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The map label for this gene is degP [H]

Identifier: 50843554

GI number: 50843554

Start: 2290050

End: 2291243

Strand: Direct

Name: degP [H]

Synonym: PPA2116

Alternate gene names: 50843554

Gene position: 2290050-2291243 (Clockwise)

Preceding gene: 50843552

Following gene: 50843555

Centisome position: 89.45

GC content: 62.73

Gene sequence:

>1194_bases
ATGGTGCACATCCTCGACATCACCCTCGCGGTGATCCTCATCCTCCGCGCCCTGCGCGGATGGACCCGAGGAGCAATTTC
TGGGATCGCCAGCCTCATCGGCTTGATTGGCGGAGTCTGGGTAGGGCTGTGGGCGTCGGGAGACATCGTGTCCCGGATCA
CCAACAACTCATCGTCCTGGCTTGCTACCGGACCACTACGCTTTGGCGTCGTCCTCGTCATCGTCGAAGTCATCCATGGC
CTCTGTAATGGGCTCGCCCGCCGCATATGCCACGCCTCTGAGACAGCAGGGTTAGGGGCCCTTGACCGGATTGGCGGCGC
ATTGCTGTCTGCGACCGCCACGGCCTTGGTAGTGGCGGTGGGGGCAACGGCGTTGGCCCCACTTCTGCCTCCCCAATGGA
CTCAGGCTATTGACGAATCAGCCGTCATCAACACCACCAACCGCGCAATTCCACCCCAAATCAATCACGAAACGGCACGG
CTTATCGGCCAGATGGCCGATACCTTCCCGAAGGTCTTTACCGGTCAGGACCCTCGTCTGCCCGGAGATGCCCCCGACGA
CTCCGCCGCCAATAGCCCTGGAGTACGACAAGCGGCGAGGTCCATCGTCAAAGTGAGATCACTGTCGCATCAATGTGACC
GGGCCTCGGAGGGCACCGGATGGGTCAGCTCACCGCACCGCGTCGTCACCAACGCCCATGTGGTCGCCGGATCTGACACA
GTGACGGTGCAGGTTGGAGGCCAAGGCGCCCGCCTGCGAGCGCGTGTCGTCGCCTACGACCCCGACCTCGACCTTGCCGT
GCTCGCTGTTCCTAAACTTAAGGCTCCTGCCCTAACAATGACCTCATCGGTAGACGCCGGGGACTCGACGGTCATCGCCG
GATTCCCGCTGGACGGACCGTACACAGTCAACGCTGCGCGAGTGCGCGGGGCAATAACGGCTCGTGGCGAGAACATTTAC
GGTGACGACGATGTCGTCCGCGAGATCCTGTCTTTGCGCGGCACCGTGCAACCGGGCAACTCAGGCGGTCCATTACTGAC
CACCGACGGAAAGGTAGCGGGCACGATCTTCGCCAGGTCCACCTCGCAACCGCAAGCCGGCTACGCCCTCACCAACCGAG
AAACCCGGCAGCTCATCAGGTCTGGTACGTATGGCTCCACCCCGGCATCGACCGGACGTTGCAGTGTCGCCTGA

Upstream 100 bases:

>100_bases
AAGTCGAATACGCTGTAGCTTGACGATATTGGCCCAATGTCGCCTCCTAGGCACGATTGAGACGCTGCTGATCCGTCCAC
CCACCCCTGATGGGAGAGCC

Downstream 100 bases:

>100_bases
ATCCGGAAAACCTTGGCCACCCAACCAACCAGGCGCCCCTTAGCGCTGCGCACATTTGCGGCTATCATCAACCCAAAACA
ACTCTGACAAGGTCTTTCGC

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MVHILDITLAVILILRALRGWTRGAISGIASLIGLIGGVWVGLWASGDIVSRITNNSSSWLATGPLRFGVVLVIVEVIHG
LCNGLARRICHASETAGLGALDRIGGALLSATATALVVAVGATALAPLLPPQWTQAIDESAVINTTNRAIPPQINHETAR
LIGQMADTFPKVFTGQDPRLPGDAPDDSAANSPGVRQAARSIVKVRSLSHQCDRASEGTGWVSSPHRVVTNAHVVAGSDT
VTVQVGGQGARLRARVVAYDPDLDLAVLAVPKLKAPALTMTSSVDAGDSTVIAGFPLDGPYTVNAARVRGAITARGENIY
GDDDVVREILSLRGTVQPGNSGGPLLTTDGKVAGTIFARSTSQPQAGYALTNRETRQLIRSGTYGSTPASTGRCSVA

