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The map label for this gene is pbp-1 [H]

Identifier: 51598400

GI number: 51598400

Start: 133796

End: 135685

Strand: Direct

Name: pbp-1 [H]

Synonym: BG0138

Alternate gene names: 51598400

Gene position: 133796-135685 (Clockwise)

Preceding gene: 51598398

Following gene: 51598411

Centisome position: 14.8

GC content: 28.89

Gene sequence:

>1890_bases
ATGACCAAAAAAATACTTAACAACAAATATCGAATAAAGACAATATTAATAATATCTTTGGGTATAACTTTGCTAACTAT
TTACAAATATTTTACATTAATGGTCTTAAATAACAGCCCAGACAACATTATATCTTTAAAGTCAAATGATATTGTAAGAA
GAGGAACAATTTATGATAGAAATGGCAAACCAATAGCATTCTCTTCAAAGTCCTACTCAATTGGAACAAACCCTCAAAAA
ATAGAAAATATTGTAAATACATCTGAAACTCTTGGCGCAATACTCCAAATTGATTCAAGAATTTTAAAGGAAAAGCTTTC
TTCCAATAAAGGGTTTTTATATATAAAAAGAAAAATAAAAAGAGAAGAGTCAGATTTAATCAAAAGAATTCAAGCTGAAG
GCAGGCTCTCAAACATTGCTTTATATCCTGATTACACAAGAATTTATCCTTTTAGACATGTCACAAGCAATATTACTGGA
TTTGTGGGAACAGATAATCTTGGCCTTGAGGGCATTGAATTTTCTCTAAATAGTATCTTAGTGAAAGATAAAACCAAGCA
ACAATTTTTAAATGAAGAATTAGAAACAAACAACATCTACTTAACAATAGACATGAATATACAACAAGGTGTTAGCAAAA
TAGCTAAAAAATACTTTAAAGAAAATAATCCTGAAAGTTTAATTACTTTAGTAATGGACTCCCAAAATGGAGAAATATTA
TCTATGGTTCAATTCCCTCAATATGATGCAAACTTTTATTCTGAATATCCTGAAGAAATACGAAAAAACCTTTCTTCATC
ATTAACCTATGAGCCTGGAAGCATTAATAAAATTTTTACAGTTGCAATAATATTAGAAAGTGGAAAATTAAATTTAGAAG
AAAAATTTTTAGACAATGGAATATATCAAAAACAATTTCCATCAGGAGAGAAAATTACAATCAAAACCTTAAATCCTCCC
TATAAATACATCGACTCTACAGAGATTTTAATTTATTCATCAAATGTAGGAATAGCTTACATTACTGACAAAGTTAGCAA
TGAATACTTTTACAAAAAACTTTTAGATTTTGGATTTGGAAAAAAAGTTGGATTTCCATTTCCCGGGGAAACAAAAGGGC
TCTTAAATCATTATTCAAAATGGTCAGGAAGAAGTAAAGCTACGATTGGATTTGGACAAGAAATAGGAGTGTCAGCAGTT
CAAATATTACAAGCTGCAAGCATACTAGGCAACAATGGAATAATGTTGAAACCTAGAATAATAAAAAAAATAAGTAACGA
TAAAGAAGAAAGTATTAAAGAGTTTGATAAAGAAGAAATAAAAAGAGCAATATCCAAGAGTTCAGCACAAAAAGTTTTAA
AAATGATGAGAGAAGTTGTAAATAAAGGTGGAATTCCAAACCTTAAAATTAAAAATCTTGACATTTCTGCAAAAAGCGGG
ACATCTCAGGCCATTGATAGAAAAACCGGAAAATACTCAGAAGAAGACTATACATCCTCCATCTTAGCAATATACCCCAC
AGAACAACCAAAATATATTATTTATATTGTATACAGATATCCAAAAAAAATAATATATGGAACAAGAATAGCAGCTCCAA
TGGCAAAAGAAATAATAGAATTTATTGAATATCAACAAAACACAAGCGCATATAAAAAAATCAAAATGCCATCAAAAATC
AAGATTCCTAAAACTGCCGCCAATTATAAAAACAAGGCATACTTGCCAAATTTTATAAATCTTTCCAAAAGAGAAGCAAT
AGACATACTAAAATACTATAAAAACACCATAAAAATCAAAATAAATGGCGCTGGATTTGTCTATAAGCAAAGCATACCTC
CCAATACAAAATTAGAAGACATAGTAGAGCTTGAACTGTATTTAAAATAA

Upstream 100 bases:

>100_bases
TTTTTCAGAATATAATAACATATAATAATATAGATGCAAAAAAAAATGAATAATTTTTTATTTCATATAGTCATAAAATA
ATTTAAGAGGTCCAAAATCA

Downstream 100 bases:

>100_bases
TTAAATAAATAAATTTTTAATTTCATTTTTATAAAAATTTAAAATATAGCTTCGCTTAATATCCATTTTAATCGATATTT
CTTTACCAACTTCAAATGGT

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MTKKILNNKYRIKTILIISLGITLLTIYKYFTLMVLNNSPDNIISLKSNDIVRRGTIYDRNGKPIAFSSKSYSIGTNPQK
IENIVNTSETLGAILQIDSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNIALYPDYTRIYPFRHVTSNITG
FVGTDNLGLEGIEFSLNSILVKDKTKQQFLNEELETNNIYLTIDMNIQQGVSKIAKKYFKENNPESLITLVMDSQNGEIL
SMVQFPQYDANFYSEYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPP
YKYIDSTEILIYSSNVGIAYITDKVSNEYFYKKLLDFGFGKKVGFPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAV
QILQAASILGNNGIMLKPRIIKKISNDKEESIKEFDKEEIKRAISKSSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEYQQNTSAYKKIKMPSKI
KIPKTAANYKNKAYLPNFINLSKREAIDILKYYKNTIKIKINGAGFVYKQSIPPNTKLEDIVELELYLK

Sequences:

>Translated_629_residues
MTKKILNNKYRIKTILIISLGITLLTIYKYFTLMVLNNSPDNIISLKSNDIVRRGTIYDRNGKPIAFSSKSYSIGTNPQK
IENIVNTSETLGAILQIDSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNIALYPDYTRIYPFRHVTSNITG
FVGTDNLGLEGIEFSLNSILVKDKTKQQFLNEELETNNIYLTIDMNIQQGVSKIAKKYFKENNPESLITLVMDSQNGEIL
SMVQFPQYDANFYSEYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPP
YKYIDSTEILIYSSNVGIAYITDKVSNEYFYKKLLDFGFGKKVGFPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAV
QILQAASILGNNGIMLKPRIIKKISNDKEESIKEFDKEEIKRAISKSSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEYQQNTSAYKKIKMPSKI
KIPKTAANYKNKAYLPNFINLSKREAIDILKYYKNTIKIKINGAGFVYKQSIPPNTKLEDIVELELYLK
>Mature_628_residues
TKKILNNKYRIKTILIISLGITLLTIYKYFTLMVLNNSPDNIISLKSNDIVRRGTIYDRNGKPIAFSSKSYSIGTNPQKI
ENIVNTSETLGAILQIDSRILKEKLSSNKGFLYIKRKIKREESDLIKRIQAEGRLSNIALYPDYTRIYPFRHVTSNITGF
VGTDNLGLEGIEFSLNSILVKDKTKQQFLNEELETNNIYLTIDMNIQQGVSKIAKKYFKENNPESLITLVMDSQNGEILS
MVQFPQYDANFYSEYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNGIYQKQFPSGEKITIKTLNPPY
KYIDSTEILIYSSNVGIAYITDKVSNEYFYKKLLDFGFGKKVGFPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQ
ILQAASILGNNGIMLKPRIIKKISNDKEESIKEFDKEEIKRAISKSSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSGT
SQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIEFIEYQQNTSAYKKIKMPSKIK
IPKTAANYKNKAYLPNFINLSKREAIDILKYYKNTIKIKINGAGFVYKQSIPPNTKLEDIVELELYLK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=530, Percent_Identity=26.4150943396226, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1786854, Length=564, Percent_Identity=23.2269503546099, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 71711; Mature: 71580

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKILNNKYRIKTILIISLGITLLTIYKYFTLMVLNNSPDNIISLKSNDIVRRGTIYDR
CCCHHHCCCEEEEEEEEEHHHHHHHHHHHHHEEEEECCCCCCEEEECCCCEEEECEEEEC
NGKPIAFSSKSYSIGTNPQKIENIVNTSETLGAILQIDSRILKEKLSSNKGFLYIKRKIK
CCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
REESDLIKRIQAEGRLSNIALYPDYTRIYPFRHVTSNITGFVGTDNLGLEGIEFSLNSIL
CCHHHHHHHHHHCCCCCEEEECCCHHHCCCHHHHHCCCCEEEECCCCCCCCEEEEEEEEE
VKDKTKQQFLNEELETNNIYLTIDMNIQQGVSKIAKKYFKENNPESLITLVMDSQNGEIL
ECCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
SMVQFPQYDANFYSEYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEEEEEECCCCCHHHHHHCCC
IYQKQFPSGEKITIKTLNPPYKYIDSTEILIYSSNVGIAYITDKVSNEYFYKKLLDFGFG
CCCCCCCCCCEEEEEECCCCHHHCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCC
KKVGFPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQILQAASILGNNGIMLKPRI
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IKKISNDKEESIKEFDKEEIKRAISKSSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
HHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIE
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHH
FIEYQQNTSAYKKIKMPSKIKIPKTAANYKNKAYLPNFINLSKREAIDILKYYKNTIKIK
HHHHCCCCCHHHEECCCCCEECCCHHCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEEEE
INGAGFVYKQSIPPNTKLEDIVELELYLK
ECCCEEEEECCCCCCCCHHHEEEEEEEEC
>Mature Secondary Structure 
TKKILNNKYRIKTILIISLGITLLTIYKYFTLMVLNNSPDNIISLKSNDIVRRGTIYDR
CCHHHCCCEEEEEEEEEHHHHHHHHHHHHHEEEEECCCCCCEEEECCCCEEEECEEEEC
NGKPIAFSSKSYSIGTNPQKIENIVNTSETLGAILQIDSRILKEKLSSNKGFLYIKRKIK
CCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
REESDLIKRIQAEGRLSNIALYPDYTRIYPFRHVTSNITGFVGTDNLGLEGIEFSLNSIL
CCHHHHHHHHHHCCCCCEEEECCCHHHCCCHHHHHCCCCEEEECCCCCCCCEEEEEEEEE
VKDKTKQQFLNEELETNNIYLTIDMNIQQGVSKIAKKYFKENNPESLITLVMDSQNGEIL
ECCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEE
SMVQFPQYDANFYSEYPEEIRKNLSSSLTYEPGSINKIFTVAIILESGKLNLEEKFLDNG
EEEECCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEEEEEECCCCCHHHHHHCCC
IYQKQFPSGEKITIKTLNPPYKYIDSTEILIYSSNVGIAYITDKVSNEYFYKKLLDFGFG
CCCCCCCCCCEEEEEECCCCHHHCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCC
KKVGFPFPGETKGLLNHYSKWSGRSKATIGFGQEIGVSAVQILQAASILGNNGIMLKPRI
CCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEECHHH
IKKISNDKEESIKEFDKEEIKRAISKSSAQKVLKMMREVVNKGGIPNLKIKNLDISAKSG
HHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TSQAIDRKTGKYSEEDYTSSILAIYPTEQPKYIIYIVYRYPKKIIYGTRIAAPMAKEIIE
CHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHEECCHHHHHHHHHHHH
FIEYQQNTSAYKKIKMPSKIKIPKTAANYKNKAYLPNFINLSKREAIDILKYYKNTIKIK
HHHHCCCCCHHHEECCCCCEECCCHHCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEEEE
INGAGFVYKQSIPPNTKLEDIVELELYLK
ECCCEEEEECCCCCCCCHHHEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]