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The map label for this gene is argB

Identifier: 50842832

GI number: 50842832

Start: 1471924

End: 1472856

Strand: Reverse

Name: argB

Synonym: PPA1348

Alternate gene names: 50842832

Gene position: 1472856-1471924 (Counterclockwise)

Preceding gene: 50842833

Following gene: 50842831

Centisome position: 57.53

GC content: 57.02

Gene sequence:

>933_bases
ATGACCCTTGCTCTTGACATCCCCCTCAACGACACCCAGTTCTCGGCTCAGCGGAAATCTGAGGTCCTGGTAGAAGCGCT
GCCTTGGATCAGGCGGTTTCAGGGCCGCACTGTCGTCGTGAAATATGGCGGCAACGCGATGGTTGATCCCGGCCTGCAGC
AGGCCTTCGCCGACGACATTGTGTTTATGGCCTCTGTGGGGATTCGCCCTATTGTCGTCCACGGTGGTGGCCCTCAGATC
AATGCGATGCTTGCTGAATCTGCTACCCCAGTGGAGTTCCGTAATGGTTTGCGGGTGACATCTCCGGAGGTCATGGAGGT
TGTCCGGATGGTGCTCGTCGGGCAGGTGGGCCGTCAGCTCGTTAATCGAATCAACGCCTATGCGCCGCTAGCAGCTGGCA
TGTCAGGTGAGGACTCTGGACTTTTGTCGGCCCGGAAGTCGCGGGTAATTGTTGATGGCGAGCAAATAGACATGGGTTTG
GTGGGAGACATCGTTGACGTCAACATCGATCTCGTTATCTCTATGCTTGATCGCGGTCAGATTCCGGTTATTGCACCGGT
GAGTCCCGAGGTTGACGCGGCTGGTCGTCCCACCGGACAGGTTCTCAACGTCAATGCCGACACTGCCGCCACCGCTATTG
CTCAAGCACTACGTGCGGAAAAGCTCGTCATGCTGACAAACGTCGCTGGTATTTATGGCACCTGGCCTGACCCTCACACT
CTTATCTCTGAGGTCTCCGCGAGTGATTTGCGTGCCATGATTCCGCGTCTAGGTGAGGGTATGCGTCCGAAGGCGCAGGC
TCTGCTTGATGCCATTGACGGCGGGGTCTCGAGTGCTGCGATTGTAGACGGACGCATTGAACACGCCCTTTTGCTGGAGA
TTTTCACTACCAGGGGCGTCGGAACAATGGCACGCAGCGACGACTATGTCTGA

Upstream 100 bases:

>100_bases
TTCACATCGATATTGAGCTGCATGCGGGTGACGCCGAAGCTGCGGTATGGACCAATGATCTGACCCACCAATACGTCGAA
GAGAATAGCGCGTATACATC

Downstream 100 bases:

>100_bases
GAGGATGACGATGGCGGAGCAACAAACGAACGGCAATTGGCAAGAGCGCTACCACAATGCACTTCTCGGCGTGTTTGGCA
ATCCTCAGCTGTGCCTAGAC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDIVFMASVGIRPIVVHGGGPQI
NAMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQLVNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGL
VGDIVDVNIDLVISMLDRGQIPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHT
LISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGVGTMARSDDYV

Sequences:

>Translated_310_residues
MTLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDIVFMASVGIRPIVVHGGGPQI
NAMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQLVNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGL
VGDIVDVNIDLVISMLDRGQIPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHT
LISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGVGTMARSDDYV
>Mature_309_residues
TLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDIVFMASVGIRPIVVHGGGPQIN
AMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQLVNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGLV
GDIVDVNIDLVISMLDRGQIPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHTL
ISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGVGTMARSDDYV

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=299, Percent_Identity=27.0903010033445, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=276, Percent_Identity=28.6231884057971, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PROAC (Q6A814)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056059.1
- ProteinModelPortal:   Q6A814
- SMR:   Q6A814
- GeneID:   2931820
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1348
- NMPDR:   fig|267747.1.peg.1336
- HOGENOM:   HBG497643
- OMA:   DGEYEIN
- ProtClustDB:   PRK00942
- BioCyc:   PACN267747:PPA1348-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32913; Mature: 32782

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: BINDING 98-98 BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDI
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCHHHHHHHHH
VFMASVGIRPIVVHGGGPQINAMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQL
HHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGLVGDIVDVNIDLVISMLDRGQ
HHHHHHHCHHHCCCCCCCCCHHHHCCCEEEECCCEECCCEECCEECCHHHHHHHHHCCCC
IPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHT
CCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHH
LISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC
GTMARSDDYV
CCCCCCCCCC
>Mature Secondary Structure 
TLALDIPLNDTQFSAQRKSEVLVEALPWIRRFQGRTVVVKYGGNAMVDPGLQQAFADDI
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECCCHHHHHHHHH
VFMASVGIRPIVVHGGGPQINAMLAESATPVEFRNGLRVTSPEVMEVVRMVLVGQVGRQL
HHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VNRINAYAPLAAGMSGEDSGLLSARKSRVIVDGEQIDMGLVGDIVDVNIDLVISMLDRGQ
HHHHHHHCHHHCCCCCCCCCHHHHCCCEEEECCCEECCCEECCEECCHHHHHHHHHCCCC
IPVIAPVSPEVDAAGRPTGQVLNVNADTAATAIAQALRAEKLVMLTNVAGIYGTWPDPHT
CCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHH
LISEVSASDLRAMIPRLGEGMRPKAQALLDAIDGGVSSAAIVDGRIEHALLLEIFTTRGV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC
GTMARSDDYV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA