Click here to switch to the map view.

The map label for this gene is 50843602

Identifier: 50843602

GI number: 50843602

Start: 2345736

End: 2346149

Strand: Direct

Name: 50843602

Synonym: PPA2165

Alternate gene names: NA

Gene position: 2345736-2346149 (Clockwise)

Preceding gene: 50843600

Following gene: 50843603

Centisome position: 91.62

GC content: 58.21

Gene sequence:

>414_bases
ATGTACGACAACAGCAGCACTACCGCAGCTATGACGATCAAACTCGACGCCGAGTTCCCCCCTGACCCGGTTTTCGAACC
CGGTATCCGTCGAGCCCCATCGCGTGGATTCCACCTCACCCCCGATCAGACCAAGATCGCGCTGCGCAATGCTCTGCGTT
ATCTACCCCCGGAGTTGCACGAGAAGGCTGTTCCGGAGTTCCTCGAGGAATTGCGTACGTATGGCCGCATCTACGCTTAC
CGGTGGCGTCCAGCCGGGCATATCAAGGGACGCCCAATCGACGATTACGAGGGTCGTTGTACCGAGGGCAAGGCCTTCCA
GGTGCAGATTGACAATAACCTCGACTTCGACGTCGCCCTCTATCCCTACGAACTCGTCACCTATGGCGAGACCGGTAGCG
TCTGCCAGAATTAG

Upstream 100 bases:

>100_bases
CGATCACACCGACGCGATTCTCCCATGGCAATTGTGTGTGCGACCTCGCCAGGATCGTCACGCCACAACGACACCAAGAA
TGTATTGGGGGAAGCAAACG

Downstream 100 bases:

>100_bases
CTGCAGTACCGGCTCATCAAGAAATACCTCTCCCAGCTCACCGAGGACACCACCTTGGTCGTCATGAGCGGTCACCCGCT
GGGGCTTTTCCCGTCGCGCC

Product: urocanate hydratase fragment

Products: urocanate; H2O

Alternate protein names: Urocanase

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MYDNSSTTAAMTIKLDAEFPPDPVFEPGIRRAPSRGFHLTPDQTKIALRNALRYLPPELHEKAVPEFLEELRTYGRIYAY
RWRPAGHIKGRPIDDYEGRCTEGKAFQVQIDNNLDFDVALYPYELVTYGETGSVCQN

Sequences:

>Translated_137_residues
MYDNSSTTAAMTIKLDAEFPPDPVFEPGIRRAPSRGFHLTPDQTKIALRNALRYLPPELHEKAVPEFLEELRTYGRIYAY
RWRPAGHIKGRPIDDYEGRCTEGKAFQVQIDNNLDFDVALYPYELVTYGETGSVCQN
>Mature_137_residues
MYDNSSTTAAMTIKLDAEFPPDPVFEPGIRRAPSRGFHLTPDQTKIALRNALRYLPPELHEKAVPEFLEELRTYGRIYAY
RWRPAGHIKGRPIDDYEGRCTEGKAFQVQIDNNLDFDVALYPYELVTYGETGSVCQN

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI21389467, Length=119, Percent_Identity=42.8571428571429, Blast_Score=95, Evalue=1e-20,
Organism=Homo sapiens, GI260306182, Length=112, Percent_Identity=44.6428571428571, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71997891, Length=109, Percent_Identity=44.0366972477064, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.49

Molecular weight: Translated: 15685; Mature: 15685

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDNSSTTAAMTIKLDAEFPPDPVFEPGIRRAPSRGFHLTPDQTKIALRNALRYLPPELH
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCHHHH
EKAVPEFLEELRTYGRIYAYRWRPAGHIKGRPIDDYEGRCTEGKAFQVQIDNNLDFDVAL
HHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
YPYELVTYGETGSVCQN
CCEEEEEECCCCCCCCC
>Mature Secondary Structure
MYDNSSTTAAMTIKLDAEFPPDPVFEPGIRRAPSRGFHLTPDQTKIALRNALRYLPPELH
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCHHHH
EKAVPEFLEELRTYGRIYAYRWRPAGHIKGRPIDDYEGRCTEGKAFQVQIDNNLDFDVAL
HHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
YPYELVTYGETGSVCQN
CCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate

Specific reaction: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA