Click here to switch to the map view.

The map label for this gene is spoVD [H]

Identifier: 51893530

GI number: 51893530

Start: 2576189

End: 2578330

Strand: Reverse

Name: spoVD [H]

Synonym: STH2392

Alternate gene names: 51893530

Gene position: 2578330-2576189 (Counterclockwise)

Preceding gene: 51893531

Following gene: 51893529

Centisome position: 72.3

GC content: 71.43

Gene sequence:

>2142_bases
GTGACGGCCTTGCGGCGGCGCGCGAAGATCCTGCGCTTCGTGCTGACGGCGGTCCTGCTGTTCATGGTCGGCCGCCTCGG
CTGGTTCCACGTGATGGAGGCCGAGGAGGTCCTGGCGCGGGAAGAGGCCCGGCGGCTGCAGGAGGCCTCGCTCGCGCCGG
TGCGCGGGGCGCTGCTGGACCGGAGCGGCCGTCCGCTGGCGGTCTCCATCCCCCAGCGCAACGTGGTCGCCTCGCCCTTC
CACATGGAGGCCCGCAACTTTGCCCGCGTCGCCGAGAGCCTCGCCCCCCTGCTGGGGCAGGACGCCTTCGAGCTGGAGCG
GCTGCTGCGGGAGAACCCCGACTCGCAGTACCTGGTACTGGCCCGGGGCGTGGACCTGGCGACGGCGGAGGAGATCGCCG
GGCTGATGCTTCCCGGCATCTCGCTGGAGGAGACCAGCCAGCGGGTCTATCCCCAGGGTGAGGCCGCCAACCAGATCATC
GGCTATCTGGACGCCGACGGGGTGGGCGTCTACGGGCTGGAGGCGCAGTACGAGGAGGCGCTCCGGGGCAGACCCGGCTT
CGTCCGGGCGGAGCTCACCTACGACAACGCCCCCATCCTGGGCACGGTGCGGAGCAACATCCCCGCCGAGGACGGCTACA
CCGTCATCTCCACCATCGACATCTACCTACAGCGGACCTTCGAAGAGGCGCTGGATGAGGTGATCGCCCGGGAAGACGCG
CGGCGCGCACTGGCGATCGCCATGGACGTGCACACCGGCGAGATCCTGGCCCTGGCCATGCGCCCGGGCGCGGACCTGAG
CGACCGCTCCTCCTGGGTTAAGGAGGACGGGACGCTGGACGTGGAGCGGCTGACCAACTGGGCGGTCACGCCGCTGCCGC
CCGGCTCCAGTTTCAAGACGGTGACCACGGCCATTGCCCTGGAGGAGGGGTTGATCGACCTCACAACCCTCATCCCCGAC
TCGGGGCAGATCGAGATCGATGGCTGGACCATCACCAACTGGGACCGGGTCGTCCACGTGGAGCCGCAGATGCGGACCAT
CGCCCAGCTCCTGCAGACTTCCAGCAACGTCGGGCTGATCCACGTGGGCCAGCGCATCCCCCATGAGACCTTTCAGCGGT
ACCTGCAGGCGTTCGGCTTCACCGAGCCCACCGGCCTCGACTTCCCCCACGAGGCCGCCGCCAACGGCCTGACCAACTGG
GAGGAGAAGCGGGCGATCGACTGGGCCAACATCTACATCGGCCAGCACCTGGAGGTGACGCCGGTACAGATGGTGCGCGC
GGCGGCGGTCTTCGCCAACGGCGGCAAGCTGGTGCGGCCGCACCTGGTGAGCGAGATCCGCGACGCCAACGGCGAGACGG
TGTGGAAGGCCCCGACGGAACCCCTGCGCACCGTGATCAGCGAGCAGACGGCGGCCGAGGTCCGGCAGTTGATGGTCAGC
GTCATCGAGGAGGCTTATACCCAGGCGAAGGTCCCGGGCTACACGGCGGGCGGCAAGACGGGCACGGCGCAGAAGTACGA
GGGCGGCCGGGAGAAGGAGCGGGGCCTGGGCGACTTCCTGGGCTTCGCCCCGGCCACCGAGCCCCGGGTGGCGATGTTCG
TCCTGATCGACGAGCCGAGGCCCCCGGGCTACGGCGGCACCATCGCGGCGCCGCTCTTCGCCAAGCTGATGCCGGAGGTG
CTGCGCGCCCTGGGCGTCCCGCCTGACGATCCCGAGGAGGTCGCGGAGCCGCAGGTGGAGCCGGCCGGGGAGAAGGCGCA
GGAGCCGGCCAGGGTGGCGGTGCCCGACGCCCGGTTCCTGCCGGCGGACTGGGCCCTGCAGCGGCTGCGGGATGCGGGGC
TGCAGCCGAAGGTCTCCGGCGAGGGCAAGGTGGTGACGGCCCAGAAGCCGGCGCCGGGTGCCGAGGCTGCCCCCGGCAGC
GAGGTGGAGCTGACGCTTGGCCCGCTGGGCGGCGAGACCGTGACGGTGCCCGACTTCAGCGGCCTTACCCTGGCGGACGC
CGGCCGGCTCTCCGCCGAGCTGGGCCTCCTGCTGAAGCAGGGGGGCGGCGCCGGGTTCGTGGTGGAGCAGAGTCCGGCCC
CGGGGACCGCCGTGCCGTCCGGCAGCGTGATCACCGTCAGGCTCTCCACGGCCCGCCCCTGA

Upstream 100 bases:

>100_bases
GGAGCTGCAGACCGGCCTCTGGATCCAGGAGCAGCGCCAGCGGTTCGAGCAGGCGGCCCGCCTCTTCCTGAACCTGCTCG
GCTGGACCCTATAGGCGGAG

Downstream 100 bases:

>100_bases
TCCCGGAAATCCGGTCTTGACAGTCGGGATTATGGCGCATAGACTCTAGGTGGCGATCCCGATATTGTTGGTCGGAATTG
GGGGCGGTACACGTGAAGCT

Product: soprulation specific penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MTALRRRAKILRFVLTAVLLFMVGRLGWFHVMEAEEVLAREEARRLQEASLAPVRGALLDRSGRPLAVSIPQRNVVASPF
HMEARNFARVAESLAPLLGQDAFELERLLRENPDSQYLVLARGVDLATAEEIAGLMLPGISLEETSQRVYPQGEAANQII
GYLDADGVGVYGLEAQYEEALRGRPGFVRAELTYDNAPILGTVRSNIPAEDGYTVISTIDIYLQRTFEEALDEVIAREDA
RRALAIAMDVHTGEILALAMRPGADLSDRSSWVKEDGTLDVERLTNWAVTPLPPGSSFKTVTTAIALEEGLIDLTTLIPD
SGQIEIDGWTITNWDRVVHVEPQMRTIAQLLQTSSNVGLIHVGQRIPHETFQRYLQAFGFTEPTGLDFPHEAAANGLTNW
EEKRAIDWANIYIGQHLEVTPVQMVRAAAVFANGGKLVRPHLVSEIRDANGETVWKAPTEPLRTVISEQTAAEVRQLMVS
VIEEAYTQAKVPGYTAGGKTGTAQKYEGGREKERGLGDFLGFAPATEPRVAMFVLIDEPRPPGYGGTIAAPLFAKLMPEV
LRALGVPPDDPEEVAEPQVEPAGEKAQEPARVAVPDARFLPADWALQRLRDAGLQPKVSGEGKVVTAQKPAPGAEAAPGS
EVELTLGPLGGETVTVPDFSGLTLADAGRLSAELGLLLKQGGGAGFVVEQSPAPGTAVPSGSVITVRLSTARP

Sequences:

>Translated_713_residues
MTALRRRAKILRFVLTAVLLFMVGRLGWFHVMEAEEVLAREEARRLQEASLAPVRGALLDRSGRPLAVSIPQRNVVASPF
HMEARNFARVAESLAPLLGQDAFELERLLRENPDSQYLVLARGVDLATAEEIAGLMLPGISLEETSQRVYPQGEAANQII
GYLDADGVGVYGLEAQYEEALRGRPGFVRAELTYDNAPILGTVRSNIPAEDGYTVISTIDIYLQRTFEEALDEVIAREDA
RRALAIAMDVHTGEILALAMRPGADLSDRSSWVKEDGTLDVERLTNWAVTPLPPGSSFKTVTTAIALEEGLIDLTTLIPD
SGQIEIDGWTITNWDRVVHVEPQMRTIAQLLQTSSNVGLIHVGQRIPHETFQRYLQAFGFTEPTGLDFPHEAAANGLTNW
EEKRAIDWANIYIGQHLEVTPVQMVRAAAVFANGGKLVRPHLVSEIRDANGETVWKAPTEPLRTVISEQTAAEVRQLMVS
VIEEAYTQAKVPGYTAGGKTGTAQKYEGGREKERGLGDFLGFAPATEPRVAMFVLIDEPRPPGYGGTIAAPLFAKLMPEV
LRALGVPPDDPEEVAEPQVEPAGEKAQEPARVAVPDARFLPADWALQRLRDAGLQPKVSGEGKVVTAQKPAPGAEAAPGS
EVELTLGPLGGETVTVPDFSGLTLADAGRLSAELGLLLKQGGGAGFVVEQSPAPGTAVPSGSVITVRLSTARP
>Mature_712_residues
TALRRRAKILRFVLTAVLLFMVGRLGWFHVMEAEEVLAREEARRLQEASLAPVRGALLDRSGRPLAVSIPQRNVVASPFH
MEARNFARVAESLAPLLGQDAFELERLLRENPDSQYLVLARGVDLATAEEIAGLMLPGISLEETSQRVYPQGEAANQIIG
YLDADGVGVYGLEAQYEEALRGRPGFVRAELTYDNAPILGTVRSNIPAEDGYTVISTIDIYLQRTFEEALDEVIAREDAR
RALAIAMDVHTGEILALAMRPGADLSDRSSWVKEDGTLDVERLTNWAVTPLPPGSSFKTVTTAIALEEGLIDLTTLIPDS
GQIEIDGWTITNWDRVVHVEPQMRTIAQLLQTSSNVGLIHVGQRIPHETFQRYLQAFGFTEPTGLDFPHEAAANGLTNWE
EKRAIDWANIYIGQHLEVTPVQMVRAAAVFANGGKLVRPHLVSEIRDANGETVWKAPTEPLRTVISEQTAAEVRQLMVSV
IEEAYTQAKVPGYTAGGKTGTAQKYEGGREKERGLGDFLGFAPATEPRVAMFVLIDEPRPPGYGGTIAAPLFAKLMPEVL
RALGVPPDDPEEVAEPQVEPAGEKAQEPARVAVPDARFLPADWALQRLRDAGLQPKVSGEGKVVTAQKPAPGAEAAPGSE
VELTLGPLGGETVTVPDFSGLTLADAGRLSAELGLLLKQGGGAGFVVEQSPAPGTAVPSGSVITVRLSTARP

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=599, Percent_Identity=29.2153589315526, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786854, Length=630, Percent_Identity=23.968253968254, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 76976; Mature: 76845

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALRRRAKILRFVLTAVLLFMVGRLGWFHVMEAEEVLAREEARRLQEASLAPVRGALLD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
RSGRPLAVSIPQRNVVASPFHMEARNFARVAESLAPLLGQDAFELERLLRENPDSQYLVL
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
ARGVDLATAEEIAGLMLPGISLEETSQRVYPQGEAANQIIGYLDADGVGVYGLEAQYEEA
ECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHEEEECCCCCEEEECHHHHHHH
LRGRPGFVRAELTYDNAPILGTVRSNIPAEDGYTVISTIDIYLQRTFEEALDEVIAREDA
HCCCCCEEEEEEEECCCCEEEEHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RRALAIAMDVHTGEILALAMRPGADLSDRSSWVKEDGTLDVERLTNWAVTPLPPGSSFKT
HHEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCHH
VTTAIALEEGLIDLTTLIPDSGQIEIDGWTITNWDRVVHVEPQMRTIAQLLQTSSNVGLI
HHHHHHHHCCCEEEHHCCCCCCEEEECCEEEECCCEEEEECHHHHHHHHHHHCCCCCCEE
HVGQRIPHETFQRYLQAFGFTEPTGLDFPHEAAANGLTNWEEKRAIDWANIYIGQHLEVT
ECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHCCCCEEEEECCCCEEC
PVQMVRAAAVFANGGKLVRPHLVSEIRDANGETVWKAPTEPLRTVISEQTAAEVRQLMVS
HHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VIEEAYTQAKVPGYTAGGKTGTAQKYEGGREKERGLGDFLGFAPATEPRVAMFVLIDEPR
HHHHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHCCHHHHHCCCCCCCCCEEEEEEEECCC
PPGYGGTIAAPLFAKLMPEVLRALGVPPDDPEEVAEPQVEPAGEKAQEPARVAVPDARFL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHCCCCEEECCCCCCC
PADWALQRLRDAGLQPKVSGEGKVVTAQKPAPGAEAAPGSEVELTLGPLGGETVTVPDFS
CHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCC
GLTLADAGRLSAELGLLLKQGGGAGFVVEQSPAPGTAVPSGSVITVRLSTARP
CCEECCCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TALRRRAKILRFVLTAVLLFMVGRLGWFHVMEAEEVLAREEARRLQEASLAPVRGALLD
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
RSGRPLAVSIPQRNVVASPFHMEARNFARVAESLAPLLGQDAFELERLLRENPDSQYLVL
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
ARGVDLATAEEIAGLMLPGISLEETSQRVYPQGEAANQIIGYLDADGVGVYGLEAQYEEA
ECCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHEEEECCCCCEEEECHHHHHHH
LRGRPGFVRAELTYDNAPILGTVRSNIPAEDGYTVISTIDIYLQRTFEEALDEVIAREDA
HCCCCCEEEEEEEECCCCEEEEHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RRALAIAMDVHTGEILALAMRPGADLSDRSSWVKEDGTLDVERLTNWAVTPLPPGSSFKT
HHEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCEEHHHHCCCCCCCCCCCCCCHH
VTTAIALEEGLIDLTTLIPDSGQIEIDGWTITNWDRVVHVEPQMRTIAQLLQTSSNVGLI
HHHHHHHHCCCEEEHHCCCCCCEEEECCEEEECCCEEEEECHHHHHHHHHHHCCCCCCEE
HVGQRIPHETFQRYLQAFGFTEPTGLDFPHEAAANGLTNWEEKRAIDWANIYIGQHLEVT
ECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHCCCCEEEEECCCCEEC
PVQMVRAAAVFANGGKLVRPHLVSEIRDANGETVWKAPTEPLRTVISEQTAAEVRQLMVS
HHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VIEEAYTQAKVPGYTAGGKTGTAQKYEGGREKERGLGDFLGFAPATEPRVAMFVLIDEPR
HHHHHHHHCCCCCCCCCCCCCCCHHCCCCCHHHCCHHHHHCCCCCCCCCEEEEEEEECCC
PPGYGGTIAAPLFAKLMPEVLRALGVPPDDPEEVAEPQVEPAGEKAQEPARVAVPDARFL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHCCCCEEECCCCCCC
PADWALQRLRDAGLQPKVSGEGKVVTAQKPAPGAEAAPGSEVELTLGPLGGETVTVPDFS
CHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEECCCCC
GLTLADAGRLSAELGLLLKQGGGAGFVVEQSPAPGTAVPSGSVITVRLSTARP
CCEECCCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]