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The map label for this gene is ppiB [H]

Identifier: 50842578

GI number: 50842578

Start: 1191527

End: 1192303

Strand: Direct

Name: ppiB [H]

Synonym: PPA1100

Alternate gene names: 50842578

Gene position: 1191527-1192303 (Clockwise)

Preceding gene: 50842571

Following gene: 50842580

Centisome position: 46.54

GC content: 59.72

Gene sequence:

>777_bases
ATGAGGATGACGCGCCGAGCAACAACCGCAGTCGCCGTGGCAGGGCTGTCCTTGCTTGCCGGGTGCTCACAGACCAACGG
AACAGTGCCCGGGGTCAGCGACTCCCCTGATGCGTGGTGGACGAGCTTACCGTCTGCGACGAGTGGGTCTGCCAACTCCA
GGGCGGCTACGCACGCTGCCGGTACGGCATCAGCGACGACCACTCCAGCGCCCGCAGCGGCCAGCGGTCCGTGCGGTTAT
GCCGTCGCGGGCAAGGCTGCTCGCCCAGTTGATATGCCGCCTTCTGACAATATCGAAAAGACTGGTTCCACCACCGTCAC
TCTTACGATTAATGACGCTCCCGTGGTGCTTACTGTTGATCGGGCGATGGCCCCCTGTGCCGCCAACGCGTTTATCTCGT
TGGCCGAGCAGGGCTATTACAACGACACCTCATGTCACAAATTATCTACGGGAGATGCCAAGTACCTCCAGTGCGGTGAC
CCTTCCGGAACCGGGAATGGTGGTCCAGGATACTCCTATCCCGTTGAGAAGGAAGCCAAGGCCGGAGGATCAGTTGGCTC
CGGCACTCTTGCCTTGGTCGCCGATTCCCAGCATCGGCTGGGCTCGCAATTCGCCCTGGTTTATGGTGACTCCAAGCTGT
CGGATTCCTTCCTCGTCATTGGAAGTATCGATAAGGACGGTGCTGGGAGCATCTCTGACATCGCTCATAAGGGGCTCGCT
GACGATGGCCTTACTCCAAAGGTCGACACCAAGATTGGCTCGGTTGTGATGGGCTGA

Upstream 100 bases:

>100_bases
CCGTCGGGGCAGGTTGGTATAACCCCGTGAGTCTTCACTCTATTCCGTTGTGCTGATAGGTAGCCTGACCGCGTCGCCAA
TCGACCGAAGGACGGATTAC

Downstream 100 bases:

>100_bases
GCCTTAGCGAGGGGTGAGAGGCCCCTGGCACCGTGATAGGAAGGCCGCTAGCACTTGCACGAAGACTCCCGGCTGGTCTG
AATGCACCCAGTGGCCGGAA

Product: peptidyl-prolyl cis-trans isomerase B

Products: NA

Alternate protein names: PPIase B; Rotamase B [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRMTRRATTAVAVAGLSLLAGCSQTNGTVPGVSDSPDAWWTSLPSATSGSANSRAATHAAGTASATTTPAPAAASGPCGY
AVAGKAARPVDMPPSDNIEKTGSTTVTLTINDAPVVLTVDRAMAPCAANAFISLAEQGYYNDTSCHKLSTGDAKYLQCGD
PSGTGNGGPGYSYPVEKEAKAGGSVGSGTLALVADSQHRLGSQFALVYGDSKLSDSFLVIGSIDKDGAGSISDIAHKGLA
DDGLTPKVDTKIGSVVMG

Sequences:

>Translated_258_residues
MRMTRRATTAVAVAGLSLLAGCSQTNGTVPGVSDSPDAWWTSLPSATSGSANSRAATHAAGTASATTTPAPAAASGPCGY
AVAGKAARPVDMPPSDNIEKTGSTTVTLTINDAPVVLTVDRAMAPCAANAFISLAEQGYYNDTSCHKLSTGDAKYLQCGD
PSGTGNGGPGYSYPVEKEAKAGGSVGSGTLALVADSQHRLGSQFALVYGDSKLSDSFLVIGSIDKDGAGSISDIAHKGLA
DDGLTPKVDTKIGSVVMG
>Mature_258_residues
MRMTRRATTAVAVAGLSLLAGCSQTNGTVPGVSDSPDAWWTSLPSATSGSANSRAATHAAGTASATTTPAPAAASGPCGY
AVAGKAARPVDMPPSDNIEKTGSTTVTLTINDAPVVLTVDRAMAPCAANAFISLAEQGYYNDTSCHKLSTGDAKYLQCGD
PSGTGNGGPGYSYPVEKEAKAGGSVGSGTLALVADSQHRLGSQFALVYGDSKLSDSFLVIGSIDKDGAGSISDIAHKGLA
DDGLTPKVDTKIGSVVMG

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 25717; Mature: 25717

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTRRATTAVAVAGLSLLAGCSQTNGTVPGVSDSPDAWWTSLPSATSGSANSRAATHAA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHCC
GTASATTTPAPAAASGPCGYAVAGKAARPVDMPPSDNIEKTGSTTVTLTINDAPVVLTVD
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEC
RAMAPCAANAFISLAEQGYYNDTSCHKLSTGDAKYLQCGDPSGTGNGGPGYSYPVEKEAK
CCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
AGGSVGSGTLALVADSQHRLGSQFALVYGDSKLSDSFLVIGSIDKDGAGSISDIAHKGLA
CCCCCCCCEEEEEECCCHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHCCCC
DDGLTPKVDTKIGSVVMG
CCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MRMTRRATTAVAVAGLSLLAGCSQTNGTVPGVSDSPDAWWTSLPSATSGSANSRAATHAA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHCC
GTASATTTPAPAAASGPCGYAVAGKAARPVDMPPSDNIEKTGSTTVTLTINDAPVVLTVD
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEC
RAMAPCAANAFISLAEQGYYNDTSCHKLSTGDAKYLQCGDPSGTGNGGPGYSYPVEKEAK
CCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
AGGSVGSGTLALVADSQHRLGSQFALVYGDSKLSDSFLVIGSIDKDGAGSISDIAHKGLA
CCCCCCCCEEEEEECCCHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHCCCC
DDGLTPKVDTKIGSVVMG
CCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]