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The map label for this gene is rlmH

Identifier: 51894437

GI number: 51894437

Start: 3528739

End: 3529224

Strand: Reverse

Name: rlmH

Synonym: STH3303

Alternate gene names: 51894437

Gene position: 3529224-3528739 (Counterclockwise)

Preceding gene: 51894438

Following gene: 51894435

Centisome position: 98.96

GC content: 67.49

Gene sequence:

>486_bases
TTGCGGATCCGGCTGGTGACGGTGGGCAAGGTGAAGGAGAAGTACCTGCAGGACGGGGTGCAGGAGTACCTGAAGCGGCT
GCGTCCCTACGCCCGGGTGGAGATCGTGACGGTGCCGGACGAGCCGATCCCGGACGGTGCCTCGCCGGCCCAGGAGGCCC
AGGTGATGCAGCGGGAGGGGGAGCGGCTTCTCCGCGCCCTCGACCAGGGTGGCCAGGAGCACGTGGTGGTGCTGGACGGG
CGGGGGAAGAACTTTTCGTCCGAGGAGCTGGCGGCTTTCCTGGCGGAGCGTGCCCTGCACGGGGACGCCAACCTGGCCTT
CGTCATCGGCGGCTCGCTGGGGCTGGACCCGGCGGTGCTGGCCCGCGCGGGCACGACGCTCTCGCTGGGGCGGATGACGT
TCCTGCATCAGATGGTGCCGCTGATTCTGCTGGAGCAAATCTACAGGGCGTTTAAGATTAACCGGGGGGAGAAGTACCAC
AAGTAA

Upstream 100 bases:

>100_bases
GACGTGCAGATGGAGCGGCAGGGAGCGGCGGTGGTCTAGCGGAACACTAGAGGCGGTGCCCGGGAGGGCACCGCCTCATG
CGTGCACGGGAGGTGGCGGC

Downstream 100 bases:

>100_bases
AGTGGCGCAACCATACGACTCGAGAAGACTGATGGAATCGCGGGACGACATCTGGTGCAGCCTGGGTGTCGACCCGCATC
TTGTATTCTGCTGCGGCGTA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRIRLVTVGKVKEKYLQDGVQEYLKRLRPYARVEIVTVPDEPIPDGASPAQEAQVMQREGERLLRALDQGGQEHVVVLDG
RGKNFSSEELAAFLAERALHGDANLAFVIGGSLGLDPAVLARAGTTLSLGRMTFLHQMVPLILLEQIYRAFKINRGEKYH
K

Sequences:

>Translated_161_residues
MRIRLVTVGKVKEKYLQDGVQEYLKRLRPYARVEIVTVPDEPIPDGASPAQEAQVMQREGERLLRALDQGGQEHVVVLDG
RGKNFSSEELAAFLAERALHGDANLAFVIGGSLGLDPAVLARAGTTLSLGRMTFLHQMVPLILLEQIYRAFKINRGEKYH
K
>Mature_161_residues
MRIRLVTVGKVKEKYLQDGVQEYLKRLRPYARVEIVTVPDEPIPDGASPAQEAQVMQREGERLLRALDQGGQEHVVVLDG
RGKNFSSEELAAFLAERALHGDANLAFVIGGSLGLDPAVLARAGTTLSLGRMTFLHQMVPLILLEQIYRAFKINRGEKYH
K

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=161, Percent_Identity=32.2981366459627, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_SYMTH (Q67J66)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_077128.1
- ProteinModelPortal:   Q67J66
- SMR:   Q67J66
- GeneID:   2981469
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3303
- NMPDR:   fig|292459.1.peg.3171
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- BioCyc:   STHE292459:STH3303-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17934; Mature: 17934

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRLVTVGKVKEKYLQDGVQEYLKRLRPYARVEIVTVPDEPIPDGASPAQEAQVMQREG
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ERLLRALDQGGQEHVVVLDGRGKNFSSEELAAFLAERALHGDANLAFVIGGSLGLDPAVL
HHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
ARAGTTLSLGRMTFLHQMVPLILLEQIYRAFKINRGEKYHK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRIRLVTVGKVKEKYLQDGVQEYLKRLRPYARVEIVTVPDEPIPDGASPAQEAQVMQREG
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ERLLRALDQGGQEHVVVLDGRGKNFSSEELAAFLAERALHGDANLAFVIGGSLGLDPAVL
HHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
ARAGTTLSLGRMTFLHQMVPLILLEQIYRAFKINRGEKYHK
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA