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The map label for this gene is fkbP [H]

Identifier: 50842866

GI number: 50842866

Start: 1504621

End: 1505745

Strand: Reverse

Name: fkbP [H]

Synonym: PPA1384

Alternate gene names: 50842866

Gene position: 1505745-1504621 (Counterclockwise)

Preceding gene: 50842867

Following gene: 50842864

Centisome position: 58.81

GC content: 57.24

Gene sequence:

>1125_bases
ATGAAGAACTGGGCCAGCTCCTCGACCTCGTCGAACTGTGAGTTCTCGCGCATGGCTGGAATTGTCCTCAAGCATCGCTC
GGGTAACCTCAAGCAGGTGAGTTCGAACAAGTATCGTCTGGTCAACGCCGCGGCACTCGCTGCCGTCCTGTGCGTGTCGT
CACTGGTCCTCGCTTCCTGTAACAAGTCGTCGTCGAGTCCGAAGCCTTCGGCGAGTGTCTCCAGCGTTTCGGCCCCCGCT
TCTGCCAGCGCCAAGGCCTCCTCTTCCCCAACGAAGAAGCCGACTATGGTCACTAACCTCGACCAGATCAAGGTGTCTGG
CGAGGACGGCAAGGCGCCAAAGGTTGAGGGAGCCTGGCCGCTAGCTATTGCTAAAACCGAGTCCAAAATCCTCAAGGAGG
GCACAGGCGAAAAGGTCGACAAGAACGCCACCCTCAAAGTGAATTATGTCGGTGTCAACGGACGTACTGGCAAGGAATTC
GACTCTTCCTATAAGCGTGGCACTACGGCTGACTTCCCATTGGCCCAGGTGGTTCCTGGATTCGCTAAGGGTCTTGTTGG
AAAGCATCAGGGCGACCGAGTACTCATCATGATGCCCGGCTCTGACGGCTATGACTCCCAAGGTGGTGCCCCGCAAGCTG
GCATCATGAAGGGTGACTCCCTTATTTTTGTCGTCGACATCGTTGCCATACCTTTGCCCAAGGCGACGGGTGAGACCGTC
AAACCGGCGGCTGGTCTGCCCACCGTCAAGGAGGTGCAGGGTGCTCCCGCGGTAACCATCGGCAAGGCCACCAAGCCGAA
TAAACTCGTCGTCCAGCCCCTCATCAAGGGTAAGGGAGCTGCGGTTACTGCTCATGACTCCATCGACGTCAAGTACCGCA
CTTATGCTTGGTCCTCTGGGGAGCTCATTGAGGACGGATACTCCGGTGAGCCTGTGACTGGATCCATGAACTCCGTTATT
CCTGGATGGAAGAAGGGATTGATTGGGCAGACCGTCGGTTCTCGGGTGATGCTCATCGTGCCGCCCGCTGACGCCTACCC
GAACGGCAGCACTAACCCGCCGGTAAAGAAGGGCGAGACCCTGATCTACGTTATCGACATCCTTTCGGCTCAAAAAGAAT
CCTGA

Upstream 100 bases:

>100_bases
ATGGATTCGGTCGCTCATCCAGTGCGTCGACTGTCTCGCACCGCGATCGGCCCGGTCCGATTGAAGCGGTTAGGGCGCGG
AGATATGCGTGAACTTACCC

Downstream 100 bases:

>100_bases
GTGGCGATGGCTTTGCGCGAGACATGTCGGCCGATATGTGTCTTAGGGTCGACGGGTCTCGCGCAGCACCGCCACATCGA
GAACCGCATCACTCCACCAC

Product: putative peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKNWASSSTSSNCEFSRMAGIVLKHRSGNLKQVSSNKYRLVNAAALAAVLCVSSLVLASCNKSSSSPKPSASVSSVSAPA
SASAKASSSPTKKPTMVTNLDQIKVSGEDGKAPKVEGAWPLAIAKTESKILKEGTGEKVDKNATLKVNYVGVNGRTGKEF
DSSYKRGTTADFPLAQVVPGFAKGLVGKHQGDRVLIMMPGSDGYDSQGGAPQAGIMKGDSLIFVVDIVAIPLPKATGETV
KPAAGLPTVKEVQGAPAVTIGKATKPNKLVVQPLIKGKGAAVTAHDSIDVKYRTYAWSSGELIEDGYSGEPVTGSMNSVI
PGWKKGLIGQTVGSRVMLIVPPADAYPNGSTNPPVKKGETLIYVIDILSAQKES

Sequences:

>Translated_374_residues
MKNWASSSTSSNCEFSRMAGIVLKHRSGNLKQVSSNKYRLVNAAALAAVLCVSSLVLASCNKSSSSPKPSASVSSVSAPA
SASAKASSSPTKKPTMVTNLDQIKVSGEDGKAPKVEGAWPLAIAKTESKILKEGTGEKVDKNATLKVNYVGVNGRTGKEF
DSSYKRGTTADFPLAQVVPGFAKGLVGKHQGDRVLIMMPGSDGYDSQGGAPQAGIMKGDSLIFVVDIVAIPLPKATGETV
KPAAGLPTVKEVQGAPAVTIGKATKPNKLVVQPLIKGKGAAVTAHDSIDVKYRTYAWSSGELIEDGYSGEPVTGSMNSVI
PGWKKGLIGQTVGSRVMLIVPPADAYPNGSTNPPVKKGETLIYVIDILSAQKES
>Mature_374_residues
MKNWASSSTSSNCEFSRMAGIVLKHRSGNLKQVSSNKYRLVNAAALAAVLCVSSLVLASCNKSSSSPKPSASVSSVSAPA
SASAKASSSPTKKPTMVTNLDQIKVSGEDGKAPKVEGAWPLAIAKTESKILKEGTGEKVDKNATLKVNYVGVNGRTGKEF
DSSYKRGTTADFPLAQVVPGFAKGLVGKHQGDRVLIMMPGSDGYDSQGGAPQAGIMKGDSLIFVVDIVAIPLPKATGETV
KPAAGLPTVKEVQGAPAVTIGKATKPNKLVVQPLIKGKGAAVTAHDSIDVKYRTYAWSSGELIEDGYSGEPVTGSMNSVI
PGWKKGLIGQTVGSRVMLIVPPADAYPNGSTNPPVKKGETLIYVIDILSAQKES

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 38784; Mature: 38784

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWASSSTSSNCEFSRMAGIVLKHRSGNLKQVSSNKYRLVNAAALAAVLCVSSLVLASC
CCCCCCCCCCCCCCHHHHEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHC
NKSSSSPKPSASVSSVSAPASASAKASSSPTKKPTMVTNLDQIKVSGEDGKAPKVEGAWP
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCE
LAIAKTESKILKEGTGEKVDKNATLKVNYVGVNGRTGKEFDSSYKRGTTADFPLAQVVPG
EEEECCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCH
FAKGLVGKHQGDRVLIMMPGSDGYDSQGGAPQAGIMKGDSLIFVVDIVAIPLPKATGETV
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCCCCCCCC
KPAAGLPTVKEVQGAPAVTIGKATKPNKLVVQPLIKGKGAAVTAHDSIDVKYRTYAWSSG
CCCCCCCCHHHHCCCCEEEECCCCCCCEEEEEHHHCCCCCEEEECCCEEEEEEEEEECCC
ELIEDGYSGEPVTGSMNSVIPGWKKGLIGQTVGSRVMLIVPPADAYPNGSTNPPVKKGET
CEECCCCCCCCCCCCHHHCCCCHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCE
LIYVIDILSAQKES
EEEEEEECCCCCCC
>Mature Secondary Structure
MKNWASSSTSSNCEFSRMAGIVLKHRSGNLKQVSSNKYRLVNAAALAAVLCVSSLVLASC
CCCCCCCCCCCCCCHHHHEEEEEEECCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHC
NKSSSSPKPSASVSSVSAPASASAKASSSPTKKPTMVTNLDQIKVSGEDGKAPKVEGAWP
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCE
LAIAKTESKILKEGTGEKVDKNATLKVNYVGVNGRTGKEFDSSYKRGTTADFPLAQVVPG
EEEECCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHCCH
FAKGLVGKHQGDRVLIMMPGSDGYDSQGGAPQAGIMKGDSLIFVVDIVAIPLPKATGETV
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCCCCCCCCC
KPAAGLPTVKEVQGAPAVTIGKATKPNKLVVQPLIKGKGAAVTAHDSIDVKYRTYAWSSG
CCCCCCCCHHHHCCCCEEEECCCCCCCEEEEEHHHCCCCCEEEECCCEEEEEEEEEECCC
ELIEDGYSGEPVTGSMNSVIPGWKKGLIGQTVGSRVMLIVPPADAYPNGSTNPPVKKGET
CEECCCCCCCCCCCCHHHCCCCHHHCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCE
LIYVIDILSAQKES
EEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1381710 [H]