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The map label for this gene is fchA [H]

Identifier: 51894325

GI number: 51894325

Start: 3398190

End: 3398837

Strand: Reverse

Name: fchA [H]

Synonym: STH3190

Alternate gene names: 51894325

Gene position: 3398837-3398190 (Counterclockwise)

Preceding gene: 51894326

Following gene: 51894324

Centisome position: 95.31

GC content: 71.91

Gene sequence:

>648_bases
ATGCGCATCGGTGAACAGACGGTCAAGGGGTTCTGCGAGCAGGTGGCGGCCTCGACGCCGGCCCCCGGCGGCGGCACGGT
GGCCGCCGTGGCCGGGGCCATGGGGGCCAGCCTGGTCGCCATGGTGGCGGGCCTGACCCGGGGGCGGGAGAAGTTCCGGG
ACGTGGAGGCGGACATGGCGGCCGCCCAGGAAGCGGGCTTGAAGGAGGCGGAGGCGCTCCTCGGCCTGGCCGACCAGGAC
CAGGCGGCGTTCAACCAGGTGATGGCGGCGTTCGCCCTGCCCAAGGGCACGCCGGAGGAGAAGTCGGCGCGTCGGCAGGC
GGTCCAGGCGGCCTACCGGGAGGCGACCCGCACGCCGCTGGAGACCATGGATCACTGCCTGGCGGTGATGCGGCACGCGC
TGGCGGCGGTGGCCCGGGGCAACCCCAACGCTGCCAGCGACGCGGTGGTGGGGCTCCTGATGGCGTCGGCGGGCTTCGAG
GGGGCCCTGTGGAACGTGGCGATCAACCTCGGCTCCATTACGGATGAAGCCTTCCGTCAGGAGACGCTGGAACAGGTGGA
GCGCATGCGTGCGGAACGGGAGGAGGTGCTGCAGGCCTTCCACAGCCTGGTTCCGGATCCGGTGGTGCGGTTCCTGAAGC
AGCAGTAG

Upstream 100 bases:

>100_bases
CATTCCCTACCACATGGGCATGGGTGTCGTGGCCAAGGTCGTGAAGCGGGGCAGGCTCATTGTGGACGAGGGAAAGGTAC
GCAGGAGGTAGCGGTAGCCC

Downstream 100 bases:

>100_bases
CAGTCCAGCGGAGTGACCAGTGGAGGAGGAACGGACCTTGCTCTCCGACATCGCAATTGCGCAGCGTGCACGGCTTGAAC
CGATCACGAAGGTGGCAGAG

Product: formiminotetrahydrofolate cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRIGEQTVKGFCEQVAASTPAPGGGTVAAVAGAMGASLVAMVAGLTRGREKFRDVEADMAAAQEAGLKEAEALLGLADQD
QAAFNQVMAAFALPKGTPEEKSARRQAVQAAYREATRTPLETMDHCLAVMRHALAAVARGNPNAASDAVVGLLMASAGFE
GALWNVAINLGSITDEAFRQETLEQVERMRAEREEVLQAFHSLVPDPVVRFLKQQ

Sequences:

>Translated_215_residues
MRIGEQTVKGFCEQVAASTPAPGGGTVAAVAGAMGASLVAMVAGLTRGREKFRDVEADMAAAQEAGLKEAEALLGLADQD
QAAFNQVMAAFALPKGTPEEKSARRQAVQAAYREATRTPLETMDHCLAVMRHALAAVARGNPNAASDAVVGLLMASAGFE
GALWNVAINLGSITDEAFRQETLEQVERMRAEREEVLQAFHSLVPDPVVRFLKQQ
>Mature_215_residues
MRIGEQTVKGFCEQVAASTPAPGGGTVAAVAGAMGASLVAMVAGLTRGREKFRDVEADMAAAQEAGLKEAEALLGLADQD
QAAFNQVMAAFALPKGTPEEKSARRQAVQAAYREATRTPLETMDHCLAVMRHALAAVARGNPNAASDAVVGLLMASAGFE
GALWNVAINLGSITDEAFRQETLEQVERMRAEREEVLQAFHSLVPDPVVRFLKQQ

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=191, Percent_Identity=38.7434554973822, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI11140815, Length=191, Percent_Identity=38.7434554973822, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 22749; Mature: 22749

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGEQTVKGFCEQVAASTPAPGGGTVAAVAGAMGASLVAMVAGLTRGREKFRDVEADMA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQEAGLKEAEALLGLADQDQAAFNQVMAAFALPKGTPEEKSARRQAVQAAYREATRTPL
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHH
ETMDHCLAVMRHALAAVARGNPNAASDAVVGLLMASAGFEGALWNVAINLGSITDEAFRQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHH
ETLEQVERMRAEREEVLQAFHSLVPDPVVRFLKQQ
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MRIGEQTVKGFCEQVAASTPAPGGGTVAAVAGAMGASLVAMVAGLTRGREKFRDVEADMA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQEAGLKEAEALLGLADQDQAAFNQVMAAFALPKGTPEEKSARRQAVQAAYREATRTPL
HHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHH
ETMDHCLAVMRHALAAVARGNPNAASDAVVGLLMASAGFEGALWNVAINLGSITDEAFRQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHH
ETLEQVERMRAEREEVLQAFHSLVPDPVVRFLKQQ
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]