2704402515723, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17737897, Length=333, Percent_Identity=28.8288288288288, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17137530, Length=336, Percent_Identity=27.9761904761905, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17737895, Length=356, Percent_Identity=26.4044943820225, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221457811, Length=328, Percent_Identity=24.390243902439, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45550770, Length=328, Percent_Identity=24.390243902439, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45551930, Length=328, Percent_Identity=24.390243902439, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 36359; Mature: 36359

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNPYAQYPQIFGHE
CCCCEECCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCHHCHHHHHHH
LAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVRRGGFADF
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQTGETIVILGMGPIGLTILAQV
EEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHH
KKRFDVRVIAVDPVRERLELAEAFGADAVIQPGEEDAEQMILKLTGGEGAGIVFEAAGIP
HHHCCEEEEEECCHHHHHHHHHHHCCCCEECCCHHHHHEEEEEEECCCCCEEEEEECCCC
ATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVIQFLNEN
HHHHHHHHHEEECCCEEEEEECCCCEECCEEEEEECCEEEEECCCCHHHCCHHHHHHCCC
PEIARAFVTEIMPFMEIEEALKKAKNCPHQVTKIILSY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MKAAVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNPYAQYPQIFGHE
CCCCEECCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCHHCHHHHHHH
LAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVRRGGFADF
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQTGETIVILGMGPIGLTILAQV
EEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHH
KKRFDVRVIAVDPVRERLELAEAFGADAVIQPGEEDAEQMILKLTGGEGAGIVFEAAGIP
HHHCCEEEEEECCHHHHHHHHHHHCCCCEECCCHHHHHEEEEEEECCCCCEEEEEECCCC
ATIEQSVRLAAAAGRIVIVGLTGRNVTIPGLLLTKKDIEIYGTKHSVNQFPGVIQFLNEN
HHHHHHHHHEEECCCEEEEEECCCCEECCEEEEEECCEEEEECCCCHHHCCHHHHHHCCC
PEIARAFVTEIMPFMEIEEALKKAKNCPHQVTKIILSY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]