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The map label for this gene is argD [H]

Identifier: 50842831

GI number: 50842831

Start: 1470717

End: 1471913

Strand: Reverse

Name: argD [H]

Synonym: PPA1347

Alternate gene names: 50842831

Gene position: 1471913-1470717 (Counterclockwise)

Preceding gene: 50842832

Following gene: 50842830

Centisome position: 57.49

GC content: 58.31

Gene sequence:

>1197_bases
ATGGCGGAGCAACAAACGAACGGCAATTGGCAAGAGCGCTACCACAATGCACTTCTCGGCGTGTTTGGCAATCCTCAGCT
GTGCCTAGACCACGGCCAGGGTTGCGTCGTTGTCGACAATGATGGCAAGGAATACCTGGACTTGCTGGCTGGAATTGCGG
TCAACGCCTTGGGATATGCCCATCCAGCGTGGGTCGAGGCTGTGAGCCATCAGTCAGAGACACTGGCTCATGTCTCGAAC
TTTTTTACCACGGGGCCCCAGCTGGATCTCGCAGAAAAACTCCTTGCACTGGCGAAAGCACCAAAGGGGTCGGCAGTGTT
TCTCTCGAACTCTGGTACTGAAGCCAATGAGGCGGCCATCAAGATCTGTTTGGCTCGCAAAAACGGACGTATCATCGCCC
TTGATCATGCTTTCCACGGTCGTAGTCTCGGCGCTCTTTCGTTGACCCACAAGATCGCTTACCGTCAACCGTTCGGTCCC
TCGGCTGTCGATGTCACCTTCATAGCTCCCGAAGACCCAGACGCATTAGCTAGTGAGCTAGACAGGGGCGATGTTTCCGG
GGTCTTTATGGAACCCATTCAGGGTGAGGCTGGGGTCGTCCCTTTGTCGGATGAATACCTACAGCAGGTACGCGAGCTGA
CGGCCTGCCACGATGTCCTCATGGTCGTCGACGAGGTGCAATGTGGCATGGGACGTACCGGTCGCTGGTTTGCGCACCAG
AGCGCCCACATCACCCCCGACGTGATGACTATGGCGAAAGCACTGGGAGGCGGCTTTCCTATCGGTGTGACGATGACGTT
CGGATCGGACGTGTCTGGGATCCTCGCAGCCGGGCAGCACGGGACTACCTTCGGCGGCAACCCGCTAGCTTGTGCTGCGG
CGTTAGCGGTCATTTCTACGATCGAATCCGATGATCTACTGACTCACGTCCGTCAGATCGGCACCTTGATGTCGACCGCG
CTGCGCCAAAGTCATCCGCGCATTACAGAGGTACGGGGTACCGGTGCTCTCCTTGGCGTCCAGTTCGATTCGGACATCGC
CGCCGATCTTGTCGCGGCTGCCCGCGATGCTGGGTTCATCGTCAACGCTGTTAACCCATCGACACTGAGGTTGGCCCCGC
CCTACATCCTCACGAAGGCGGAGGCCGAGTCCTTCATCGCTGCCCTTCCCCGTCTCATTGACGCGGTGCAGGCCTGA

Upstream 100 bases:

>100_bases
GTAGACGGACGCATTGAACACGCCCTTTTGCTGGAGATTTTCACTACCAGGGGCGTCGGAACAATGGCACGCAGCGACGA
CTATGTCTGAGAGGATGACG

Downstream 100 bases:

>100_bases
CGATCCTCCTTGATGCCGTGGGATGGGGTTTGAAGACGGTGTGAAGGACGGTAGGTAAGCTGAAAATCCCCGACAGAGGA
GTTCTTTGTGACCACCGAAC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAEQQTNGNWQERYHNALLGVFGNPQLCLDHGQGCVVVDNDGKEYLDLLAGIAVNALGYAHPAWVEAVSHQSETLAHVSN
FFTTGPQLDLAEKLLALAKAPKGSAVFLSNSGTEANEAAIKICLARKNGRIIALDHAFHGRSLGALSLTHKIAYRQPFGP
SAVDVTFIAPEDPDALASELDRGDVSGVFMEPIQGEAGVVPLSDEYLQQVRELTACHDVLMVVDEVQCGMGRTGRWFAHQ
SAHITPDVMTMAKALGGGFPIGVTMTFGSDVSGILAAGQHGTTFGGNPLACAAALAVISTIESDDLLTHVRQIGTLMSTA
LRQSHPRITEVRGTGALLGVQFDSDIAADLVAAARDAGFIVNAVNPSTLRLAPPYILTKAEAESFIAALPRLIDAVQA

Sequences:

>Translated_398_residues
MAEQQTNGNWQERYHNALLGVFGNPQLCLDHGQGCVVVDNDGKEYLDLLAGIAVNALGYAHPAWVEAVSHQSETLAHVSN
FFTTGPQLDLAEKLLALAKAPKGSAVFLSNSGTEANEAAIKICLARKNGRIIALDHAFHGRSLGALSLTHKIAYRQPFGP
SAVDVTFIAPEDPDALASELDRGDVSGVFMEPIQGEAGVVPLSDEYLQQVRELTACHDVLMVVDEVQCGMGRTGRWFAHQ
SAHITPDVMTMAKALGGGFPIGVTMTFGSDVSGILAAGQHGTTFGGNPLACAAALAVISTIESDDLLTHVRQIGTLMSTA
LRQSHPRITEVRGTGALLGVQFDSDIAADLVAAARDAGFIVNAVNPSTLRLAPPYILTKAEAESFIAALPRLIDAVQA
>Mature_397_residues
AEQQTNGNWQERYHNALLGVFGNPQLCLDHGQGCVVVDNDGKEYLDLLAGIAVNALGYAHPAWVEAVSHQSETLAHVSNF
FTTGPQLDLAEKLLALAKAPKGSAVFLSNSGTEANEAAIKICLARKNGRIIALDHAFHGRSLGALSLTHKIAYRQPFGPS
AVDVTFIAPEDPDALASELDRGDVSGVFMEPIQGEAGVVPLSDEYLQQVRELTACHDVLMVVDEVQCGMGRTGRWFAHQS
AHITPDVMTMAKALGGGFPIGVTMTFGSDVSGILAAGQHGTTFGGNPLACAAALAVISTIESDDLLTHVRQIGTLMSTAL
RQSHPRITEVRGTGALLGVQFDSDIAADLVAAARDAGFIVNAVNPSTLRLAPPYILTKAEAESFIAALPRLIDAVQA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=31.7708333333333, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=30.1369863013699, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.5548172757475, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=25.5369928400955, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=401, Percent_Identity=28.927680798005, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=25.78125, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=24.8210023866348, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI188536080, Length=420, Percent_Identity=25.952380952381, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38679950, Length=420, Percent_Identity=25.952380952381, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI38679946, Length=420, Percent_Identity=25.952380952381, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789759, Length=384, Percent_Identity=38.8020833333333, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788044, Length=386, Percent_Identity=38.860103626943, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI145693181, Length=381, Percent_Identity=36.4829396325459, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=32.5814536340852, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787560, Length=362, Percent_Identity=33.7016574585635, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786991, Length=395, Percent_Identity=28.3544303797468, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=353, Percent_Identity=27.7620396600567, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=370, Percent_Identity=30.5405405405405, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI32564660, Length=415, Percent_Identity=28.1927710843373, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=414, Percent_Identity=29.4685990338164, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=359, Percent_Identity=27.2980501392758, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17541228, Length=408, Percent_Identity=29.1666666666667, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=38.8059701492537, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6323470, Length=429, Percent_Identity=29.6037296037296, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324386, Length=323, Percent_Identity=28.4829721362229, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=435, Percent_Identity=27.1264367816092, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=31.331592689295, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=29.2740046838407, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=28.8056206088993, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21356575, Length=413, Percent_Identity=27.6029055690073, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=25.2336448598131, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=25.2336448598131, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=25.2336448598131, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41993; Mature: 41862

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQQTNGNWQERYHNALLGVFGNPQLCLDHGQGCVVVDNDGKEYLDLLAGIAVNALGYA
CCCCCCCCCHHHHHHHHHEEECCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCCC
HPAWVEAVSHQSETLAHVSNFFTTGPQLDLAEKLLALAKAPKGSAVFLSNSGTEANEAAI
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEE
KICLARKNGRIIALDHAFHGRSLGALSLTHKIAYRQPFGPSAVDVTFIAPEDPDALASEL
EEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHC
DRGDVSGVFMEPIQGEAGVVPLSDEYLQQVRELTACHDVLMVVDEVQCGMGRTGRWFAHQ
CCCCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
SAHITPDVMTMAKALGGGFPIGVTMTFGSDVSGILAAGQHGTTFGGNPLACAAALAVIST
CCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
IESDDLLTHVRQIGTLMSTALRQSHPRITEVRGTGALLGVQFDSDIAADLVAAARDAGFI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCHHHHHHHHHHCCCCEE
VNAVNPSTLRLAPPYILTKAEAESFIAALPRLIDAVQA
EECCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEQQTNGNWQERYHNALLGVFGNPQLCLDHGQGCVVVDNDGKEYLDLLAGIAVNALGYA
CCCCCCCCHHHHHHHHHEEECCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCCC
HPAWVEAVSHQSETLAHVSNFFTTGPQLDLAEKLLALAKAPKGSAVFLSNSGTEANEAAI
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEE
KICLARKNGRIIALDHAFHGRSLGALSLTHKIAYRQPFGPSAVDVTFIAPEDPDALASEL
EEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHC
DRGDVSGVFMEPIQGEAGVVPLSDEYLQQVRELTACHDVLMVVDEVQCGMGRTGRWFAHQ
CCCCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
SAHITPDVMTMAKALGGGFPIGVTMTFGSDVSGILAAGQHGTTFGGNPLACAAALAVIST
CCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
IESDDLLTHVRQIGTLMSTALRQSHPRITEVRGTGALLGVQFDSDIAADLVAAARDAGFI
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCHHHHHHHHHHCCCCEE
VNAVNPSTLRLAPPYILTKAEAESFIAALPRLIDAVQA
EECCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]