Sequences:

>Translated_397_residues
MVHILDITLAVILILRALRGWTRGAISGIASLIGLIGGVWVGLWASGDIVSRITNNSSSWLATGPLRFGVVLVIVEVIHG
LCNGLARRICHASETAGLGALDRIGGALLSATATALVVAVGATALAPLLPPQWTQAIDESAVINTTNRAIPPQINHETAR
LIGQMADTFPKVFTGQDPRLPGDAPDDSAANSPGVRQAARSIVKVRSLSHQCDRASEGTGWVSSPHRVVTNAHVVAGSDT
VTVQVGGQGARLRARVVAYDPDLDLAVLAVPKLKAPALTMTSSVDAGDSTVIAGFPLDGPYTVNAARVRGAITARGENIY
GDDDVVREILSLRGTVQPGNSGGPLLTTDGKVAGTIFARSTSQPQAGYALTNRETRQLIRSGTYGSTPASTGRCSVA
>Mature_397_residues
MVHILDITLAVILILRALRGWTRGAISGIASLIGLIGGVWVGLWASGDIVSRITNNSSSWLATGPLRFGVVLVIVEVIHG
LCNGLARRICHASETAGLGALDRIGGALLSATATALVVAVGATALAPLLPPQWTQAIDESAVINTTNRAIPPQINHETAR
LIGQMADTFPKVFTGQDPRLPGDAPDDSAANSPGVRQAARSIVKVRSLSHQCDRASEGTGWVSSPHRVVTNAHVVAGSDT
VTVQVGGQGARLRARVVAYDPDLDLAVLAVPKLKAPALTMTSSVDAGDSTVIAGFPLDGPYTVNAARVRGAITARGENIY
GDDDVVREILSLRGTVQPGNSGGPLLTTDGKVAGTIFARSTSQPQAGYALTNRETRQLIRSGTYGSTPASTGRCSVA

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41099; Mature: 41099

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHILDITLAVILILRALRGWTRGAISGIASLIGLIGGVWVGLWASGDIVSRITNNSSSW
CEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCE
LATGPLRFGVVLVIVEVIHGLCNGLARRICHASETAGLGALDRIGGALLSATATALVVAV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATALAPLLPPQWTQAIDESAVINTTNRAIPPQINHETARLIGQMADTFPKVFTGQDPRL
HHHHHHHCCCCHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGDAPDDSAANSPGVRQAARSIVKVRSLSHQCDRASEGTGWVSSPHRVVTNAHVVAGSDT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCE
VTVQVGGQGARLRARVVAYDPDLDLAVLAVPKLKAPALTMTSSVDAGDSTVIAGFPLDGP
EEEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCEEEEECCCCCC
YTVNAARVRGAITARGENIYGDDDVVREILSLRGTVQPGNSGGPLLTTDGKVAGTIFARS
EEEEHHHHCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEEEC
TSQPQAGYALTNRETRQLIRSGTYGSTPASTGRCSVA
CCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVHILDITLAVILILRALRGWTRGAISGIASLIGLIGGVWVGLWASGDIVSRITNNSSSW
CEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCE
LATGPLRFGVVLVIVEVIHGLCNGLARRICHASETAGLGALDRIGGALLSATATALVVAV
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATALAPLLPPQWTQAIDESAVINTTNRAIPPQINHETARLIGQMADTFPKVFTGQDPRL
HHHHHHHCCCCHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGDAPDDSAANSPGVRQAARSIVKVRSLSHQCDRASEGTGWVSSPHRVVTNAHVVAGSDT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCE
VTVQVGGQGARLRARVVAYDPDLDLAVLAVPKLKAPALTMTSSVDAGDSTVIAGFPLDGP
EEEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCCEEEECCCCCCCCEEEEECCCCCC
YTVNAARVRGAITARGENIYGDDDVVREILSLRGTVQPGNSGGPLLTTDGKVAGTIFARS
EEEEHHHHCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEEEC
TSQPQAGYALTNRETRQLIRSGTYGSTPASTGRCSVA
CCCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]