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The map label for this gene is yesM [H]

Identifier: 52784260

GI number: 52784260

Start: 436204

End: 437988

Strand: Direct

Name: yesM [H]

Synonym: BLi00440

Alternate gene names: 52784260

Gene position: 436204-437988 (Clockwise)

Preceding gene: 52784259

Following gene: 52784261

Centisome position: 10.33

GC content: 45.83

Gene sequence:

>1785_bases
ATGTGGCAGCCTATTATGCGAATGATTAAACGTTTGATCAATAATGCGCCGATCCGTCATAAGCTGATCAGCCTTCTCTT
GTTAATCAGCATGCTGCCGACGATCGGCCTGGGCATTTTATCGGGATGGGCCGTTGAAAATATTATTGAAAAACAGGTGA
TCGACCAAACACTGCAGCTGATCGGCGAAGTGAACAAGACGGCTGAAGTGTATGTCAGCCACATGCAGAACCTGACATAT
TTAATATCAATGAATGAAGAAATGGAAGCGTTTTTTAGTCATAAAAAGGAGGATGGAGAGGCGGATTATAAGCGAAGGAC
GTTTTTGCAGGGCCTGACTTCTTTATATTCCGAAGCAGCGGGTATTCTCGTTGTCAATGATAAGGGTGAGATGATCAGCA
ATGAGATGTATGAACGCACGCCGACAGATTTGACAAAAGAACCATGGTATCAGGCGGCTCTCGACAATGAAGGGATTTTC
AAGATGATCGGGAAGCCTGTCAACCGGAATATCAGAAGCCATGTGCACTATAGGGAAGATGAGGTCGTTTCCGCCGTCAG
AGCTGTTATCGATCCTGAAACACAGCATGTGAAAGGCGTTGTACTCATCGATTTGAAGCTGCGCGTCCTCGCAGAAGCGA
CAAAAAATATCCGCTTGGGGAAAACGGGTTATTTGATGATCATGGATGAAAATGGCGGCAATATTTATTCGCCGGAGACT
TCGAATCTATTTCTGCCGAAAAAGTGGTTCCGTCAAGAACGTTCTGGATATTTTTCGAAGCGGATCAAGGGAGAGGAATA
TCAGTTCATTTATGAGACGTCTTCCTTTACGAACTGGACGACGGTCGGCGTTTTTAAAGCGGGTGAACCGGTTTTCGAAG
TGAAGGAAATCCACTTGTATGTGCTTTTGTTTTTATTGACGGCGGCGTTTCTCGGAATGTCAGCTTCCTATTATTTGTCC
CATTCCATGTCGCGGCCGATTTTGAAGCTGAATGCTGTCATGAAAACGGCGGAAAGCGGGAATTTTTCAACATTGTATCA
GGAGGAAAGGGAAGATGAAATCGGCCTTTTGGGAAAAAGCTTCAATCGCCTGATGTTCAGAATCCGCGAGCTGATGTCCG
TTACAGAAAGACAGGAGCGCCAAAAAAGAGAAGCCGAATTAAGAGCGCTGCAGGCGCAGATCAACCCTCACTTTCTCTAC
AATACGCTGGATACAATCAATTGGATGGCAAGGAAAAAAGGAGCGGAAGAGGTCAGCGATCTCGTGCAGGCTTTATCCAA
GCTGTTCCGCATTTCCTTGAGCAAAGGGAAAGATATCATCCCGCTGTCTGATGAATTTGAACATGTTGAAAACTATTTGA
AAATCCAAAAAGCGAGATACCGCGATAAATTAAACTACTCAATCGAAATGACCGGGCTTTGTGATGACCGCCTGATTTTG
AAGCTCGTTCTTCAGCCTATCGTCGAAAATGCGATCTATCACGGAATTAAAGAAAAAAAGGGGCCGGGGCATATTGCGAT
CAAAGGCATGGAGGAGGATGGCTCGCTAATCATCAAAATCGAGGATGATGGAGCCGGAATGGATGAAGAGACGCTAAAGC
AAATAACGGATCAATTCAAACACAGGGACGATACAGCGGGCTACGGCATGATCAACGTCCATGAACGGATCGCTCTTACA
TTTGGCGAGCCGTACGGTATAACGGTTGAAAGTCGGAAAGGAGCCGGAACCGCCGTCACGATACGGCTACCAATTTTAGC
AAAAGGGGGAACAAGCCTTGAGTGA

Upstream 100 bases:

>100_bases
TGGTCGCTGCACATGCTGTTTTTCTCAAATCACCATCTGAAGCATGAACGCCCGCTTCCGGCCGCAATCGACACAGGCAT
TACCATCATAACGAAAGAAA

Downstream 100 bases:

>100_bases
ATGTTGGCGCGTACTGATTGCCGATGATGAACCGTGGATTCGGGAAGGAATACGGGATGCCGTCTCTTGGGAGCGCTATC
AAATGTCGGTGTCGGCTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MWQPIMRMIKRLINNAPIRHKLISLLLLISMLPTIGLGILSGWAVENIIEKQVIDQTLQLIGEVNKTAEVYVSHMQNLTY
LISMNEEMEAFFSHKKEDGEADYKRRTFLQGLTSLYSEAAGILVVNDKGEMISNEMYERTPTDLTKEPWYQAALDNEGIF
KMIGKPVNRNIRSHVHYREDEVVSAVRAVIDPETQHVKGVVLIDLKLRVLAEATKNIRLGKTGYLMIMDENGGNIYSPET
SNLFLPKKWFRQERSGYFSKRIKGEEYQFIYETSSFTNWTTVGVFKAGEPVFEVKEIHLYVLLFLLTAAFLGMSASYYLS
HSMSRPILKLNAVMKTAESGNFSTLYQEEREDEIGLLGKSFNRLMFRIRELMSVTERQERQKREAELRALQAQINPHFLY
NTLDTINWMARKKGAEEVSDLVQALSKLFRISLSKGKDIIPLSDEFEHVENYLKIQKARYRDKLNYSIEMTGLCDDRLIL
KLVLQPIVENAIYHGIKEKKGPGHIAIKGMEEDGSLIIKIEDDGAGMDEETLKQITDQFKHRDDTAGYGMINVHERIALT
FGEPYGITVESRKGAGTAVTIRLPILAKGGTSLE

Sequences:

>Translated_594_residues
MWQPIMRMIKRLINNAPIRHKLISLLLLISMLPTIGLGILSGWAVENIIEKQVIDQTLQLIGEVNKTAEVYVSHMQNLTY
LISMNEEMEAFFSHKKEDGEADYKRRTFLQGLTSLYSEAAGILVVNDKGEMISNEMYERTPTDLTKEPWYQAALDNEGIF
KMIGKPVNRNIRSHVHYREDEVVSAVRAVIDPETQHVKGVVLIDLKLRVLAEATKNIRLGKTGYLMIMDENGGNIYSPET
SNLFLPKKWFRQERSGYFSKRIKGEEYQFIYETSSFTNWTTVGVFKAGEPVFEVKEIHLYVLLFLLTAAFLGMSASYYLS
HSMSRPILKLNAVMKTAESGNFSTLYQEEREDEIGLLGKSFNRLMFRIRELMSVTERQERQKREAELRALQAQINPHFLY
NTLDTINWMARKKGAEEVSDLVQALSKLFRISLSKGKDIIPLSDEFEHVENYLKIQKARYRDKLNYSIEMTGLCDDRLIL
KLVLQPIVENAIYHGIKEKKGPGHIAIKGMEEDGSLIIKIEDDGAGMDEETLKQITDQFKHRDDTAGYGMINVHERIALT
FGEPYGITVESRKGAGTAVTIRLPILAKGGTSLE
>Mature_594_residues
MWQPIMRMIKRLINNAPIRHKLISLLLLISMLPTIGLGILSGWAVENIIEKQVIDQTLQLIGEVNKTAEVYVSHMQNLTY
LISMNEEMEAFFSHKKEDGEADYKRRTFLQGLTSLYSEAAGILVVNDKGEMISNEMYERTPTDLTKEPWYQAALDNEGIF
KMIGKPVNRNIRSHVHYREDEVVSAVRAVIDPETQHVKGVVLIDLKLRVLAEATKNIRLGKTGYLMIMDENGGNIYSPET
SNLFLPKKWFRQERSGYFSKRIKGEEYQFIYETSSFTNWTTVGVFKAGEPVFEVKEIHLYVLLFLLTAAFLGMSASYYLS
HSMSRPILKLNAVMKTAESGNFSTLYQEEREDEIGLLGKSFNRLMFRIRELMSVTERQERQKREAELRALQAQINPHFLY
NTLDTINWMARKKGAEEVSDLVQALSKLFRISLSKGKDIIPLSDEFEHVENYLKIQKARYRDKLNYSIEMTGLCDDRLIL
KLVLQPIVENAIYHGIKEKKGPGHIAIKGMEEDGSLIIKIEDDGAGMDEETLKQITDQFKHRDDTAGYGMINVHERIALT
FGEPYGITVESRKGAGTAVTIRLPILAKGGTSLE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=209, Percent_Identity=37.3205741626794, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788723, Length=218, Percent_Identity=33.0275229357798, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67825; Mature: 67825

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQPIMRMIKRLINNAPIRHKLISLLLLISMLPTIGLGILSGWAVENIIEKQVIDQTLQL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEVNKTAEVYVSHMQNLTYLISMNEEMEAFFSHKKEDGEADYKRRTFLQGLTSLYSEAA
HHHHCHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
GILVVNDKGEMISNEMYERTPTDLTKEPWYQAALDNEGIFKMIGKPVNRNIRSHVHYRED
CEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCHHHHCCCCHH
EVVSAVRAVIDPETQHVKGVVLIDLKLRVLAEATKNIRLGKTGYLMIMDENGGNIYSPET
HHHHHHHHHHCCCCHHCCEEEEEEHHHHHHHHHHCCEEECCCEEEEEEECCCCEEECCCC
SNLFLPKKWFRQERSGYFSKRIKGEEYQFIYETSSFTNWTTVGVFKAGEPVFEVKEIHLY
CCEECCHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHH
VLLFLLTAAFLGMSASYYLSHSMSRPILKLNAVMKTAESGNFSTLYQEEREDEIGLLGKS
HHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHH
FNRLMFRIRELMSVTERQERQKREAELRALQAQINPHFLYNTLDTINWMARKKGAEEVSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
LVQALSKLFRISLSKGKDIIPLSDEFEHVENYLKIQKARYRDKLNYSIEMTGLCDDRLIL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KLVLQPIVENAIYHGIKEKKGPGHIAIKGMEEDGSLIIKIEDDGAGMDEETLKQITDQFK
HHHHHHHHHHHHHHCHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHH
HRDDTAGYGMINVHERIALTFGEPYGITVESRKGAGTAVTIRLPILAKGGTSLE
CCCCCCCCCEEEECCEEEEEECCCCEEEEECCCCCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MWQPIMRMIKRLINNAPIRHKLISLLLLISMLPTIGLGILSGWAVENIIEKQVIDQTLQL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGEVNKTAEVYVSHMQNLTYLISMNEEMEAFFSHKKEDGEADYKRRTFLQGLTSLYSEAA
HHHHCHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
GILVVNDKGEMISNEMYERTPTDLTKEPWYQAALDNEGIFKMIGKPVNRNIRSHVHYRED
CEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCHHHHCCCCHH
EVVSAVRAVIDPETQHVKGVVLIDLKLRVLAEATKNIRLGKTGYLMIMDENGGNIYSPET
HHHHHHHHHHCCCCHHCCEEEEEEHHHHHHHHHHCCEEECCCEEEEEEECCCCEEECCCC
SNLFLPKKWFRQERSGYFSKRIKGEEYQFIYETSSFTNWTTVGVFKAGEPVFEVKEIHLY
CCEECCHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHH
VLLFLLTAAFLGMSASYYLSHSMSRPILKLNAVMKTAESGNFSTLYQEEREDEIGLLGKS
HHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHH
FNRLMFRIRELMSVTERQERQKREAELRALQAQINPHFLYNTLDTINWMARKKGAEEVSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHH
LVQALSKLFRISLSKGKDIIPLSDEFEHVENYLKIQKARYRDKLNYSIEMTGLCDDRLIL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
KLVLQPIVENAIYHGIKEKKGPGHIAIKGMEEDGSLIIKIEDDGAGMDEETLKQITDQFK
HHHHHHHHHHHHHHCHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHH
HRDDTAGYGMINVHERIALTFGEPYGITVESRKGAGTAVTIRLPILAKGGTSLE
CCCCCCCCCEEEECCEEEEEECCCCEEEEECCCCCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]