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The map label for this gene is purN

Identifier: 50843208

GI number: 50843208

Start: 1909522

End: 1910145

Strand: Reverse

Name: purN

Synonym: PPA1748

Alternate gene names: 50843208

Gene position: 1910145-1909522 (Counterclockwise)

Preceding gene: 50843209

Following gene: 50843207

Centisome position: 74.61

GC content: 61.38

Gene sequence:

>624_bases
GTGGCCTTTCGCGTCGTCGTCCTCGTCTCAGGTACCGGAACCCTCTTGCAGTCCCTCATCGACAACCTGCCCGAGCAGGT
GAGCATCGTCGCCGTCGGTTCTGACCAGCCCGATGCTGTCGCCCTGCAACGAGCCCAGGCAGTCGGCATCCCGACCTTCG
CCGAGCCGCTACCGCGCAGCGATGCGCAGACGACTATGCGCGCGGCTTGGGATACTCGTCTGACTGACGCTGTCGCTCGT
TTCGATCCTGACTTGGTCGTCTGCGCCGGATTCATGAAGTTGCTCGGACAGACTTTCCTGGACCGGTTCGGTGGACGCAC
CATTAACTCCCACCCAGCCCTGTTGCCGTCTTTCCCAGGAATCCACGGCCCCCGCGATGCTTTGGAATACGGGGTCAAAA
TTACCGGGGCTACTGTCTTTATGGTTGACGCCGGAGTTGACACCGGCCGAATCCTCGCCCAACGGGCTGTGCCCGTCCTC
ACCGACGACACCGTCGAGTCCCTTCACGAACGCATCAAGGTGAAGGAACGCGAAATGCTTGTCACGGTGGTCACAGAACT
TGCCGGGGTGCGTCCCGGCATGGAAGAACTCGGCACCGAATCGTCTCGAAAGGATCCCCAGTGA

Upstream 100 bases:

>100_bases
GGGTTATGAGGCTGCCCAAGCAGCTATCGCTACCCTCACCGCGTTGTCCACTGCCCTTGCGTCTGGCCCATCGTAGACCC
AGAGGGCTTAAGGTGGGGTT

Downstream 100 bases:

>100_bases
GCGAACGTCAACCCATCCGTCGGGCCCTCGTCTCCGTCTACGACAAGTCTGGTCTTGACCAGTTGGCCAAGGCCCTTATT
GACGCGCAGGTCGAGGTGGT

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MAFRVVVLVSGTGTLLQSLIDNLPEQVSIVAVGSDQPDAVALQRAQAVGIPTFAEPLPRSDAQTTMRAAWDTRLTDAVAR
FDPDLVVCAGFMKLLGQTFLDRFGGRTINSHPALLPSFPGIHGPRDALEYGVKITGATVFMVDAGVDTGRILAQRAVPVL
TDDTVESLHERIKVKEREMLVTVVTELAGVRPGMEELGTESSRKDPQ

Sequences:

>Translated_207_residues
MAFRVVVLVSGTGTLLQSLIDNLPEQVSIVAVGSDQPDAVALQRAQAVGIPTFAEPLPRSDAQTTMRAAWDTRLTDAVAR
FDPDLVVCAGFMKLLGQTFLDRFGGRTINSHPALLPSFPGIHGPRDALEYGVKITGATVFMVDAGVDTGRILAQRAVPVL
TDDTVESLHERIKVKEREMLVTVVTELAGVRPGMEELGTESSRKDPQ
>Mature_206_residues
AFRVVVLVSGTGTLLQSLIDNLPEQVSIVAVGSDQPDAVALQRAQAVGIPTFAEPLPRSDAQTTMRAAWDTRLTDAVARF
DPDLVVCAGFMKLLGQTFLDRFGGRTINSHPALLPSFPGIHGPRDALEYGVKITGATVFMVDAGVDTGRILAQRAVPVLT
DDTVESLHERIKVKEREMLVTVVTELAGVRPGMEELGTESSRKDPQ

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=184, Percent_Identity=39.6739130434783, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI209869995, Length=184, Percent_Identity=39.6739130434783, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI209869993, Length=184, Percent_Identity=39.6739130434783, Blast_Score=123, Evalue=1e-28,
Organism=Escherichia coli, GI1788846, Length=196, Percent_Identity=35.2040816326531, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1787483, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567511, Length=189, Percent_Identity=39.1534391534392, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320616, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24582400, Length=179, Percent_Identity=42.4581005586592, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 22263; Mature: 22132

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFRVVVLVSGTGTLLQSLIDNLPEQVSIVAVGSDQPDAVALQRAQAVGIPTFAEPLPRS
CCEEEEEEECCCHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCCC
DAQTTMRAAWDTRLTDAVARFDPDLVVCAGFMKLLGQTFLDRFGGRTINSHPALLPSFPG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IHGPRDALEYGVKITGATVFMVDAGVDTGRILAQRAVPVLTDDTVESLHERIKVKEREML
CCCCHHHHHHCCEEECEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VTVVTELAGVRPGMEELGTESSRKDPQ
HHHHHHHHCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
AFRVVVLVSGTGTLLQSLIDNLPEQVSIVAVGSDQPDAVALQRAQAVGIPTFAEPLPRS
CEEEEEEECCCHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCCC
DAQTTMRAAWDTRLTDAVARFDPDLVVCAGFMKLLGQTFLDRFGGRTINSHPALLPSFPG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IHGPRDALEYGVKITGATVFMVDAGVDTGRILAQRAVPVLTDDTVESLHERIKVKEREML
CCCCHHHHHHCCEEECEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VTVVTELAGVRPGMEELGTESSRKDPQ
HHHHHHHHCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]