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The map label for this gene is rocF [H]

Identifier: 52784244

GI number: 52784244

Start: 424065

End: 424958

Strand: Direct

Name: rocF [H]

Synonym: BLi00424

Alternate gene names: 52784244

Gene position: 424065-424958 (Clockwise)

Preceding gene: 52784243

Following gene: 52784246

Centisome position: 10.04

GC content: 53.24

Gene sequence:

>894_bases
ATGAATAAACAAGTTTCTTTGATTGGAATGCCGATGGACTTGGGGCAGGCGCGGCGCGGTGTGGATATGGGACCGAGCGC
GATTCGCTACGCTCATATCGTGGAGCGCTTAAACGAGCTGGGCTATGATATCGATGATCTGGGCGATGTGCCGATCAACC
GCGATCAGCCAAAAGGAGACGAAGGGCTGAAAAATTTAGTTTCCGTACTGGAAGGAAACCGCAAGCTGGCCGATATCGTC
GACAATGTCGTCGAGCAGCGCCGCTTCCCGCTCGTGCTGGGCGGAGACCACAGCATTGCCATCGGGACATTGGCGGGTGT
AGCCAAGCATTATCAACAGCTCGGCGTGATTTGGTATGACGCACACGGAGACCTAAATACGCTTGAGACATCGCCGTCAG
GCAACATCCACGGCATGCCGCTGGCGGTAAGTCTCGGTGTCGGCCACGAAAAGCTGGTCAACCTCCACGGCTATGCGCCG
AAAATCAAACCGGAGCACGTCGTCATCATCGGTGCGCGCTCGCTTGATGAAGGAGAGCGCAAATATATCCGTGAAACCGG
CATGAAAGTCTATACCATGCATGAAATTGACAGGCTCGGCATGACGAAGGTAATGGAGGAAACGATCGAGTATTTGTCAG
CAAATTGCGACGGCATCCATCTGAGCCTTGATCTGGACGGTCTTGATCCGAGTGACGCTCCGGGAGTCGGCACCCCTGTC
GTCGGAGGCATCAGCTACAGGGAAAGCCATTTGGCGATGGAAATGCTCTATGACGCAGATATCATTACATCCGCCGAGTT
TGTTGAAGTCAACCCGATACTGGATCATAAAAATAAAACCGGTGAGGCGGCCGTCGAACTGATCGAATCATTGTTAGGGA
AGAAACTGCTGTAA

Upstream 100 bases:

>100_bases
TGCTACTTTGTTTATCACGTGTTTGTGAAAAAACGCCAGGCTCTTGATCGACAAGAAGCAATGATCTATCAAAACAAAAC
AAACGATGAGGTGGTTATTG

Downstream 100 bases:

>100_bases
CCAATGCGAAGGAGAGGGCATCGGCATGATGCCTTCTCTTTTTTTATTGGCGCATTCCCGGGCGCTTATCAAAATAAAGC
CAAAAATTCTCTCACAGGCT

Product: RocF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDIDDLGDVPINRDQPKGDEGLKNLVSVLEGNRKLADIV
DNVVEQRRFPLVLGGDHSIAIGTLAGVAKHYQQLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAP
KIKPEHVVIIGARSLDEGERKYIRETGMKVYTMHEIDRLGMTKVMEETIEYLSANCDGIHLSLDLDGLDPSDAPGVGTPV
VGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTGEAAVELIESLLGKKLL

Sequences:

>Translated_297_residues
MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDIDDLGDVPINRDQPKGDEGLKNLVSVLEGNRKLADIV
DNVVEQRRFPLVLGGDHSIAIGTLAGVAKHYQQLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAP
KIKPEHVVIIGARSLDEGERKYIRETGMKVYTMHEIDRLGMTKVMEETIEYLSANCDGIHLSLDLDGLDPSDAPGVGTPV
VGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTGEAAVELIESLLGKKLL
>Mature_297_residues
MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDIDDLGDVPINRDQPKGDEGLKNLVSVLEGNRKLADIV
DNVVEQRRFPLVLGGDHSIAIGTLAGVAKHYQQLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAP
KIKPEHVVIIGARSLDEGERKYIRETGMKVYTMHEIDRLGMTKVMEETIEYLSANCDGIHLSLDLDGLDPSDAPGVGTPV
VGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTGEAAVELIESLLGKKLL

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=303, Percent_Identity=40.9240924092409, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI4502215, Length=302, Percent_Identity=39.7350993377483, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI37537722, Length=301, Percent_Identity=26.578073089701, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1789306, Length=287, Percent_Identity=24.7386759581882, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=227, Percent_Identity=38.3259911894273, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6325146, Length=322, Percent_Identity=31.055900621118, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24638886, Length=312, Percent_Identity=33.974358974359, Blast_Score=163, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32402; Mature: 32402

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDIDDLGDVPINRDQPKGD
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCH
EGLKNLVSVLEGNRKLADIVDNVVEQRRFPLVLGGDHSIAIGTLAGVAKHYQQLGVIWYD
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEEE
AHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAPKIKPEHVVIIGARSLDEGER
CCCCCCEECCCCCCCCCCCEEEEEECCCHHHHEEECCCCCCCCCCEEEEEECCCCCHHHH
KYIRETGMKVYTMHEIDRLGMTKVMEETIEYLSANCDGIHLSLDLDGLDPSDAPGVGTPV
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCC
VGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTGEAAVELIESLLGKKLL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNKQVSLIGMPMDLGQARRGVDMGPSAIRYAHIVERLNELGYDIDDLGDVPINRDQPKGD
CCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCH
EGLKNLVSVLEGNRKLADIVDNVVEQRRFPLVLGGDHSIAIGTLAGVAKHYQQLGVIWYD
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEEE
AHGDLNTLETSPSGNIHGMPLAVSLGVGHEKLVNLHGYAPKIKPEHVVIIGARSLDEGER
CCCCCCEECCCCCCCCCCCEEEEEECCCHHHHEEECCCCCCCCCCEEEEEECCCCCHHHH
KYIRETGMKVYTMHEIDRLGMTKVMEETIEYLSANCDGIHLSLDLDGLDPSDAPGVGTPV
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCC
VGGISYRESHLAMEMLYDADIITSAEFVEVNPILDHKNKTGEAAVELIESLLGKKLL
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]