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The map label for this gene is arrD [H]

Identifier: 51596140

GI number: 51596140

Start: 2152172

End: 2152660

Strand: Direct

Name: arrD [H]

Synonym: YPTB1805

Alternate gene names: 51596140

Gene position: 2152172-2152660 (Clockwise)

Preceding gene: 51596139

Following gene: 51596141

Centisome position: 45.36

GC content: 52.15

Gene sequence:

>489_bases
ATGGCAATGTCCCCCGCGTTGCGCAAGAAAGTCATGGGTGCGGCAATCGGCGGTGCAATGGCAATAGCAATCGCCATGGT
GGGCGGCAGCGATGGTCTGGAAGGGCGCGAATATACCCCTTATCGTGATGTGGTTGGCGTGCTAACGGTATGCGATGGTC
ATACCGGCAAAGATATTATTCCCAGCAAACGTTATAGCGATGCTGAATGTGATGCTTTGCTACACCAAGATCTGATCCCC
GTATTTGCCACCATTGACCGCATCGTTAACGTTCCAATGCCTGATTTCCGCAAAGCCGCATTGGCATCATTTGGCTACAA
CGTTGGTATTACTGCAATGACCCATTCAACCATGGTGAAAAAGCTCAACCGTGGCGACACTTCTGGCGCGTGCGATGAGC
TCCGCAGATGGATTAAGGCAGGTGGCAAGGTCTGGAAGGGGTTAGTGAATCGCCGTGAAGTCGAGCGCGAATTATGCCTG
ATGCCATAA

Upstream 100 bases:

>100_bases
TTGGTGTGCTGGGTAGCTTGATGTTTGCTTTCCTAACATTCCTAACCAACCTATATTTCAAGGTGCGCGAAGATAAGCGG
AAAGCGGCGAAGGGGGAATA

Downstream 100 bases:

>100_bases
ACCCCTTATAAATTAGCCAGTAATACCCATTTTTAAGCTGCTTTGGTAACGCTACGTGAAATCTGAATTGCTGGTGTCTG
CCATTACCCCTACTTTTTTC

Product: endolysin (lysis protein) (lysozyme)

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAMSPALRKKVMGAAIGGAMAIAIAMVGGSDGLEGREYTPYRDVVGVLTVCDGHTGKDIIPSKRYSDAECDALLHQDLIP
VFATIDRIVNVPMPDFRKAALASFGYNVGITAMTHSTMVKKLNRGDTSGACDELRRWIKAGGKVWKGLVNRREVERELCL
MP

Sequences:

>Translated_162_residues
MAMSPALRKKVMGAAIGGAMAIAIAMVGGSDGLEGREYTPYRDVVGVLTVCDGHTGKDIIPSKRYSDAECDALLHQDLIP
VFATIDRIVNVPMPDFRKAALASFGYNVGITAMTHSTMVKKLNRGDTSGACDELRRWIKAGGKVWKGLVNRREVERELCL
MP
>Mature_161_residues
AMSPALRKKVMGAAIGGAMAIAIAMVGGSDGLEGREYTPYRDVVGVLTVCDGHTGKDIIPSKRYSDAECDALLHQDLIPV
FATIDRIVNVPMPDFRKAALASFGYNVGITAMTHSTMVKKLNRGDTSGACDELRRWIKAGGKVWKGLVNRREVERELCLM
P

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=161, Percent_Identity=53.416149068323, Blast_Score=166, Evalue=7e-43,
Organism=Escherichia coli, GI1787836, Length=117, Percent_Identity=38.4615384615385, Blast_Score=83, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 17554; Mature: 17423

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMSPALRKKVMGAAIGGAMAIAIAMVGGSDGLEGREYTPYRDVVGVLTVCDGHTGKDII
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
PSKRYSDAECDALLHQDLIPVFATIDRIVNVPMPDFRKAALASFGYNVGITAMTHSTMVK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
KLNRGDTSGACDELRRWIKAGGKVWKGLVNRREVERELCLMP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AMSPALRKKVMGAAIGGAMAIAIAMVGGSDGLEGREYTPYRDVVGVLTVCDGHTGKDII
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
PSKRYSDAECDALLHQDLIPVFATIDRIVNVPMPDFRKAALASFGYNVGITAMTHSTMVK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
KLNRGDTSGACDELRRWIKAGGKVWKGLVNRREVERELCLMP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]