Click here to switch to the map view.

The map label for this gene is 50843452

Identifier: 50843452

GI number: 50843452

Start: 2178218

End: 2178460

Strand: Reverse

Name: 50843452

Synonym: PPA2006

Alternate gene names: NA

Gene position: 2178460-2178218 (Counterclockwise)

Preceding gene: 50843453

Following gene: 50843451

Centisome position: 85.09

GC content: 61.32

Gene sequence:

>243_bases
ATGAGTGAGAACAATGAACTCGTCATCGAGACGCTGAACAAGCGACTCGCGGCGCTGGAAGCCGAGGTTTCCCGGCTCAA
GAAGACGAGCAAGGGCGTTCCTGAGGACGTGCTCGCCGCCATCTGCGCCGCCGTTTCGGCTTACCTGGGCAACGACGGAA
AGGTTCAGGCCGTCCGTTTCGCCCCGAGTGAGACCTGGGTCCGTCAGGGCCGCAGGGCTCAGCAGAACCATTCGATTCGT
TGA

Upstream 100 bases:

>100_bases
CCGCCGCTCTGGAGACCTACGCCACTAAGCGTCAGTCCCGTCCGGCCAAGAAGCACGGCGTCATGCCTTGCTGAGCGAAG
AAGGCTGATGGGAGGACAAG

Downstream 100 bases:

>100_bases
CCTGGAGAAACTGACATGAAGCTCAAGGTGACCGTCAATGACGTCGCATACGACGTTGACGTTGACGTTGATAAGACCGC
CAATGCGCCGATGGCGCCGA

Product: C-terminal fragment of methylmalonyl-CoA carboxyltransferase

Products: NA

Alternate protein names: Transcarboxylase 12S subunit [H]

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MSENNELVIETLNKRLAALEAEVSRLKKTSKGVPEDVLAAICAAVSAYLGNDGKVQAVRFAPSETWVRQGRRAQQNHSIR

Sequences:

>Translated_80_residues
MSENNELVIETLNKRLAALEAEVSRLKKTSKGVPEDVLAAICAAVSAYLGNDGKVQAVRFAPSETWVRQGRRAQQNHSIR
>Mature_79_residues
SENNELVIETLNKRLAALEAEVSRLKKTSKGVPEDVLAAICAAVSAYLGNDGKVQAVRFAPSETWVRQGRRAQQNHSIR

Specific function: The 12S subunit specifically catalyzes the transfer of the carboxyl group of methylmalonyl CoA to the biotin of the 1.3S subunit forming propanoyl-CoA and carboxylated 1.3S-biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 8792; Mature: 8661

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENNELVIETLNKRLAALEAEVSRLKKTSKGVPEDVLAAICAAVSAYLGNDGKVQAVRF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
APSETWVRQGRRAQQNHSIR
CCCHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
SENNELVIETLNKRLAALEAEVSRLKKTSKGVPEDVLAAICAAVSAYLGNDGKVQAVRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEE
APSETWVRQGRRAQQNHSIR
CCCHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366018 [H]