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The map label for this gene is fdrA [H]

Identifier: 52784903

GI number: 52784903

Start: 1134463

End: 1136220

Strand: Direct

Name: fdrA [H]

Synonym: BLi01131

Alternate gene names: 52784903

Gene position: 1134463-1136220 (Clockwise)

Preceding gene: 52784902

Following gene: 52784904

Centisome position: 26.87

GC content: 38.74

Gene sequence:

>1758_bases
ATGTTATACACAATTATAAAAGAAAACACCTATCAAGATTCTATCGTGTTAATGCTTTTATCAAACAAGTTATCTGCAAT
AGATGGTATAAACAAAGTTTCTATCATGATGGGAACACCAGCTAACAAAGACATTTTTAAATCTTCGGGTTTGGGCACAG
ATGAATTGGAAAAAGCAAACCCAAATGATATCGTCATCGTTATAGATACAAACCAAGAAGAAAAGGTATCGGAAGTGAAA
GAAGAAGTAGAAGCAGCTTTAAAAGGAGACTCTGCTTCACAAGACAGAGCTAAAGACCAAGAAGCACATAACTGGAAGCG
TGCAATGGAGCTTGCGAACAACCCTAATCTGGCATTGATCTCCATTCCTGGTCAGTATGCAGCAATGGAAGCGGAAAATG
CATTGAATGAAGGGTTACATGTATTTCTATTCAGCGACAATGTATCTAAAGAAGATGAGGTTAAGTTGAAACAAAAGGCG
CATGAAAAAGGATTATTAGTCATGGGACCAGACTGCGGTACTGGAATTATTCACGGCGTGCCACTGGCATTTACAAATAT
CGTGAATAAAGGAGATATTGGCGTTGTGGGTGCATCAGGTACAGGGATTCAGGAAGTGACATGCATCATTGACCGTCTTG
GTAAAGGTGTAACAAACGCAATTGGTACAGGTGGTCGGGATTTATCAACAGAGGTTGGTGCTACCATGGTTTTAGATAGT
ATCAAAGCATTAAATCAAGATCCACAAGTAAAAGTGATTACAGTAATTTCTAAACCGCCTGCAAAGGAAGTGCAGCAAAA
AGTATTAAATGTGTTAAGAAATATTGAAAAACCGGTTGTTACGTTATTTTTAGGAGATAAACCAACTTATCAGGAAGAAA
ATATTTATCATGCGTATACACTTGAAGAAGCAGCGGTTGTATCTGTTCAATTATCCAATGGCGACAAACCGAATTTTAAA
CCGACAGTGGCTGAAAATGTAAACGTGTCGTTAAAAGATTCACAAGTTGGTATTAAAGGTTATTACTCGGGCGGCACCTT
GGCATCTGAAGCAGCTGTGTTAGTGAAAGAGGCATTCAAAGAAGAAGTACCTGAAGAGAAGAAAGGTGCCTATATTCTAA
AAACAAAACATCATGAAATTATTGACTTAGGCGATGATATTTATACCCAGGGGAAGCCACACCCGATGATTGATCCTGAA
AAACGCATCGAAATGCTTGAAACATCTGGAAACGATCCTGAAACAGCAGTCATCATGATTGATAACGTCATTGGCTATGG
CAGTCATGATGATATGGCAAATGAATTAGCACCAGCCATTAAACGTATTTTAGCCAATGCACATCAGGATGGCCGTGAAC
TTGCAGTGCTTGTAACAGTTGTAGGTACAGATAAAGATCCTCAAGGTTACGAAAAGCAAATTGAAACCTTAAAAGAAAGT
GGTGCAATGATTTGTGAGACAAACGATCAAATGGTTCGTACAGCGATTAAACTGGCAGGAGGAAAAGTGGAACAGCCAGT
CCTTGACATACAAAAATTTGAATATACCCAAGAAGACTTGACAGTAGACGAAAAAATTATGTCCTTAATCAATACGAAAC
CAAGTGTCATCAATATTGGGCTGAAAAGTTTTACAGCAGCTGTTCAGAAGAGCGGATCAGAGTGTGTTCAATTTAACTGG
CGGCCAATTGCTGGCGGTGATGAAAAGCTAATGAAAGTGCTTCAATATCTAAACTACTATGAAGGAGAGACAATCTAA

Upstream 100 bases:

>100_bases
TTGTAGACGATATTTATAACTACCTCGTTTCAGGCGATGTTCATTACAATCGTTATCATGGAAAGAATAGATTTGCAGAA
TAACAAAATGGAGGATCATT

Downstream 100 bases:

>100_bases
TGGGGTACAAAACAATAAATGAAGCGAACGAAGCTGTTATCCGGAAGATCATAGCAGCTGAACCATTCTTGACCGATGTT
GTACCTGCCAAGTCTGTGAT

Product: membrane protein FdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MLYTIIKENTYQDSIVLMLLSNKLSAIDGINKVSIMMGTPANKDIFKSSGLGTDELEKANPNDIVIVIDTNQEEKVSEVK
EEVEAALKGDSASQDRAKDQEAHNWKRAMELANNPNLALISIPGQYAAMEAENALNEGLHVFLFSDNVSKEDEVKLKQKA
HEKGLLVMGPDCGTGIIHGVPLAFTNIVNKGDIGVVGASGTGIQEVTCIIDRLGKGVTNAIGTGGRDLSTEVGATMVLDS
IKALNQDPQVKVITVISKPPAKEVQQKVLNVLRNIEKPVVTLFLGDKPTYQEENIYHAYTLEEAAVVSVQLSNGDKPNFK
PTVAENVNVSLKDSQVGIKGYYSGGTLASEAAVLVKEAFKEEVPEEKKGAYILKTKHHEIIDLGDDIYTQGKPHPMIDPE
KRIEMLETSGNDPETAVIMIDNVIGYGSHDDMANELAPAIKRILANAHQDGRELAVLVTVVGTDKDPQGYEKQIETLKES
GAMICETNDQMVRTAIKLAGGKVEQPVLDIQKFEYTQEDLTVDEKIMSLINTKPSVINIGLKSFTAAVQKSGSECVQFNW
RPIAGGDEKLMKVLQYLNYYEGETI

Sequences:

>Translated_585_residues
MLYTIIKENTYQDSIVLMLLSNKLSAIDGINKVSIMMGTPANKDIFKSSGLGTDELEKANPNDIVIVIDTNQEEKVSEVK
EEVEAALKGDSASQDRAKDQEAHNWKRAMELANNPNLALISIPGQYAAMEAENALNEGLHVFLFSDNVSKEDEVKLKQKA
HEKGLLVMGPDCGTGIIHGVPLAFTNIVNKGDIGVVGASGTGIQEVTCIIDRLGKGVTNAIGTGGRDLSTEVGATMVLDS
IKALNQDPQVKVITVISKPPAKEVQQKVLNVLRNIEKPVVTLFLGDKPTYQEENIYHAYTLEEAAVVSVQLSNGDKPNFK
PTVAENVNVSLKDSQVGIKGYYSGGTLASEAAVLVKEAFKEEVPEEKKGAYILKTKHHEIIDLGDDIYTQGKPHPMIDPE
KRIEMLETSGNDPETAVIMIDNVIGYGSHDDMANELAPAIKRILANAHQDGRELAVLVTVVGTDKDPQGYEKQIETLKES
GAMICETNDQMVRTAIKLAGGKVEQPVLDIQKFEYTQEDLTVDEKIMSLINTKPSVINIGLKSFTAAVQKSGSECVQFNW
RPIAGGDEKLMKVLQYLNYYEGETI
>Mature_585_residues
MLYTIIKENTYQDSIVLMLLSNKLSAIDGINKVSIMMGTPANKDIFKSSGLGTDELEKANPNDIVIVIDTNQEEKVSEVK
EEVEAALKGDSASQDRAKDQEAHNWKRAMELANNPNLALISIPGQYAAMEAENALNEGLHVFLFSDNVSKEDEVKLKQKA
HEKGLLVMGPDCGTGIIHGVPLAFTNIVNKGDIGVVGASGTGIQEVTCIIDRLGKGVTNAIGTGGRDLSTEVGATMVLDS
IKALNQDPQVKVITVISKPPAKEVQQKVLNVLRNIEKPVVTLFLGDKPTYQEENIYHAYTLEEAAVVSVQLSNGDKPNFK
PTVAENVNVSLKDSQVGIKGYYSGGTLASEAAVLVKEAFKEEVPEEKKGAYILKTKHHEIIDLGDDIYTQGKPHPMIDPE
KRIEMLETSGNDPETAVIMIDNVIGYGSHDDMANELAPAIKRILANAHQDGRELAVLVTVVGTDKDPQGYEKQIETLKES
GAMICETNDQMVRTAIKLAGGKVEQPVLDIQKFEYTQEDLTVDEKIMSLINTKPSVINIGLKSFTAAVQKSGSECVQFNW
RPIAGGDEKLMKVLQYLNYYEGETI

Specific function: Not known; multicopy suppressor of dominant negative ftsH mutations [H]

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yahF and some, to bacterial sucD [H]

Homologues:

Organism=Escherichia coli, GI1786729, Length=584, Percent_Identity=39.554794520548, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1786513, Length=497, Percent_Identity=42.0523138832998, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003781
- InterPro:   IPR005811
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: NA

Molecular weight: Translated: 63765; Mature: 63765

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYTIIKENTYQDSIVLMLLSNKLSAIDGINKVSIMMGTPANKDIFKSSGLGTDELEKAN
CEEEEEECCCCCCCEEEEEHHCCHHHHCCCCEEEEEECCCCCCHHHHCCCCCHHHHHCCC
PNDIVIVIDTNQEEKVSEVKEEVEAALKGDSASQDRAKDQEAHNWKRAMELANNPNLALI
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
SIPGQYAAMEAENALNEGLHVFLFSDNVSKEDEVKLKQKAHEKGLLVMGPDCGTGIIHGV
ECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHCCC
PLAFTNIVNKGDIGVVGASGTGIQEVTCIIDRLGKGVTNAIGTGGRDLSTEVGATMVLDS
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHH
IKALNQDPQVKVITVISKPPAKEVQQKVLNVLRNIEKPVVTLFLGDKPTYQEENIYHAYT
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEE
LEEAAVVSVQLSNGDKPNFKPTVAENVNVSLKDSQVGIKGYYSGGTLASEAAVLVKEAFK
ECCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHH
EEVPEEKKGAYILKTKHHEIIDLGDDIYTQGKPHPMIDPEKRIEMLETSGNDPETAVIMI
HHCCCCCCCEEEEEECCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
DNVIGYGSHDDMANELAPAIKRILANAHQDGRELAVLVTVVGTDKDPQGYEKQIETLKES
ECEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHC
GAMICETNDQMVRTAIKLAGGKVEQPVLDIQKFEYTQEDLTVDEKIMSLINTKPSVINIG
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHCCCCCEEECC
LKSFTAAVQKSGSECVQFNWRPIAGGDEKLMKVLQYLNYYEGETI
HHHHHHHHHCCCCCEEEEECEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLYTIIKENTYQDSIVLMLLSNKLSAIDGINKVSIMMGTPANKDIFKSSGLGTDELEKAN
CEEEEEECCCCCCCEEEEEHHCCHHHHCCCCEEEEEECCCCCCHHHHCCCCCHHHHHCCC
PNDIVIVIDTNQEEKVSEVKEEVEAALKGDSASQDRAKDQEAHNWKRAMELANNPNLALI
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
SIPGQYAAMEAENALNEGLHVFLFSDNVSKEDEVKLKQKAHEKGLLVMGPDCGTGIIHGV
ECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHCCC
PLAFTNIVNKGDIGVVGASGTGIQEVTCIIDRLGKGVTNAIGTGGRDLSTEVGATMVLDS
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHH
IKALNQDPQVKVITVISKPPAKEVQQKVLNVLRNIEKPVVTLFLGDKPTYQEENIYHAYT
HHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEE
LEEAAVVSVQLSNGDKPNFKPTVAENVNVSLKDSQVGIKGYYSGGTLASEAAVLVKEAFK
ECCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHH
EEVPEEKKGAYILKTKHHEIIDLGDDIYTQGKPHPMIDPEKRIEMLETSGNDPETAVIMI
HHCCCCCCCEEEEEECCCCEEECCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEE
DNVIGYGSHDDMANELAPAIKRILANAHQDGRELAVLVTVVGTDKDPQGYEKQIETLKES
ECEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHC
GAMICETNDQMVRTAIKLAGGKVEQPVLDIQKFEYTQEDLTVDEKIMSLINTKPSVINIG
CCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHCCCCCEEECC
LKSFTAAVQKSGSECVQFNWRPIAGGDEKLMKVLQYLNYYEGETI
HHHHHHHHHCCCCCEEEEECEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7500942; 9278503; 3309887 [H]