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The map label for this gene is rocE [H]

Identifier: 52784243

GI number: 52784243

Start: 422627

End: 424072

Strand: Direct

Name: rocE [H]

Synonym: BLi00423

Alternate gene names: 52784243

Gene position: 422627-424072 (Clockwise)

Preceding gene: 52784242

Following gene: 52784244

Centisome position: 10.01

GC content: 48.06

Gene sequence:

>1446_bases
TTGAATCATGAAAACCGTGAACAATATACACTGAAACGAACGATGAAATCCCGCCATTTGTTTATGATCTCGCTTGGCGG
CGTCATCGGAACCGGCTTTTTTCTCGGAACAGGTTATACGATTAATGAAGCCGGACCGATCGGCGCGATTCTTTCCTATT
TAGCGGGCGGAATGATCATGTATTTTACGATGCTCTGCCTTGGGGAGCTCGCTGTGGCAATGCCGGTTTCAGGCTCTTTT
CAGACGTACGCGACAAAATTTATCGGGCCTGCTACAGGGTTTGCCGTCGGCTGGATCTATTGGCTCGGCTGGTCGGTTAC
TGTTGCTTTGGAATTTTTGTCAGCGGGGCAGCTGATGAAAAGATGGTTTCCCGATGTCGGCGTCTGGATATGGTGCTTGA
TTTTCGGGCTGCTGCTTTTTTCACTCAATGCTTTATCGGCAAAGGCTTTCGGGGAATCGGAATTTTGGCTGTCCGGCATC
AAAATTATCGTCATTCTTCTGTTTATTATTCTCGGCGGAGGCGCGATGTTCGGACTCATCGACTTGAAAGACGGACAGGC
TGCACCGTTCTTTTCCAATCTGATTGGAGACGGAATTTTTCCAAACGGATTCGGCGCGATCTTTATCACGATGATCACCG
TCAACTTTGCCTTTCAGGGGACGGAGCTGATCGGGATCGCGGCGGGGGAAAGCGAAAATCCGGAAAAAACGGTGCCCCGC
TCCATCAAACAGACGGTCTGGCGGACACTGGTGTTTTTCGGCCTGTCCGTATTTGTACTGGCGGGATTGATTCCATGGGA
AAAAGCGGGGGTTGTTGAAAGTCCGTTCGTTGTGGTATTTGAACAAATCGGCATTCCGTATGCCGCCGATCTGATGAACT
TTGTTATTTTAATTGCTTTGTTATCGGTGGCGAATTCGGGCTTGTACGCATCGACGAGGATGCTTTATTCCCTGGCGAAA
GAGGGAATGGCCGCTCAGGCTTTAAGCCGGGTCAATAAAAGAGGTATTCCGATGAATGCGCTTTGGATCACGCTCGGTTT
TGCGGGTTTGTCCCTCATCTCAAGCGTAGTCGCAGCAGAAACGCTCTACATTTGGCTTTTGTCTCTAGCCGGTTTAAGCG
CGCAAGTCGGCTGGATCACGATTACGGTATCACAGCTGCTATTTCGCAGACGATATGTCAAAGAAGGCGGAAAGGTTGAA
GACTTAAAATTTAAAACGCCTCTTTATCCTTATTTGCCGCTGACGGGATTTATTTTAAACAGCGCCGTCCTTGTGAGCCT
CGCTTTTGATTCAGAGCAGAGGATGGCATTGTACTGCGGGATTTTATTCATGTCGGCCTGCTACTTTGTTTATCACGTGT
TTGTGAAAAAACGCCAGGCTCTTGATCGACAAGAAGCAATGATCTATCAAAACAAAACAAACGATGAGGTGGTTATTGAT
GAATAA

Upstream 100 bases:

>100_bases
TGAAATATCAGGAAAATGTTCAGAAGATTTAAAAAATAGTCTATATGTCATAGGGGGAGCTGACATTAGGGAGAATTGAA
ACGGAAGGGGTGAAGGCGGT

Downstream 100 bases:

>100_bases
ACAAGTTTCTTTGATTGGAATGCCGATGGACTTGGGGCAGGCGCGGCGCGGTGTGGATATGGGACCGAGCGCGATTCGCT
ACGCTCATATCGTGGAGCGC

Product: RocE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNHENREQYTLKRTMKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMIMYFTMLCLGELAVAMPVSGSF
QTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQLMKRWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGI
KIIVILLFIILGGGAMFGLIDLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEKTVPR
SIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFVILIALLSVANSGLYASTRMLYSLAK
EGMAAQALSRVNKRGIPMNALWITLGFAGLSLISSVVAAETLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVE
DLKFKTPLYPYLPLTGFILNSAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNKTNDEVVID
E

Sequences:

>Translated_481_residues
MNHENREQYTLKRTMKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMIMYFTMLCLGELAVAMPVSGSF
QTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQLMKRWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGI
KIIVILLFIILGGGAMFGLIDLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEKTVPR
SIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFVILIALLSVANSGLYASTRMLYSLAK
EGMAAQALSRVNKRGIPMNALWITLGFAGLSLISSVVAAETLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVE
DLKFKTPLYPYLPLTGFILNSAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNKTNDEVVID
E
>Mature_481_residues
MNHENREQYTLKRTMKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMIMYFTMLCLGELAVAMPVSGSF
QTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQLMKRWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGI
KIIVILLFIILGGGAMFGLIDLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEKTVPR
SIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFVILIALLSVANSGLYASTRMLYSLAK
EGMAAQALSRVNKRGIPMNALWITLGFAGLSLISSVVAAETLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVE
DLKFKTPLYPYLPLTGFILNSAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNKTNDEVVID
E

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=360, Percent_Identity=23.8888888888889, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI258645169, Length=386, Percent_Identity=24.0932642487047, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=463, Percent_Identity=49.0280777537797, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1788480, Length=487, Percent_Identity=40.041067761807, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786302, Length=437, Percent_Identity=36.1556064073227, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI48994972, Length=464, Percent_Identity=33.4051724137931, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789017, Length=436, Percent_Identity=36.697247706422, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1786789, Length=410, Percent_Identity=36.3414634146341, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1786602, Length=470, Percent_Identity=34.468085106383, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790653, Length=469, Percent_Identity=32.409381663113, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI87081915, Length=479, Percent_Identity=31.5240083507307, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87081869, Length=222, Percent_Identity=27.9279279279279, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=433, Percent_Identity=22.6327944572748, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=471, Percent_Identity=24.416135881104, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=498, Percent_Identity=30.7228915662651, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=33.4916864608076, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6324059, Length=498, Percent_Identity=33.5341365461847, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6324553, Length=432, Percent_Identity=31.4814814814815, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6320717, Length=420, Percent_Identity=31.9047619047619, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324990, Length=466, Percent_Identity=30.2575107296137, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6319824, Length=412, Percent_Identity=31.3106796116505, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322892, Length=413, Percent_Identity=33.6561743341404, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6321629, Length=416, Percent_Identity=31.7307692307692, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6319543, Length=412, Percent_Identity=29.126213592233, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6324924, Length=430, Percent_Identity=30.2325581395349, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6319542, Length=410, Percent_Identity=30.9756097560976, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321053, Length=420, Percent_Identity=30, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320251, Length=415, Percent_Identity=28.9156626506024, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322967, Length=448, Percent_Identity=29.6875, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324981, Length=519, Percent_Identity=27.9383429672447, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6319608, Length=440, Percent_Identity=25.6818181818182, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320364, Length=545, Percent_Identity=24.0366972477064, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24667468, Length=350, Percent_Identity=24, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52917; Mature: 52917

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHENREQYTLKRTMKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMIM
CCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHEECCEEECCCCCHHHHHHHHHHHHHH
YFTMLCLGELAVAMPVSGSFQTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQLMK
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGIKIIVILLFIILGGGAMFGLI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
DLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEKTVPR
ECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHH
SIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFVILIAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
LSVANSGLYASTRMLYSLAKEGMAAQALSRVNKRGIPMNALWITLGFAGLSLISSVVAAE
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVEDLKFKTPLYPYLPLTGFILN
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCEECEEECCCCCCCCHHHHHHHH
SAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNKTNDEVVID
HHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEC
E
C
>Mature Secondary Structure
MNHENREQYTLKRTMKSRHLFMISLGGVIGTGFFLGTGYTINEAGPIGAILSYLAGGMIM
CCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHEECCEEECCCCCHHHHHHHHHHHHHH
YFTMLCLGELAVAMPVSGSFQTYATKFIGPATGFAVGWIYWLGWSVTVALEFLSAGQLMK
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWFPDVGVWIWCLIFGLLLFSLNALSAKAFGESEFWLSGIKIIVILLFIILGGGAMFGLI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
DLKDGQAAPFFSNLIGDGIFPNGFGAIFITMITVNFAFQGTELIGIAAGESENPEKTVPR
ECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCCCCCHHHHHH
SIKQTVWRTLVFFGLSVFVLAGLIPWEKAGVVESPFVVVFEQIGIPYAADLMNFVILIAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
LSVANSGLYASTRMLYSLAKEGMAAQALSRVNKRGIPMNALWITLGFAGLSLISSVVAAE
HHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLYIWLLSLAGLSAQVGWITITVSQLLFRRRYVKEGGKVEDLKFKTPLYPYLPLTGFILN
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCEECEEECCCCCCCCHHHHHHHH
SAVLVSLAFDSEQRMALYCGILFMSACYFVYHVFVKKRQALDRQEAMIYQNKTNDEVVID
HHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]