BacMap

Definition	Yersinia pseudotuberculosis IP 32953, complete genome.
Accession	NC_006155
Length	4,744,671

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The map label for this gene is hpaE

Identifier: 51595975

GI number: 51595975

Start: 1990282

End: 1991748

Strand: Direct

Name: hpaE

Synonym: YPTB1639

Alternate gene names: 51595975

Gene position: 1990282-1991748 (Clockwise)

Preceding gene: 51595974

Following gene: 51595976

Centisome position: 41.95

GC content: 52.83

Gene sequence:

>1467_bases
ATGAAGATCGTTAACCATTGGATTGATGGGAAAAATATTACCAGTAAGGACTATTTCACAACAATCAACCCGGCCACTGG
CGAGGTGCTGGCTGACGTGGCAAGCGGGGGGATAAAAGAGATCAACCAAGCCGTTGCTGCCGCGAAAAGTGCTTTCCCTC
ACTGGGCTAACCTGCCGATGAAAGTGCGTGCCCGTCTAATGCGCCGTCTGGGGGAGTTGATTGAGCAACAGATCCCAGAA
ATAGCGCAGATGGAAACGCAGGATACCGGCCTGCCCATTTATCAAACGCAAAATGCCTTGATCCCGCGGGCAGCACATAA
CTTCGAATTTTTTGCCGAAATTTGTCAGCAAATGAATGGCCAGACGTATCCGGTTGACGATCAAATGTTGAATTACACCT
TGGTGCAACCCGTGGGAGTGTGTGCGTTGGTCTCCCCTTGGAATGTCCCTTTTATGACGGCGACCTGGAAGGTCGCGCCT
TGTTTGGCGCTGGGTAACACCGCGATATTGAAAATGTCGGAGCTATCGCCACTGACCGCAGACAAACTGGGTGAACTGGC
CTTAGAGGCGGGTATACCGGCGGGGGTTCTCAACGTGGTACAAGGATATGGGGCCACTGTCGGTGATGCATTGGTATGTC
ATCAGGATGTCCGAGCTATCTCTTTTACCGGCGGCACCGCGACGGGAAACCGCATCATGCAACGTGCCGGGTTGAAAAAA
TACTCCATGGAACTCGGTGGTAAATCCCCGGTACTTATCTTCGACGATGCTGATATCGAACGGGCTATGGATGCGGCGCT
ATTTTCCATCTTCTCTCTCAATGGTGAACGTTGCACGGCGGGTTCGCGCATTTTTATTCAAGAGAGTCTCTATTCGGCAT
TTATTCAACGTTTTGCTGAGCGGGCCAGCCGTTTACGTGTGGGGGACCCACAAGATCTCGACACTCAAGTTGGCGCATTG
ATCAGTAAACCGCATTGGGACAAAGTTTCCGGCTATATCCAGTTGGGGATAGAGGAGGGGGCCACGTTGTTGGCAGGGGG
GCCGGATAAACCCATCGACCTACCTGCTCATCTGCGCGGAGGGCACTTCCTGCGTCCAACGGTGTTGGCCGATGTTGATA
ACCGAATGCGGGTTGCTCAGGAAGAGATTTTTGGACCGGTCGCTTGCCTGATCCCCTTTAAGAATGAAGACGCCGGACTG
CGTTTGGCAAACAGCGTGCCATACGGTCTGGCTGCTTATATCTGGACACAAGACGTCAGCAAAGTGCTGCGTTTGGCCCG
AAGTATTGAAGCCGGCATGGTGTTCGTGAATACCCAGAATGTGCGGGATCTCCGCCAGCCATTTGGCGGCATCAAGGCAT
CGGGAACCGGGCGTGAAGGGGGAAAGTACAGTTTTGATGTTTTTGCTGAAGTGAAAAACGTCTGTATTTCCATGGGGGAG
CATCCGATCCCCCGTTGGGGGATGTAA

Upstream 100 bases:

>100_bases
CGAATGTGGTTCCGGGGGATGAAGTCGTGGTTGAGGTAGATGGTATTGGTTGCCTGCTTAACCGTGTTATCAGCCAAACA
GACTATGAGGATGGATTGCT

Downstream 100 bases:

>100_bases
CAGACATCATCGCCGCGGGTTAAATCGCAATCAATATCAGAGAGGCTTATCCCCTGATAATCGACGGTTTCGTGCGGATT
TTATCAAGAAAACCCACTGA

Product: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: CHMS dehydrogenase [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPMKVRARLMRRLGELIEQQIPE
IAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNGQTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAILKMSELSPLTADKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAERASRLRVGDPQDLDTQVGAL
ISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRGGHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGL
RLANSVPYGLAAYIWTQDVSKVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HPIPRWGM

Sequences:

>Translated_488_residues
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPMKVRARLMRRLGELIEQQIPE
IAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNGQTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAILKMSELSPLTADKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAERASRLRVGDPQDLDTQVGAL
ISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRGGHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGL
RLANSVPYGLAAYIWTQDVSKVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HPIPRWGM
>Mature_488_residues
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPMKVRARLMRRLGELIEQQIPE
IAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNGQTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
CLALGNTAILKMSELSPLTADKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAERASRLRVGDPQDLDTQVGAL
ISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRGGHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGL
RLANSVPYGLAAYIWTQDVSKVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HPIPRWGM

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=478, Percent_Identity=42.6778242677824, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI25777730, Length=482, Percent_Identity=41.0788381742739, Blast_Score=377, Evalue=1e-105,
Organism=Homo sapiens, GI153266822, Length=485, Percent_Identity=39.1752577319588, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI25777732, Length=485, Percent_Identity=39.5876288659794, Blast_Score=361, Evalue=1e-100,
Organism=Homo sapiens, GI25777724, Length=482, Percent_Identity=39.2116182572614, Blast_Score=354, Evalue=8e-98,
Organism=Homo sapiens, GI238814322, Length=483, Percent_Identity=37.888198757764, Blast_Score=345, Evalue=7e-95,
Organism=Homo sapiens, GI21614513, Length=465, Percent_Identity=40.6451612903226, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI115387104, Length=465, Percent_Identity=37.6344086021505, Blast_Score=342, Evalue=6e-94,
Organism=Homo sapiens, GI21361176, Length=485, Percent_Identity=37.5257731958763, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI25777728, Length=419, Percent_Identity=40.0954653937947, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI25952152, Length=478, Percent_Identity=37.2384937238494, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI25777726, Length=479, Percent_Identity=35.6993736951983, Blast_Score=302, Evalue=5e-82,
Organism=Homo sapiens, GI301500698, Length=483, Percent_Identity=34.3685300207039, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI4507229, Length=480, Percent_Identity=35.2083333333333, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI25777721, Length=493, Percent_Identity=34.0770791075051, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI11095441, Length=441, Percent_Identity=29.4784580498866, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI310128093, Length=469, Percent_Identity=25.5863539445629, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI188035924, Length=469, Percent_Identity=25.3731343283582, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI310128103, Length=469, Percent_Identity=25.3731343283582, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI310128091, Length=462, Percent_Identity=26.1904761904762, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI223972651, Length=465, Percent_Identity=27.5268817204301, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI310128089, Length=339, Percent_Identity=28.3185840707965, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI238859541, Length=445, Percent_Identity=26.5168539325843, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI25777736, Length=445, Percent_Identity=26.5168539325843, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI25777734, Length=445, Percent_Identity=26.5168539325843, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557303, Length=342, Percent_Identity=29.5321637426901, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI73466520, Length=343, Percent_Identity=29.4460641399417, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI206597441, Length=451, Percent_Identity=25.0554323725055, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI206597439, Length=451, Percent_Identity=25.0554323725055, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI22907049, Length=451, Percent_Identity=25.0554323725055, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI310128097, Length=252, Percent_Identity=30.952380952381, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI223972653, Length=462, Percent_Identity=24.8917748917749, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI310128095, Length=318, Percent_Identity=27.3584905660377, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI71773324, Length=340, Percent_Identity=27.9411764705882, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI4502043, Length=340, Percent_Identity=27.9411764705882, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI238814371, Length=340, Percent_Identity=27.9411764705882, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI73695881, Length=346, Percent_Identity=25.4335260115607, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI73695879, Length=346, Percent_Identity=25.4335260115607, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI310128087, Length=284, Percent_Identity=22.887323943662, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI310128099, Length=228, Percent_Identity=21.0526315789474, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI310128101, Length=228, Percent_Identity=21.0526315789474, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789015, Length=481, Percent_Identity=38.045738045738, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1786504, Length=470, Percent_Identity=39.5744680851064, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI1787558, Length=468, Percent_Identity=38.4615384615385, Blast_Score=321, Evalue=6e-89,
Organism=Escherichia coli, GI87082295, Length=488, Percent_Identity=36.8852459016393, Blast_Score=318, Evalue=5e-88,
Organism=Escherichia coli, GI87081896, Length=482, Percent_Identity=35.6846473029046, Blast_Score=295, Evalue=7e-81,
Organism=Escherichia coli, GI1787715, Length=459, Percent_Identity=36.1655773420479, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787684, Length=476, Percent_Identity=30.0420168067227, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87081926, Length=468, Percent_Identity=30.982905982906, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1788042, Length=474, Percent_Identity=30.168776371308, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787250, Length=454, Percent_Identity=27.3127753303965, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787653, Length=301, Percent_Identity=26.2458471760797, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144435, Length=482, Percent_Identity=39.4190871369295, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17562198, Length=482, Percent_Identity=38.5892116182573, Blast_Score=352, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI133930964, Length=485, Percent_Identity=37.7319587628866, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI32564736, Length=419, Percent_Identity=39.3794749403341, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI25143876, Length=489, Percent_Identity=36.1963190184049, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI25143874, Length=489, Percent_Identity=36.1963190184049, Blast_Score=323, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI17551164, Length=479, Percent_Identity=37.3695198329854, Blast_Score=321, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=33.9544513457557, Blast_Score=291, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=34.2042755344418, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17534119, Length=475, Percent_Identity=32.6315789473684, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71986308, Length=441, Percent_Identity=31.9727891156463, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI115534176, Length=475, Percent_Identity=24.6315789473684, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17564084, Length=446, Percent_Identity=27.5784753363229, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25146391, Length=445, Percent_Identity=27.1910112359551, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32566756, Length=444, Percent_Identity=27.2522522522523, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI25146394, Length=445, Percent_Identity=27.1910112359551, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17534447, Length=481, Percent_Identity=23.4927234927235, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532534, Length=341, Percent_Identity=25.2199413489736, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=443, Percent_Identity=23.2505643340858, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=319, Percent_Identity=22.884012539185, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324950, Length=480, Percent_Identity=37.9166666666667, Blast_Score=332, Evalue=9e-92,
Organism=Saccharomyces cerevisiae, GI6320917, Length=484, Percent_Identity=37.396694214876, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6323822, Length=479, Percent_Identity=37.3695198329854, Blast_Score=319, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6325196, Length=480, Percent_Identity=36.6666666666667, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6323821, Length=479, Percent_Identity=36.3256784968685, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6319478, Length=477, Percent_Identity=32.0754716981132, Blast_Score=262, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6321828, Length=502, Percent_Identity=25.8964143426295, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321826, Length=495, Percent_Identity=26.0606060606061, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323757, Length=357, Percent_Identity=27.7310924369748, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129399, Length=484, Percent_Identity=41.7355371900826, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24585660, Length=465, Percent_Identity=37.8494623655914, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI281362580, Length=479, Percent_Identity=36.9519832985386, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI62472918, Length=479, Percent_Identity=36.9519832985386, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI62472926, Length=479, Percent_Identity=36.9519832985386, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI62472936, Length=479, Percent_Identity=36.9519832985386, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI21356737, Length=479, Percent_Identity=36.9519832985386, Blast_Score=326, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24650465, Length=482, Percent_Identity=39.6265560165975, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24638878, Length=438, Percent_Identity=31.7351598173516, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24638876, Length=438, Percent_Identity=31.7351598173516, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24666674, Length=478, Percent_Identity=25.9414225941423, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24668425, Length=479, Percent_Identity=26.5135699373695, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24668417, Length=479, Percent_Identity=26.5135699373695, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24668413, Length=479, Percent_Identity=26.5135699373695, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281360303, Length=356, Percent_Identity=25.561797752809, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI45552499, Length=356, Percent_Identity=25.561797752809, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360299, Length=355, Percent_Identity=25.6338028169014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360297, Length=355, Percent_Identity=25.6338028169014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360295, Length=355, Percent_Identity=25.6338028169014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24586250, Length=355, Percent_Identity=25.6338028169014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360301, Length=355, Percent_Identity=25.6338028169014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571806, Length=348, Percent_Identity=24.7126436781609, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571802, Length=348, Percent_Identity=24.7126436781609, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571800, Length=348, Percent_Identity=24.7126436781609, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571798, Length=348, Percent_Identity=24.7126436781609, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571796, Length=348, Percent_Identity=24.7126436781609, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571794, Length=348, Percent_Identity=24.7126436781609, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574525, Length=460, Percent_Identity=21.304347826087, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR011985 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 53165; Mature: 53165

