Click here to switch to the map view.

The map label for this gene is fadE25 [H]

Identifier: 50843651

GI number: 50843651

Start: 2400537

End: 2401685

Strand: Reverse

Name: fadE25 [H]

Synonym: PPA2216

Alternate gene names: 50843651

Gene position: 2401685-2400537 (Counterclockwise)

Preceding gene: 50843652

Following gene: 50843650

Centisome position: 93.81

GC content: 55.44

Gene sequence:

>1149_bases
ATGCTGTATCACTTGTCAGAAGAGCATGAAATGCTGCGCCAGTTTGTTCGAGAATTCGCTGAGTCGCAGCTTGCTCCCAA
CGCTGCAGAAGTCGACGATAAAGGAGTTTTTGCGCAGCAGCAGTATGATGCTCTCGTTGAGGCGGGTTTCGCGGCTCCTG
GAATCCCAGAGCAGTATGGTGGCGACGGTGCGGATGCGATTGCGTCCGCAATAATCATGGAAGAGGTCGCTCGAGTCTGT
GCGTCGTCGTCCACCGTCATATCGTCCAATGAGCTTGGTACCGTCCCCCTTCTCAAATACGGTAGCGAGGAGCAGAGGAA
ACGTTATCTTTCTGAAGTTGCGTCGGGTAAGGCGCTTTTCGGATATGCGCTCTCCGAGGCTGATGCTGGATCAGATCCAG
CTGCACTAAAGTGTCGAGCCGACGAAGATGGGGACAGTTTCGTCCTGAACGGTGTCAAGGCTTGGGTCACGGAGGCTGGC
GAGGCCAAGTACCTGGTGGTATTTGCGGTTACTGACCCAGACGATCCGCGCCACAGAATCAGCGCGTTGATGGTCCATGC
AGATGACCCGGGCATTAGCTACGGGGCTCCGGAGCACAAAATGGGGATACGCGGGTCAGTTACCAGGGAAGTGGTTTTCA
AGAATACGCGTATCCCCAAGGAACGAGTAATTGGCCGTCGAGGGCACGGTCTGAGTGTTGCTTTGGGTACGCTTGACAAC
TCTCGTGTCTCGATTGCTGCTCAAGCAGTGGGAATTGCCCAGGGAGCTTTAGACATTGCCACGGATTACGTCCAGAAGCG
CAAGCAGTTTGGCCAGCCACTATCCAATTTTGAGGGAATCCAATTCATGCTCGCAGACATGGCAATGCGTTTGGAGGCGG
CGCGAGCGCTGACATACTCTGCAGCTGATCGTAGTGGGCGCCAGACTGACGATGTGAGTTACTTCGGCGCGGCGGCCAAA
TGTTTCGCTTCCGACACAGCGATGGCAGTGTGCACAGATGCAGTCCAGCTGCTCGGTGGCATCGGCTATTCCAAGGATTC
TGCTGTCGAGCGGATGTTCCGAGACGCCAAGGTGACACAGATCTACGAGGGCACGAACCAGATCCAACGGATCGTTATCG
CGCGTCAGCTGTTTAACCGGTCACGCTGA

Upstream 100 bases:

>100_bases
TATTGCGTGCTTTCGATGCTGCTTAGTATCTTGCTTTTTGTAAGAGAACTGCTGAAAGCAATGAAGCCGGAAGCGCGATC
GATAATGATGTGGAGTCAGA

Downstream 100 bases:

>100_bases
CGTCTGTGTCCGGGATGAGTAAGAAAGGAACTTGATCGTGTCCAAAGGTGTGCTCGAGGGAGTCAAAGTTCTCGATCTCT
CGCGTGTCCTGGCAGGCCCG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MLYHLSEEHEMLRQFVREFAESQLAPNAAEVDDKGVFAQQQYDALVEAGFAAPGIPEQYGGDGADAIASAIIMEEVARVC
ASSSTVISSNELGTVPLLKYGSEEQRKRYLSEVASGKALFGYALSEADAGSDPAALKCRADEDGDSFVLNGVKAWVTEAG
EAKYLVVFAVTDPDDPRHRISALMVHADDPGISYGAPEHKMGIRGSVTREVVFKNTRIPKERVIGRRGHGLSVALGTLDN
SRVSIAAQAVGIAQGALDIATDYVQKRKQFGQPLSNFEGIQFMLADMAMRLEAARALTYSAADRSGRQTDDVSYFGAAAK
CFASDTAMAVCTDAVQLLGGIGYSKDSAVERMFRDAKVTQIYEGTNQIQRIVIARQLFNRSR

Sequences:

>Translated_382_residues
MLYHLSEEHEMLRQFVREFAESQLAPNAAEVDDKGVFAQQQYDALVEAGFAAPGIPEQYGGDGADAIASAIIMEEVARVC
ASSSTVISSNELGTVPLLKYGSEEQRKRYLSEVASGKALFGYALSEADAGSDPAALKCRADEDGDSFVLNGVKAWVTEAG
EAKYLVVFAVTDPDDPRHRISALMVHADDPGISYGAPEHKMGIRGSVTREVVFKNTRIPKERVIGRRGHGLSVALGTLDN
SRVSIAAQAVGIAQGALDIATDYVQKRKQFGQPLSNFEGIQFMLADMAMRLEAARALTYSAADRSGRQTDDVSYFGAAAK
CFASDTAMAVCTDAVQLLGGIGYSKDSAVERMFRDAKVTQIYEGTNQIQRIVIARQLFNRSR
>Mature_382_residues
MLYHLSEEHEMLRQFVREFAESQLAPNAAEVDDKGVFAQQQYDALVEAGFAAPGIPEQYGGDGADAIASAIIMEEVARVC
ASSSTVISSNELGTVPLLKYGSEEQRKRYLSEVASGKALFGYALSEADAGSDPAALKCRADEDGDSFVLNGVKAWVTEAG
EAKYLVVFAVTDPDDPRHRISALMVHADDPGISYGAPEHKMGIRGSVTREVVFKNTRIPKERVIGRRGHGLSVALGTLDN
SRVSIAAQAVGIAQGALDIATDYVQKRKQFGQPLSNFEGIQFMLADMAMRLEAARALTYSAADRSGRQTDDVSYFGAAAK
CFASDTAMAVCTDAVQLLGGIGYSKDSAVERMFRDAKVTQIYEGTNQIQRIVIARQLFNRSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=45.1697127937337, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=39.3782383419689, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=39.3782383419689, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=37.6657824933687, Blast_Score=272, Evalue=3e-73,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=35.5614973262032, Blast_Score=248, Evalue=8e-66,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=33.7730870712401, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=34.1207349081365, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=32.2077922077922, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=32.2077922077922, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI226958414, Length=371, Percent_Identity=33.6927223719677, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=29.4429708222812, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=27.8947368421053, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI7669494, Length=366, Percent_Identity=27.8688524590164, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI211971008, Length=338, Percent_Identity=30.4733727810651, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI48976061, Length=338, Percent_Identity=30.4733727810651, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI38505218, Length=328, Percent_Identity=27.1341463414634, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156104866, Length=321, Percent_Identity=23.98753894081, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI156104864, Length=321, Percent_Identity=23.98753894081, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=29.3963254593176, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=28.4237726098191, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082384, Length=295, Percent_Identity=26.7796610169492, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081702, Length=369, Percent_Identity=26.5582655826558, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=40.7792207792208, Blast_Score=299, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=39.5348837209302, Blast_Score=288, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=39.4736842105263, Blast_Score=286, Evalue=9e-78,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=38.6666666666667, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=36.6492146596859, Blast_Score=257, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=35.9580052493438, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=32.8767123287671, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71985184, Length=339, Percent_Identity=32.4483775811209, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=35.3356890459364, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=38.135593220339, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=30.0791556728232, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=28.4960422163588, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=277, Percent_Identity=30.6859205776173, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=27.4611398963731, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=272, Percent_Identity=31.6176470588235, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=28.8617886178862, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=332, Percent_Identity=25.6024096385542, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=43.5828877005348, Blast_Score=310, Evalue=8e-85,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=37.0757180156658, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=41.1764705882353, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=34.9333333333333, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=34.7150259067358, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=34.6820809248555, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI19920834, Length=382, Percent_Identity=28.7958115183246, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI221473076, Length=315, Percent_Identity=24.1269841269841, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550141, Length=315, Percent_Identity=24.1269841269841, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41284; Mature: 41284

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLSEEHEMLRQFVREFAESQLAPNAAEVDDKGVFAQQQYDALVEAGFAAPGIPEQYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHC
GDGADAIASAIIMEEVARVCASSSTVISSNELGTVPLLKYGSEEQRKRYLSEVASGKALF
CCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCEEE
GYALSEADAGSDPAALKCRADEDGDSFVLNGVKAWVTEAGEAKYLVVFAVTDPDDPRHRI
HHHHHCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHE
SALMVHADDPGISYGAPEHKMGIRGSVTREVVFKNTRIPKERVIGRRGHGLSVALGTLDN
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCC
SRVSIAAQAVGIAQGALDIATDYVQKRKQFGQPLSNFEGIQFMLADMAMRLEAARALTYS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AADRSGRQTDDVSYFGAAAKCFASDTAMAVCTDAVQLLGGIGYSKDSAVERMFRDAKVTQ
HHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IYEGTNQIQRIVIARQLFNRSR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYHLSEEHEMLRQFVREFAESQLAPNAAEVDDKGVFAQQQYDALVEAGFAAPGIPEQYG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHC
GDGADAIASAIIMEEVARVCASSSTVISSNELGTVPLLKYGSEEQRKRYLSEVASGKALF
CCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCHHHHHHHHHHHHCCCEEE
GYALSEADAGSDPAALKCRADEDGDSFVLNGVKAWVTEAGEAKYLVVFAVTDPDDPRHRI
HHHHHCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHE
SALMVHADDPGISYGAPEHKMGIRGSVTREVVFKNTRIPKERVIGRRGHGLSVALGTLDN
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCC
SRVSIAAQAVGIAQGALDIATDYVQKRKQFGQPLSNFEGIQFMLADMAMRLEAARALTYS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AADRSGRQTDDVSYFGAAAKCFASDTAMAVCTDAVQLLGGIGYSKDSAVERMFRDAKVTQ
HHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IYEGTNQIQRIVIARQLFNRSR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]