Click here to switch to the map view.

The map label for this gene is yfdE [H]

Identifier: 50843650

GI number: 50843650

Start: 2399333

End: 2400499

Strand: Reverse

Name: yfdE [H]

Synonym: PPA2215

Alternate gene names: 50843650

Gene position: 2400499-2399333 (Counterclockwise)

Preceding gene: 50843651

Following gene: 50843649

Centisome position: 93.76

GC content: 55.1

Gene sequence:

>1167_bases
GTGTCCAAAGGTGTGCTCGAGGGAGTCAAAGTTCTCGATCTCTCGCGTGTCCTGGCAGGCCCGTACTGCGGTGCTTTCCT
TGCAGATCTAGGTGCTGATGTGGTCAAAGTCGAGGCACCGAATGGTGATGACGCGCGTCATTTGGGACCTTTCAAGGGCG
AGGAGAGCGTATACTTCGCTGAATTGAACCATGGTAAACGGAGCGTCGTCCTGAATTTCAAAGATCCCAAGGACCATGAG
CGTTTCATGAAGCTCGTTGAGCATGCAGACGTCGTGTTAGAAAACTTTCGACCTGGAGTCACGAAGCGTTTGGGAGTGGA
TGCGGAAAGTGTACATAAAACCAATCCGCGAATAATATACGCCAGCATTTCGGGTTTCGGTCAAGAGGGGCCGTTCCGAA
ATCGTCCCGCGTATGATCTCATTGTACAGGCGATGAGCGGAATCATGGCTGCCACGGGTCCTGAAGGAGGAAAGCCGACA
CGCGTTGGTGAATCACTGGGTGACGTCGTTTCAGGGATTTTCGCCGGATGGGCGATTTGTGCAGCACTGTATGAGCGTGA
GCGTACTGGGGTCGGTCGTACTGTCGACGTTTCAATGTTCAATTCTTTGCTTGCGTTGCAGGTGACTAATCTGAGTCTCC
TTCTTGCCGATGGAAAATTGCCGGGACGAATCGGAAATCGTCATCCGGTTTCGGTTCCATTCGACACCTACCCTGCTAAG
GACGGACTGGTTGCCTTGGCAGTGGCAAACGATCGAATTTGGGCACGCTTGGCCGACCTCATGGGAAGGCCGGACCTTGG
TGCCAACGATGCCTATCTCGGTGATATGAACCGCGCGAATAAACGACAAGAGCTCACGCAGTTGGTGTCCGGATGGACGC
AGACGATGACCGTTGCCGAACTGTTGCGGAAGACCGAGGAAGCAGGTGTCCCTGCTGCACCCATCTGGGATCTCAAAGAG
GCGCTTGAAAGTGAGCATGTGGTTGCGCGCCATTCGCTCGGTCACTTCACACACCCGGAGCTCGGAAAGATGCCGTACCT
ACGATTTCCGGCGGACTTCGGGTGCGGCAATCTGGAGGTGTCCTCGGAGTCGTCGCCGCGTTTGGGTGAACAGACAGCAG
GAGCCGTCGCCGCTGAATGGGGCCGATCGGCGAATGACGACAAATGA

Upstream 100 bases:

>100_bases
GAGGGCACGAACCAGATCCAACGGATCGTTATCGCGCGTCAGCTGTTTAACCGGTCACGCTGACGTCTGTGTCCGGGATG
AGTAAGAAAGGAACTTGATC

Downstream 100 bases:

>100_bases
ATGTCTGACGTGGAGTACGTGAAGTTCGCGGGAGTTCTGTCTGCCATCCGCTAAGTGACTGATGACCAAATCGGACCGAT
ATTATGTGTCGGCCAGAAGG

Product: putative L-carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSKGVLEGVKVLDLSRVLAGPYCGAFLADLGADVVKVEAPNGDDARHLGPFKGEESVYFAELNHGKRSVVLNFKDPKDHE
RFMKLVEHADVVLENFRPGVTKRLGVDAESVHKTNPRIIYASISGFGQEGPFRNRPAYDLIVQAMSGIMAATGPEGGKPT
RVGESLGDVVSGIFAGWAICAALYERERTGVGRTVDVSMFNSLLALQVTNLSLLLADGKLPGRIGNRHPVSVPFDTYPAK
DGLVALAVANDRIWARLADLMGRPDLGANDAYLGDMNRANKRQELTQLVSGWTQTMTVAELLRKTEEAGVPAAPIWDLKE
ALESEHVVARHSLGHFTHPELGKMPYLRFPADFGCGNLEVSSESSPRLGEQTAGAVAAEWGRSANDDK

Sequences:

>Translated_388_residues
MSKGVLEGVKVLDLSRVLAGPYCGAFLADLGADVVKVEAPNGDDARHLGPFKGEESVYFAELNHGKRSVVLNFKDPKDHE
RFMKLVEHADVVLENFRPGVTKRLGVDAESVHKTNPRIIYASISGFGQEGPFRNRPAYDLIVQAMSGIMAATGPEGGKPT
RVGESLGDVVSGIFAGWAICAALYERERTGVGRTVDVSMFNSLLALQVTNLSLLLADGKLPGRIGNRHPVSVPFDTYPAK
DGLVALAVANDRIWARLADLMGRPDLGANDAYLGDMNRANKRQELTQLVSGWTQTMTVAELLRKTEEAGVPAAPIWDLKE
ALESEHVVARHSLGHFTHPELGKMPYLRFPADFGCGNLEVSSESSPRLGEQTAGAVAAEWGRSANDDK
>Mature_387_residues
SKGVLEGVKVLDLSRVLAGPYCGAFLADLGADVVKVEAPNGDDARHLGPFKGEESVYFAELNHGKRSVVLNFKDPKDHER
FMKLVEHADVVLENFRPGVTKRLGVDAESVHKTNPRIIYASISGFGQEGPFRNRPAYDLIVQAMSGIMAATGPEGGKPTR
VGESLGDVVSGIFAGWAICAALYERERTGVGRTVDVSMFNSLLALQVTNLSLLLADGKLPGRIGNRHPVSVPFDTYPAKD
GLVALAVANDRIWARLADLMGRPDLGANDAYLGDMNRANKRQELTQLVSGWTQTMTVAELLRKTEEAGVPAAPIWDLKEA
LESEHVVARHSLGHFTHPELGKMPYLRFPADFGCGNLEVSSESSPRLGEQTAGAVAAEWGRSANDDK

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=350, Percent_Identity=36.2857142857143, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI300863124, Length=343, Percent_Identity=37.3177842565598, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI13376042, Length=343, Percent_Identity=34.9854227405248, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI300863126, Length=350, Percent_Identity=32.5714285714286, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI266458393, Length=196, Percent_Identity=36.734693877551, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI266458397, Length=196, Percent_Identity=36.734693877551, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI42794625, Length=196, Percent_Identity=36.734693877551, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI266456254, Length=196, Percent_Identity=36.734693877551, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI42822893, Length=143, Percent_Identity=39.1608391608392, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI266458395, Length=143, Percent_Identity=39.1608391608392, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI87082093, Length=333, Percent_Identity=39.6396396396396, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788717, Length=408, Percent_Identity=29.656862745098, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786222, Length=342, Percent_Identity=24.8538011695906, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564160, Length=197, Percent_Identity=29.9492385786802, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115535051, Length=198, Percent_Identity=29.2929292929293, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24648431, Length=371, Percent_Identity=33.4231805929919, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24585488, Length=332, Percent_Identity=30.1204819277108, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 41912; Mature: 41781

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGVLEGVKVLDLSRVLAGPYCGAFLADLGADVVKVEAPNGDDARHLGPFKGEESVYFA
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
ELNHGKRSVVLNFKDPKDHERFMKLVEHADVVLENFRPGVTKRLGVDAESVHKTNPRIIY
EECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCEEEE
ASISGFGQEGPFRNRPAYDLIVQAMSGIMAATGPEGGKPTRVGESLGDVVSGIFAGWAIC
EEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AALYERERTGVGRTVDVSMFNSLLALQVTNLSLLLADGKLPGRIGNRHPVSVPFDTYPAK
HHHHHHHHCCCCCEEEHHHHHHHHHHEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
DGLVALAVANDRIWARLADLMGRPDLGANDAYLGDMNRANKRQELTQLVSGWTQTMTVAE
CCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLRKTEEAGVPAAPIWDLKEALESEHVVARHSLGHFTHPELGKMPYLRFPADFGCGNLEV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEE
SSESSPRLGEQTAGAVAAEWGRSANDDK
CCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKGVLEGVKVLDLSRVLAGPYCGAFLADLGADVVKVEAPNGDDARHLGPFKGEESVYFA
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
ELNHGKRSVVLNFKDPKDHERFMKLVEHADVVLENFRPGVTKRLGVDAESVHKTNPRIIY
EECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCEEEE
ASISGFGQEGPFRNRPAYDLIVQAMSGIMAATGPEGGKPTRVGESLGDVVSGIFAGWAIC
EEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AALYERERTGVGRTVDVSMFNSLLALQVTNLSLLLADGKLPGRIGNRHPVSVPFDTYPAK
HHHHHHHHCCCCCEEEHHHHHHHHHHEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
DGLVALAVANDRIWARLADLMGRPDLGANDAYLGDMNRANKRQELTQLVSGWTQTMTVAE
CCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLRKTEEAGVPAAPIWDLKEALESEHVVARHSLGHFTHPELGKMPYLRFPADFGCGNLEV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEE
SSESSPRLGEQTAGAVAAEWGRSANDDK
CCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]