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The map label for this gene is alr [H]

Identifier: 52784371

GI number: 52784371

Start: 557904

End: 559076

Strand: Direct

Name: alr [H]

Synonym: BLi00551

Alternate gene names: 52784371

Gene position: 557904-559076 (Clockwise)

Preceding gene: 52784370

Following gene: 52784372

Centisome position: 13.21

GC content: 50.9

Gene sequence:

>1173_bases
ATGATGAGCTTAAAACCATTCTATAGAAAGACATGGGCCGAAATCGATTTAACGGCTTTAAAAGAAAACGTCCGCAATAT
GAAGCGGCACATCGGCGAGCATGTCCGCCTGATGGCCGTCGTTAAAGCGAATGCCTACGGACACGGGGATGCACAGGTAG
CGAAGGCGGCTCTTGCAGAAGGGGCGTCCATTCTTGCTGTGGCTTTATTGGATGAAGCGCTTTCGCTGAGGGCGCAGGGG
ATTGAAGAACCGATTCTTGTCCTCGGTGCAGTGCCGACCGAATATGCAAGCATTGCCGCGGAAAAGCGCATTATCGTGAC
TGGCTACTCCGTCGGCTGGCTGAAAGACGTGCTCGGTTTTCTGAATGAGGCCGAAGCTCCTCTTGAATATCATTTGAAGA
TCGACACGGGCATGGGCCGCCTTGGCTGCAAAACGGAAGAAGAGATCAAAGAAATGATGGAGATGACCGAATCGAACGAT
AAGCTCAATTGTACGGGCGTGTTCACTCATTTCGCCACGGCGGACGAAAAGGACACCGATTATTTCAACATGCAGCTTGA
CCGCTTTAAAGAGCTGATCAGCCCCCTCCCGCTTGACCGTTTGATGGTGCATTCGTCAAACAGCGCCGCGGGTCTGCGCT
TCAGGGAACAGCTATTTAATGCCGTCCGCTTCGGCATCGGCATGTACGGTTTGGCGCCGTCAACCGAAATAAAAGACGAG
CTGCCGTTTCGTCTGCGGGAAGTGTTTTCGCTTCATACCGAACTCACCCATGTGAAAAAAATTAAAAAAGGCGAGAGCGT
CAGCTACGGGGCGACATATACAGCTCAGCGCGACGAATGGATCGGGACAGTCCCCGTCGGGTATGCCGACGGATGGCTGA
GGCGCCTGGCCGGAACGGAAGTGCTGATCGACGGAAAACGCCAAAAAATAGCAGGGAGAATCTGCATGGACCAGTTCATG
ATTTCCCTTGCCGAAGAATACCCTGTCGGCACAAAGGTTACCTTGATCGGAAAGCAAAAAGACGAATGGATCTCAGTCGA
CGAAATCGCCCAAAATTTGCAGACGATCAATTATGAAATTACCTGTATGATAAGTTCAAGGGTGCCCCGTATGTTTTTGG
AAAATGGGAGTATAATGGAAATAAGGAATCCGATCTTGCCTGATCAATCCTGA

Upstream 100 bases:

>100_bases
TTTCTTTTGTTCAGGGCTGATGATCCCGTGCAAAATTTCCCTTTCTCCGAACTTTTTAGTATGATGGGAAGGACGAGTGA
AACAAGGAACAGGAAGTGTC

Downstream 100 bases:

>100_bases
AAATTGATGAATTAGCGGAAAAACAACTTTGCTTGCGAAAAGAATAATGATATGATTATGAATGGAATGGATAGAGTGTT
GTATCCGTAAGTTTGGTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MMSLKPFYRKTWAEIDLTALKENVRNMKRHIGEHVRLMAVVKANAYGHGDAQVAKAALAEGASILAVALLDEALSLRAQG
IEEPILVLGAVPTEYASIAAEKRIIVTGYSVGWLKDVLGFLNEAEAPLEYHLKIDTGMGRLGCKTEEEIKEMMEMTESND
KLNCTGVFTHFATADEKDTDYFNMQLDRFKELISPLPLDRLMVHSSNSAAGLRFREQLFNAVRFGIGMYGLAPSTEIKDE
LPFRLREVFSLHTELTHVKKIKKGESVSYGATYTAQRDEWIGTVPVGYADGWLRRLAGTEVLIDGKRQKIAGRICMDQFM
ISLAEEYPVGTKVTLIGKQKDEWISVDEIAQNLQTINYEITCMISSRVPRMFLENGSIMEIRNPILPDQS

Sequences:

>Translated_390_residues
MMSLKPFYRKTWAEIDLTALKENVRNMKRHIGEHVRLMAVVKANAYGHGDAQVAKAALAEGASILAVALLDEALSLRAQG
IEEPILVLGAVPTEYASIAAEKRIIVTGYSVGWLKDVLGFLNEAEAPLEYHLKIDTGMGRLGCKTEEEIKEMMEMTESND
KLNCTGVFTHFATADEKDTDYFNMQLDRFKELISPLPLDRLMVHSSNSAAGLRFREQLFNAVRFGIGMYGLAPSTEIKDE
LPFRLREVFSLHTELTHVKKIKKGESVSYGATYTAQRDEWIGTVPVGYADGWLRRLAGTEVLIDGKRQKIAGRICMDQFM
ISLAEEYPVGTKVTLIGKQKDEWISVDEIAQNLQTINYEITCMISSRVPRMFLENGSIMEIRNPILPDQS
>Mature_390_residues
MMSLKPFYRKTWAEIDLTALKENVRNMKRHIGEHVRLMAVVKANAYGHGDAQVAKAALAEGASILAVALLDEALSLRAQG
IEEPILVLGAVPTEYASIAAEKRIIVTGYSVGWLKDVLGFLNEAEAPLEYHLKIDTGMGRLGCKTEEEIKEMMEMTESND
KLNCTGVFTHFATADEKDTDYFNMQLDRFKELISPLPLDRLMVHSSNSAAGLRFREQLFNAVRFGIGMYGLAPSTEIKDE
LPFRLREVFSLHTELTHVKKIKKGESVSYGATYTAQRDEWIGTVPVGYADGWLRRLAGTEVLIDGKRQKIAGRICMDQFM
ISLAEEYPVGTKVTLIGKQKDEWISVDEIAQNLQTINYEITCMISSRVPRMFLENGSIMEIRNPILPDQS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=365, Percent_Identity=34.7945205479452, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790487, Length=367, Percent_Identity=31.6076294277929, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43744; Mature: 43744

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLKPFYRKTWAEIDLTALKENVRNMKRHIGEHVRLMAVVKANAYGHGDAQVAKAALAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHC
GASILAVALLDEALSLRAQGIEEPILVLGAVPTEYASIAAEKRIIVTGYSVGWLKDVLGF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCEEEEEECCHHHHHHHHHH
LNEAEAPLEYHLKIDTGMGRLGCKTEEEIKEMMEMTESNDKLNCTGVFTHFATADEKDTD
HCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEHCCCCCCCCC
YFNMQLDRFKELISPLPLDRLMVHSSNSAAGLRFREQLFNAVRFGIGMYGLAPSTEIKDE
HHHHHHHHHHHHHCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
LPFRLREVFSLHTELTHVKKIKKGESVSYGATYTAQRDEWIGTVPVGYADGWLRRLAGTE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHCCCE
VLIDGKRQKIAGRICMDQFMISLAEEYPVGTKVTLIGKQKDEWISVDEIAQNLQTINYEI
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEE
TCMISSRVPRMFLENGSIMEIRNPILPDQS
EEEECCCCCHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MMSLKPFYRKTWAEIDLTALKENVRNMKRHIGEHVRLMAVVKANAYGHGDAQVAKAALAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHC
GASILAVALLDEALSLRAQGIEEPILVLGAVPTEYASIAAEKRIIVTGYSVGWLKDVLGF
CHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCEEEEEECCHHHHHHHHHH
LNEAEAPLEYHLKIDTGMGRLGCKTEEEIKEMMEMTESNDKLNCTGVFTHFATADEKDTD
HCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEHCCCCCCCCC
YFNMQLDRFKELISPLPLDRLMVHSSNSAAGLRFREQLFNAVRFGIGMYGLAPSTEIKDE
HHHHHHHHHHHHHCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCC
LPFRLREVFSLHTELTHVKKIKKGESVSYGATYTAQRDEWIGTVPVGYADGWLRRLAGTE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHCCCE
VLIDGKRQKIAGRICMDQFMISLAEEYPVGTKVTLIGKQKDEWISVDEIAQNLQTINYEI
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEE
TCMISSRVPRMFLENGSIMEIRNPILPDQS
EEEECCCCCHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]