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The map label for this gene is mtnN [H]

Identifier: 50842571

GI number: 50842571

Start: 1185480

End: 1186181

Strand: Direct

Name: mtnN [H]

Synonym: PPA1093

Alternate gene names: 50842571

Gene position: 1185480-1186181 (Clockwise)

Preceding gene: 50842570

Following gene: 50842578

Centisome position: 46.3

GC content: 60.26

Gene sequence:

>702_bases
GTGCTTGGTCTGATGGGGGCGATGGAGGATGAGGTGCGCCTCATCCGAGCTGACCTCGACGACGTCGAAGAGCTTGATGG
TCCGTGCGAATTACTGCGCGGACGGTTAGACGGTACCCCAGTAGTGCTGGCTAAATGCGGTATCGGCAAGGTGAATGCTG
CGTTAGCTGCTTCAGCAATGGTTCAGGCTGGCGCAACACGCATCGTCTTCACCGGAGTCGCTGGGGCTGTCGCGCCCGGA
TTAGGAATCGGTGACGTCGTTGTCGGCAATAGGTTCCAGCAGCATGATGCTGACGACACCGCATTTGGTAACCCGATCGG
TACTGTTCCTGGGGAACCACCGTACTGGGAACCGGATCCCGTCCTTTTCGCCCTAGTGCTAGACGTATTGCGCGCGCTGG
AGGAGCCTCGTGGCCATCAAGTGGTGGCGGGGCCAATAGTCAGTGGAGACCAGTTCATCGCTCAGGCCGAGAAGGTCGCC
TGGCTACGCGCCACATTTGGGGCTAGCGCCGTCGAAATGGAAGGTGCGGCTCTAGCACAGGCAGCCAATCGTCTCGGTGT
GCCTTTCGCTGTGGTGCGGATTCTGTCCGACTCTGCCGACGGTGATGCGGTAGCGGATTTTCCAGCATTCCTTAACAACG
CGGCCCATCGTGGCCGCGACCTCGCTCACGCCTTAGCTCGGCAGCACAGGCTCACGGCTTGA

Upstream 100 bases:

>100_bases
GTGAGGCGGTCGTCACCCGTCGGGGTGCCGGGGACCCCTCACTTTTCGAATGAGGCCATAAGCCTATGGACATGGTTTGC
TGACGGAGGGTTGTAAGAGA

Downstream 100 bases:

>100_bases
CGAGGCTGTCAGGCTCGTACGAGCAGGGCCCCTGGGGCTACACGGGTCCTCATTGTCGTCACTGTGCCGATGGGGTCTCC
ATCAACTTCCGCCAGGATCG

Product: 5`-methylthioadenosine/S-adenosylhomocysteine nuclosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MLGLMGAMEDEVRLIRADLDDVEELDGPCELLRGRLDGTPVVLAKCGIGKVNAALAASAMVQAGATRIVFTGVAGAVAPG
LGIGDVVVGNRFQQHDADDTAFGNPIGTVPGEPPYWEPDPVLFALVLDVLRALEEPRGHQVVAGPIVSGDQFIAQAEKVA
WLRATFGASAVEMEGAALAQAANRLGVPFAVVRILSDSADGDAVADFPAFLNNAAHRGRDLAHALARQHRLTA

Sequences:

>Translated_233_residues
MLGLMGAMEDEVRLIRADLDDVEELDGPCELLRGRLDGTPVVLAKCGIGKVNAALAASAMVQAGATRIVFTGVAGAVAPG
LGIGDVVVGNRFQQHDADDTAFGNPIGTVPGEPPYWEPDPVLFALVLDVLRALEEPRGHQVVAGPIVSGDQFIAQAEKVA
WLRATFGASAVEMEGAALAQAANRLGVPFAVVRILSDSADGDAVADFPAFLNNAAHRGRDLAHALARQHRLTA
>Mature_233_residues
MLGLMGAMEDEVRLIRADLDDVEELDGPCELLRGRLDGTPVVLAKCGIGKVNAALAASAMVQAGATRIVFTGVAGAVAPG
LGIGDVVVGNRFQQHDADDTAFGNPIGTVPGEPPYWEPDPVLFALVLDVLRALEEPRGHQVVAGPIVSGDQFIAQAEKVA
WLRATFGASAVEMEGAALAQAANRLGVPFAVVRILSDSADGDAVADFPAFLNNAAHRGRDLAHALARQHRLTA

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=39.5652173913043, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24259; Mature: 24259

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLMGAMEDEVRLIRADLDDVEELDGPCELLRGRLDGTPVVLAKCGIGKVNAALAASAM
CCCCCCCCHHHHHHHHHCHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHH
VQAGATRIVFTGVAGAVAPGLGIGDVVVGNRFQQHDADDTAFGNPIGTVPGEPPYWEPDP
HHCCCCEEEEECCHHHHHCCCCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
VLFALVLDVLRALEEPRGHQVVAGPIVSGDQFIAQAEKVAWLRATFGASAVEMEGAALAQ
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AANRLGVPFAVVRILSDSADGDAVADFPAFLNNAAHRGRDLAHALARQHRLTA
HHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLGLMGAMEDEVRLIRADLDDVEELDGPCELLRGRLDGTPVVLAKCGIGKVNAALAASAM
CCCCCCCCHHHHHHHHHCHHHHHHCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHH
VQAGATRIVFTGVAGAVAPGLGIGDVVVGNRFQQHDADDTAFGNPIGTVPGEPPYWEPDP
HHCCCCEEEEECCHHHHHCCCCCCHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
VLFALVLDVLRALEEPRGHQVVAGPIVSGDQFIAQAEKVAWLRATFGASAVEMEGAALAQ
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AANRLGVPFAVVRILSDSADGDAVADFPAFLNNAAHRGRDLAHALARQHRLTA
HHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA