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The map label for this gene is yclB [H]

Identifier: 52784246

GI number: 52784246

Start: 426021

End: 426590

Strand: Direct

Name: yclB [H]

Synonym: BLi00426

Alternate gene names: 52784246

Gene position: 426021-426590 (Clockwise)

Preceding gene: 52784244

Following gene: 52784247

Centisome position: 10.09

GC content: 52.63

Gene sequence:

>570_bases
ATGAACATCATCGTCGGAATCACGGGCGCGACCGGCGCGGTATTTGGCGTGCGGATGCTGGAGTGGCTGAAGAAAACCGA
CGCAGAGACACACCTTGTCATCTCTCCGTGGGCAGCGGCAACGATCCTGCACGAAACGGGATATACGATGAAAGACGTGG
AAAAGCTCGCATCTTTTACGTATTCCCACAAAGACCAGGCGGCCCGCATTTCAAGCGGTTCCTTTCAAACGGACGGAATG
ATTGTCGCACCGTGCAGTATGAAGACGTTGGCGGGCATCCGCACCGGTATGGCGGATAACCTCTTGACCCGTTCGGCGGA
CGTCATGCTGAAGGAACGGAAAAAGCTCGTTCTGTTAACAAGGGAGACGCCGCTGAACCAGATTCATCTTGAAAACATGC
TTGAGCTGACAAAAATGGGGGCGGTGATCCTGCCGCCGATGCCGGCTTTTTATAATCATCCCCAAAATCTGACCGAAATG
GTCGATCATATCGTATTTCGGACGCTGGACCAATTTGGCATCCATCTGTCTGAAGCGAAGCGCTGGGAAGGTATGAAACA
GGAGAAATAA

Upstream 100 bases:

>100_bases
ACCTTTAGAGTATTATATATAGATTTAACAGATATTTTCAATATGGTAAATAGAGGCGTATCATTTTAACTGAAGCACCA
GGAAGGAAAGGGGGGCGCAT

Downstream 100 bases:

>100_bases
GGAGGATAACAGAATGGCTTATCAAGATTTTAGAGATTTTTTAAATACGCTGAAAAAAGAAGGACAGCTTCTTGAAGTCC
AGGAAGAGGTGAAGCCGGAA

Product: aromatic acid decarboxylase

Products: NA

Alternate protein names: PAD; 4-hydroxybenzoate decarboxylase subunit B; 4-hydroxybenzoate DC; Phenylacrylic acid decarboxylase subunit B; Vanillate decarboxylase subunit B [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNIIVGITGATGAVFGVRMLEWLKKTDAETHLVISPWAAATILHETGYTMKDVEKLASFTYSHKDQAARISSGSFQTDGM
IVAPCSMKTLAGIRTGMADNLLTRSADVMLKERKKLVLLTRETPLNQIHLENMLELTKMGAVILPPMPAFYNHPQNLTEM
VDHIVFRTLDQFGIHLSEAKRWEGMKQEK

Sequences:

>Translated_189_residues
MNIIVGITGATGAVFGVRMLEWLKKTDAETHLVISPWAAATILHETGYTMKDVEKLASFTYSHKDQAARISSGSFQTDGM
IVAPCSMKTLAGIRTGMADNLLTRSADVMLKERKKLVLLTRETPLNQIHLENMLELTKMGAVILPPMPAFYNHPQNLTEM
VDHIVFRTLDQFGIHLSEAKRWEGMKQEK
>Mature_189_residues
MNIIVGITGATGAVFGVRMLEWLKKTDAETHLVISPWAAATILHETGYTMKDVEKLASFTYSHKDQAARISSGSFQTDGM
IVAPCSMKTLAGIRTGMADNLLTRSADVMLKERKKLVLLTRETPLNQIHLENMLELTKMGAVILPPMPAFYNHPQNLTEM
VDHIVFRTLDQFGIHLSEAKRWEGMKQEK

Specific function: Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate, vanillate and salicylate. Is not

COG id: COG0163

COG function: function code H; 3-polyprenyl-4-hydroxybenzoate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyprenyl p-hydroxybenzoate / phenylacrylic acid decarboxylases family [H]

Homologues:

Organism=Escherichia coli, GI1788650, Length=186, Percent_Identity=52.6881720430108, Blast_Score=198, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320746, Length=187, Percent_Identity=56.1497326203209, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003382
- InterPro:   IPR004507 [H]

Pfam domain/function: PF02441 Flavoprotein [H]

EC number: =4.1.1.61 [H]

Molecular weight: Translated: 21142; Mature: 21142

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIVGITGATGAVFGVRMLEWLKKTDAETHLVISPWAAATILHETGYTMKDVEKLASFT
CEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHH
YSHKDQAARISSGSFQTDGMIVAPCSMKTLAGIRTGMADNLLTRSADVMLKERKKLVLLT
HCCCHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEE
RETPLNQIHLENMLELTKMGAVILPPMPAFYNHPQNLTEMVDHIVFRTLDQFGIHLSEAK
CCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
RWEGMKQEK
HHCCCCCCC
>Mature Secondary Structure
MNIIVGITGATGAVFGVRMLEWLKKTDAETHLVISPWAAATILHETGYTMKDVEKLASFT
CEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHH
YSHKDQAARISSGSFQTDGMIVAPCSMKTLAGIRTGMADNLLTRSADVMLKERKKLVLLT
HCCCHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEE
RETPLNQIHLENMLELTKMGAVILPPMPAFYNHPQNLTEMVDHIVFRTLDQFGIHLSEAK
CCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
RWEGMKQEK
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]