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPM
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCH
KVRARLMRRLGELIEQQIPEIAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNG
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEECCCCCCCCHHCCHHHHHHHHHHHCC
QTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGNTAILKMSELSPLTA
CCCCCCHHHHCEEHHCCCCEEEEECCCCCCEEEECCCHHHHHEECCCCEEEECCCCCCCH
DKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCHH
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAE
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHH
RASRLRVGDPQDLDTQVGALISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRG
HHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCC
GHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGLRLANSVPYGLAAYIWTQDVS
CCEECCHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHH
KVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
HPIPRWGM
CCCCCCCC
>Mature Secondary Structure
MKIVNHWIDGKNITSKDYFTTINPATGEVLADVASGGIKEINQAVAAAKSAFPHWANLPM
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCH
KVRARLMRRLGELIEQQIPEIAQMETQDTGLPIYQTQNALIPRAAHNFEFFAEICQQMNG
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEECCCCCCCCHHCCHHHHHHHHHHHCC
QTYPVDDQMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGNTAILKMSELSPLTA
CCCCCCHHHHCEEHHCCCCEEEEECCCCCCEEEECCCHHHHHEECCCCEEEECCCCCCCH
DKLGELALEAGIPAGVLNVVQGYGATVGDALVCHQDVRAISFTGGTATGNRIMQRAGLKK
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCHH
YSMELGGKSPVLIFDDADIERAMDAALFSIFSLNGERCTAGSRIFIQESLYSAFIQRFAE
HHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEECCCCEEEEHHHHHHHHHHHHHH
RASRLRVGDPQDLDTQVGALISKPHWDKVSGYIQLGIEEGATLLAGGPDKPIDLPAHLRG
HHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCC
GHFLRPTVLADVDNRMRVAQEEIFGPVACLIPFKNEDAGLRLANSVPYGLAAYIWTQDVS
CCEECCHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHH
KVLRLARSIEAGMVFVNTQNVRDLRQPFGGIKASGTGREGGKYSFDVFAEVKNVCISMGE
HHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCC
HPIPRWGM
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]