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The map label for this gene is ywlF [H]

Identifier: 50843759

GI number: 50843759

Start: 2525731

End: 2526213

Strand: Reverse

Name: ywlF [H]

Synonym: PPA2324

Alternate gene names: 50843759

Gene position: 2526213-2525731 (Counterclockwise)

Preceding gene: 50843760

Following gene: 50843758

Centisome position: 98.67

GC content: 59.42

Gene sequence:

>483_bases
ATGGGACTAAGGATCGTTGTCGCCGCTGATCCGGCGGCAGTCGAGTACAAGGATGTCGTCAAGGCTGACCTGGAAGCGGA
TTCGCGAGTCGATGACGTTATCGACGTCGGTGTTCAGGCTGGTGACGACACCCTCTACCCGCACATCGGCATCAAAGGAG
CTCACGTCATCAAAGATGGAAAGGCCGATCGAGGAATCTTCTTCTGCGGCACCGGGATGGGCATGGCCATCACGGCCAAC
AAGGTGCCAGGCATTCGCGCCTGTACCGCCCACGACTCCTTCTCCGTAGAGCGGCTCATCATGTCCAACGACGCCCACGT
GCTATGCCTCGGCCAACGCGTCATCGGTCGCGAACTTGCCCGTCGCTTAGCCCACGAGTTCATCGGGTACACCTTCGACC
CGAGTTCCCACTCCAAGGCCAACATCGATCTCATCGACGCATATGAGTCAGGTGCTGGGGAATCCGCCCCTGGCAACTGC
TGA

Upstream 100 bases:

>100_bases
CTTTTCACATAACCGATGTTAATATGAACGTCATGAGTCGTTGTTGCTCGCAGTTGCGAGTGGGACTCCCCACTACACGG
CAGCGAGACATGGAGGAACC

Downstream 100 bases:

>100_bases
TACCGGGTGGTTCAGACGTGCACCGGCGCACGCTTGAACCACCCCACCCCTGGGCCAACGCCTAGGGTTGCCCAGAAATG
CCGCACCCGTCGCTGCGTGC

Product: ribose 5-phosphate isomerase

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MGLRIVVAADPAAVEYKDVVKADLEADSRVDDVIDVGVQAGDDTLYPHIGIKGAHVIKDGKADRGIFFCGTGMGMAITAN
KVPGIRACTAHDSFSVERLIMSNDAHVLCLGQRVIGRELARRLAHEFIGYTFDPSSHSKANIDLIDAYESGAGESAPGNC

Sequences:

>Translated_160_residues
MGLRIVVAADPAAVEYKDVVKADLEADSRVDDVIDVGVQAGDDTLYPHIGIKGAHVIKDGKADRGIFFCGTGMGMAITAN
KVPGIRACTAHDSFSVERLIMSNDAHVLCLGQRVIGRELARRLAHEFIGYTFDPSSHSKANIDLIDAYESGAGESAPGNC
>Mature_159_residues
GLRIVVAADPAAVEYKDVVKADLEADSRVDDVIDVGVQAGDDTLYPHIGIKGAHVIKDGKADRGIFFCGTGMGMAITANK
VPGIRACTAHDSFSVERLIMSNDAHVLCLGQRVIGRELARRLAHEFIGYTFDPSSHSKANIDLIDAYESGAGESAPGNC

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=119, Percent_Identity=36.1344537815126, Blast_Score=83, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 16971; Mature: 16840

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRIVVAADPAAVEYKDVVKADLEADSRVDDVIDVGVQAGDDTLYPHIGIKGAHVIKDG
CCEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
KADRGIFFCGTGMGMAITANKVPGIRACTAHDSFSVERLIMSNDAHVLCLGQRVIGRELA
CCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEEECCCCEEEEECCHHHHHHHH
RRLAHEFIGYTFDPSSHSKANIDLIDAYESGAGESAPGNC
HHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
GLRIVVAADPAAVEYKDVVKADLEADSRVDDVIDVGVQAGDDTLYPHIGIKGAHVIKDG
CEEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
KADRGIFFCGTGMGMAITANKVPGIRACTAHDSFSVERLIMSNDAHVLCLGQRVIGRELA
CCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEEEECCCCEEEEECCHHHHHHHH
RRLAHEFIGYTFDPSSHSKANIDLIDAYESGAGESAPGNC
HHHHHHHCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]