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The map label for this gene is nuoC [H]

Identifier: 50843384

GI number: 50843384

Start: 2095937

End: 2096761

Strand: Reverse

Name: nuoC [H]

Synonym: PPA1934

Alternate gene names: 50843384

Gene position: 2096761-2095937 (Counterclockwise)

Preceding gene: 50843385

Following gene: 50843383

Centisome position: 81.9

GC content: 62.79

Gene sequence:

>825_bases
ATGAGTGACAAGCCGACCCCGCGCGGCGCCGCAGGCGGCTCGGACTCCGGGGATCGCATCCCCGATGGCCGCAACTTCCT
TGATCCCAGCCATCCCGACCAGGTCCACACCCCCGCGAAGGGCCGTGAGTGGACCGATCGTCGCATCGATACCCGAAAGG
GTATGTGGGGAGCGACCTCCGGCCCCGGAGACACGTCTGGTTACGGCGGCATCGTTCGCACCGTCGAAATCTCTGGCAAC
TCTGAGCGCCCCTATGGCGGCTGGTTCGACGAGGTTGCGGATCGCATGGCGGAGCTCGTCCCCGACTTTTCTGACGGCCT
GACTGTGGTTGATCGTGGGGAGATCACCTTCTTCGTCCGTCCTGAGAAGCTCCTCGAACTCGTCAAGGTTCTTCGAGACG
ATGACGCCCTGCGGTTCGAAAGCTGTACATCGCTGACCTGCGTGCATTACCCGCACATGGCAGGACGCGAAATGCACGTT
GTCTACAACTTGTTGTCAATGACCCATAACCGTCGCATTCGCCTTGAGGTGGCGCTGGCCGATCCCGGTCAGGAGGACGT
TGCTCGTACCGGGCGCAGCGACGTCGATTCCCTGCCACACGTTCCCAGCGTCGTGTCGGTTTACCCGCACGCCGACTGGC
AGGAACGCGAGGCCTGGGACATGTTTGGGGTCATTTTTGATGGCCACCCGGCCTTGACTCGCATCCTCATGCCCGACGAT
TGGGTCGGCCATCCGCAGCGCAAGGACTACCCGCTTGGCGGTATCCCGATCGAGTACAAGGGTGCCGTCGTGCCACCGCC
GGACCAGCGCAGGAGCTACAACTGA

Upstream 100 bases:

>100_bases
AGCATTGGCCACTCATGGGCCACATGTCCGAGGTCGAGGCAGCCAAGGAGAAGAAGGCCCTCGACGCCAAGACCACTCTC
GAGCAGAAGGGGCTCATGCG

Downstream 100 bases:

>100_bases
TGAGCGAGAATCACGAGTACTTGTCCCAGGGCGGCGACTGGGCCCAGATCGTTGATGAGGCTGCCGAGCGAGGCGACGAG
ACCGTCGTCGTGAATTTCGG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSDKPTPRGAAGGSDSGDRIPDGRNFLDPSHPDQVHTPAKGREWTDRRIDTRKGMWGATSGPGDTSGYGGIVRTVEISGN
SERPYGGWFDEVADRMAELVPDFSDGLTVVDRGEITFFVRPEKLLELVKVLRDDDALRFESCTSLTCVHYPHMAGREMHV
VYNLLSMTHNRRIRLEVALADPGQEDVARTGRSDVDSLPHVPSVVSVYPHADWQEREAWDMFGVIFDGHPALTRILMPDD
WVGHPQRKDYPLGGIPIEYKGAVVPPPDQRRSYN

Sequences:

>Translated_274_residues
MSDKPTPRGAAGGSDSGDRIPDGRNFLDPSHPDQVHTPAKGREWTDRRIDTRKGMWGATSGPGDTSGYGGIVRTVEISGN
SERPYGGWFDEVADRMAELVPDFSDGLTVVDRGEITFFVRPEKLLELVKVLRDDDALRFESCTSLTCVHYPHMAGREMHV
VYNLLSMTHNRRIRLEVALADPGQEDVARTGRSDVDSLPHVPSVVSVYPHADWQEREAWDMFGVIFDGHPALTRILMPDD
WVGHPQRKDYPLGGIPIEYKGAVVPPPDQRRSYN
>Mature_273_residues
SDKPTPRGAAGGSDSGDRIPDGRNFLDPSHPDQVHTPAKGREWTDRRIDTRKGMWGATSGPGDTSGYGGIVRTVEISGNS
ERPYGGWFDEVADRMAELVPDFSDGLTVVDRGEITFFVRPEKLLELVKVLRDDDALRFESCTSLTCVHYPHMAGREMHVV
YNLLSMTHNRRIRLEVALADPGQEDVARTGRSDVDSLPHVPSVVSVYPHADWQEREAWDMFGVIFDGHPALTRILMPDDW
VGHPQRKDYPLGGIPIEYKGAVVPPPDQRRSYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=159, Percent_Identity=37.1069182389937, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI145693162, Length=103, Percent_Identity=44.6601941747573, Blast_Score=95, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=158, Percent_Identity=31.6455696202532, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32563621, Length=158, Percent_Identity=31.6455696202532, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656494, Length=159, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 30589; Mature: 30457

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKPTPRGAAGGSDSGDRIPDGRNFLDPSHPDQVHTPAKGREWTDRRIDTRKGMWGATS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
GPGDTSGYGGIVRTVEISGNSERPYGGWFDEVADRMAELVPDFSDGLTVVDRGEITFFVR
CCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEC
PEKLLELVKVLRDDDALRFESCTSLTCVHYPHMAGREMHVVYNLLSMTHNRRIRLEVALA
HHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
DPGQEDVARTGRSDVDSLPHVPSVVSVYPHADWQEREAWDMFGVIFDGHPALTRILMPDD
CCCHHHHHHCCCCHHHHCCCCCCCEEECCCCCCCHHHHHHEEEEEECCCHHHEEEECCCC
WVGHPQRKDYPLGGIPIEYKGAVVPPPDQRRSYN
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDKPTPRGAAGGSDSGDRIPDGRNFLDPSHPDQVHTPAKGREWTDRRIDTRKGMWGATS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
GPGDTSGYGGIVRTVEISGNSERPYGGWFDEVADRMAELVPDFSDGLTVVDRGEITFFVR
CCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEC
PEKLLELVKVLRDDDALRFESCTSLTCVHYPHMAGREMHVVYNLLSMTHNRRIRLEVALA
HHHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEC
DPGQEDVARTGRSDVDSLPHVPSVVSVYPHADWQEREAWDMFGVIFDGHPALTRILMPDD
CCCHHHHHHCCCCHHHHCCCCCCCEEECCCCCCCHHHHHHEEEEEECCCHHHEEEECCCC
WVGHPQRKDYPLGGIPIEYKGAVVPPPDQRRSYN
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA