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The map label for this gene is mmgC [H]

Identifier: 51893601

GI number: 51893601

Start: 2648548

End: 2649693

Strand: Reverse

Name: mmgC [H]

Synonym: STH2463

Alternate gene names: 51893601

Gene position: 2649693-2648548 (Counterclockwise)

Preceding gene: 51893602

Following gene: 51893600

Centisome position: 74.3

GC content: 66.75

Gene sequence:

>1146_bases
GTGAACTTCTTCCTGACCGAAGAGCAGAACATGGTGCGGCAGGCGATCCGGGAACTGGCGGAAAAGGAGATCGCACCGCG
CTCGGCCGAGTTCAACCGGAAGCACGAGTTCCCCTGGCCGAACTTCAAGCTTCTGGCCGAAAACGGCTACCTGAACATGC
ATCTGCCGGAGCCCTACGGCGGCGGCATGGACTGGGTGAGCTACGCGATCGTCATCGAGGAGCTGGCCCGGGCGTGCGCC
GTTACCGCGGTCATCTACGAGGTGCACTGCTCGCTGCACTCGGAGGCGATCTTCCACTTCGGCAGCGAGGAGCAGAAACA
GAAATACCTGCCGCGCCTGACCCGGGGCGAGATCCTGGGGGCCTACGCCCTCACCGAGCCCGGCGCGGGCTCCGACGCGG
CCGCCATCCGCACCACGGCGATCCGGGACGGCGATTCGTACATCCTCAACGGCGAGAAGACCTTCATCACCAACGGCGGC
CAGGCCGGGCTGTACGTGGTCTTCGCCCGGACCAACCCCGACCCGTCCGTCGGCCACCGGGGCATCTCCGCCTTCCTGGT
GGAGGCCGATACCCCCGGGTTCAGCGTCGGCAAGCCCATGGAGAAGATGGGGCTGCACGCCTCGCACACGACGACGCTGC
ACTTCGAGGACTGCCGGATCCCCGCCTCGCAGCTGCTGGGCAAGGAGGGCGAGGGCTTCAAGATCGCCATGGCGATCCTC
GACCGGGGGCGCATCGGCATCGCCGCCCAGGCGGTGGGCATCACGCAGGCGGCCCTCGAGGACTCGATCAAGTTCGCCAA
GGAGCGGCACACCTTCGGCAAGCCCATCGCCGAGCACCAGGCCATCGCCTGGAAGATCGCGGACATGGCCACCGACCTGG
AAGCCGCCCGGCTCCTGCTCTACCGCGCCGCGTTCCTCATGCAGCAGGGGGTCCGGGCGACGAAGGAAATCTCGATGGCC
AAGCTGTTCGCGTCGGAGATGGCGATGAAGCACACGGTGGAGGCCGTGCAGATCCACGGCGGCTACGGGTACATGCAGGA
GTACCGGGTTGAGCGGCTGATGCGGGAGGCCAAGATCACGCAACTGTACGAGGGCACCAGCGAGATCCAGCGGCTGGTGA
TCTCCCGGGCGCTGCTGCGGGATTGA

Upstream 100 bases:

>100_bases
CCCGCTCCCGGGGCGCTGGCATTGGGCTGCCGAGGGCGTTCCCGGGCGCCGGTTCGGGACGCGGCGGACCCCGAAGCATA
CTGACAAGGAGGCAGGACCC

Downstream 100 bases:

>100_bases
TGTGAGCGGTCGCGGAGGCGAGCCGCGAGGGCGAGCGGTGAGCGCCGACCCGCTGGCTGTGGGGAGGGCCCGCAGGCAGT
GAGCGGTGACCGGTCGTCTT

Product: acyl-CoA dehydrogenase, short-chain specific

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNFFLTEEQNMVRQAIRELAEKEIAPRSAEFNRKHEFPWPNFKLLAENGYLNMHLPEPYGGGMDWVSYAIVIEELARACA
VTAVIYEVHCSLHSEAIFHFGSEEQKQKYLPRLTRGEILGAYALTEPGAGSDAAAIRTTAIRDGDSYILNGEKTFITNGG
QAGLYVVFARTNPDPSVGHRGISAFLVEADTPGFSVGKPMEKMGLHASHTTTLHFEDCRIPASQLLGKEGEGFKIAMAIL
DRGRIGIAAQAVGITQAALEDSIKFAKERHTFGKPIAEHQAIAWKIADMATDLEAARLLLYRAAFLMQQGVRATKEISMA
KLFASEMAMKHTVEAVQIHGGYGYMQEYRVERLMREAKITQLYEGTSEIQRLVISRALLRD

Sequences:

>Translated_381_residues
MNFFLTEEQNMVRQAIRELAEKEIAPRSAEFNRKHEFPWPNFKLLAENGYLNMHLPEPYGGGMDWVSYAIVIEELARACA
VTAVIYEVHCSLHSEAIFHFGSEEQKQKYLPRLTRGEILGAYALTEPGAGSDAAAIRTTAIRDGDSYILNGEKTFITNGG
QAGLYVVFARTNPDPSVGHRGISAFLVEADTPGFSVGKPMEKMGLHASHTTTLHFEDCRIPASQLLGKEGEGFKIAMAIL
DRGRIGIAAQAVGITQAALEDSIKFAKERHTFGKPIAEHQAIAWKIADMATDLEAARLLLYRAAFLMQQGVRATKEISMA
KLFASEMAMKHTVEAVQIHGGYGYMQEYRVERLMREAKITQLYEGTSEIQRLVISRALLRD
>Mature_381_residues
MNFFLTEEQNMVRQAIRELAEKEIAPRSAEFNRKHEFPWPNFKLLAENGYLNMHLPEPYGGGMDWVSYAIVIEELARACA
VTAVIYEVHCSLHSEAIFHFGSEEQKQKYLPRLTRGEILGAYALTEPGAGSDAAAIRTTAIRDGDSYILNGEKTFITNGG
QAGLYVVFARTNPDPSVGHRGISAFLVEADTPGFSVGKPMEKMGLHASHTTTLHFEDCRIPASQLLGKEGEGFKIAMAIL
DRGRIGIAAQAVGITQAALEDSIKFAKERHTFGKPIAEHQAIAWKIADMATDLEAARLLLYRAAFLMQQGVRATKEISMA
KLFASEMAMKHTVEAVQIHGGYGYMQEYRVERLMREAKITQLYEGTSEIQRLVISRALLRD

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=49.7354497354497, Blast_Score=356, Evalue=2e-98,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=43.9153439153439, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=43.9153439153439, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=41.8230563002681, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=38.6842105263158, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=37.597911227154, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI226958414, Length=371, Percent_Identity=37.1967654986523, Blast_Score=255, Evalue=6e-68,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=36.0526315789474, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=37.6404494382022, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=36.0313315926893, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI4557235, Length=383, Percent_Identity=36.0313315926893, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=31.6622691292876, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI38505218, Length=344, Percent_Identity=31.6860465116279, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=31.2328767123288, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI48976061, Length=349, Percent_Identity=30.6590257879656, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI211971008, Length=349, Percent_Identity=30.6590257879656, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI156104864, Length=363, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI156104866, Length=353, Percent_Identity=25.4957507082153, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI218563752, Length=280, Percent_Identity=28.9285714285714, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=32.9015544041451, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=31.9480519480519, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87081702, Length=385, Percent_Identity=26.2337662337662, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082384, Length=272, Percent_Identity=28.6764705882353, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=42.6701570680628, Blast_Score=314, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=41.77545691906, Blast_Score=310, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=40.9448818897638, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=39.6782841823056, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=39.5287958115183, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=38.031914893617, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=36.4864864864865, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=43.2142857142857, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71985184, Length=326, Percent_Identity=38.3435582822086, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=41.2017167381974, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=30.7692307692308, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=30.9782608695652, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=30.2631578947368, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI71985192, Length=262, Percent_Identity=38.9312977099237, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=32.2222222222222, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=33.6099585062241, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17562446, Length=358, Percent_Identity=27.9329608938547, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=31.25, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=275, Percent_Identity=25.8181818181818, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=275, Percent_Identity=25.8181818181818, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=47.3544973544974, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=44.4736842105263, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=45.7671957671958, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=39.3139841688654, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=37.7308707124011, Blast_Score=258, Evalue=4e-69,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=37.1014492753623, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=31.4814814814815, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI45550141, Length=311, Percent_Identity=27.0096463022508, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221473076, Length=311, Percent_Identity=27.0096463022508, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42341; Mature: 42341

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFLTEEQNMVRQAIRELAEKEIAPRSAEFNRKHEFPWPNFKLLAENGYLNMHLPEPYG
CCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCC
GGMDWVSYAIVIEELARACAVTAVIYEVHCSLHSEAIFHFGSEEQKQKYLPRLTRGEILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEE
AYALTEPGAGSDAAAIRTTAIRDGDSYILNGEKTFITNGGQAGLYVVFARTNPDPSVGHR
EEEECCCCCCCCCHHEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCC
GISAFLVEADTPGFSVGKPMEKMGLHASHTTTLHFEDCRIPASQLLGKEGEGFKIAMAIL
CCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEEEC
DRGRIGIAAQAVGITQAALEDSIKFAKERHTFGKPIAEHQAIAWKIADMATDLEAARLLL
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHHHHHHHHHHH
YRAAFLMQQGVRATKEISMAKLFASEMAMKHTVEAVQIHGGYGYMQEYRVERLMREAKIT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHH
QLYEGTSEIQRLVISRALLRD
HHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFFLTEEQNMVRQAIRELAEKEIAPRSAEFNRKHEFPWPNFKLLAENGYLNMHLPEPYG
CCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCC
GGMDWVSYAIVIEELARACAVTAVIYEVHCSLHSEAIFHFGSEEQKQKYLPRLTRGEILG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEE
AYALTEPGAGSDAAAIRTTAIRDGDSYILNGEKTFITNGGQAGLYVVFARTNPDPSVGHR
EEEECCCCCCCCCHHEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCC
GISAFLVEADTPGFSVGKPMEKMGLHASHTTTLHFEDCRIPASQLLGKEGEGFKIAMAIL
CCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCEEEEEEEC
DRGRIGIAAQAVGITQAALEDSIKFAKERHTFGKPIAEHQAIAWKIADMATDLEAARLLL
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEHHHHHHHHHHHHHHH
YRAAFLMQQGVRATKEISMAKLFASEMAMKHTVEAVQIHGGYGYMQEYRVERLMREAKIT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHH
QLYEGTSEIQRLVISRALLRD
HHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]