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The map label for this gene is pdxS

Identifier: 50842449

GI number: 50842449

Start: 1049873

End: 1050787

Strand: Direct

Name: pdxS

Synonym: PPA0965

Alternate gene names: 50842449

Gene position: 1049873-1050787 (Clockwise)

Preceding gene: 50842447

Following gene: 50842450

Centisome position: 41.01

GC content: 61.97

Gene sequence:

>915_bases
ATGGGGTCCATGAGTGAACACATCCCTGCAACGAATAGCACTGGAACGACACGAGTCAAGCGTGGACTGGCCGACATGCT
CAAGGGTGGCGTCATCATGGACGTCGTCACCCCCGAGCAGGCGAAGATCGCCGAGGATGCCGGAGCTTGTGCCGTTATGG
CCCTGGAAAGAGTCCCTGCCGATATCCGAGCTCAGGGTGGCGTGGCAAGGATGAGCGACCCCGACCTTATCGAGGGCATC
ATCGAGGCTGTCTCCATCCCTGTGATGGCCAAGGCCAGGATCGGCCACTTCGTCGAGGCTCAAGTGCTCGAGTCCCTCAG
GGTGGACTTTATCGATGAGTCGGAAGTGCTTAGCCCGGCTGACTACGCCAATCACATCGATAAGTGGGCCTTTGGCGTCC
CCTTCGTGTGTGGGGCGACGAACCTGGGTGAGGCTCTGCGCCGCATCACCGAGGGCGCTGCGATGATCCGATCTAAGGGA
GAGGCGGGCACCGGAGATGTTTCCGAGGCCGTCCGTCACCTGCGTACCATCCGTGCTGAAATGGCGCGGTTGAGCAGCAT
GTCTCCCGACGAGCTCTATGTTGCGGCCAAAGAGCTGCAGGCTCCTTACGACCTCGTTGCCGAGGTAGCTCGCACGGGAG
AGCTGCCGGTGGTGCTTTTTGTCGCTGGGGGAGTGGCCACTCCCGCCGATGCCGCCCTGGTTATGCAGATGGGGGCCCAG
GGCGTCTTCGTGGGTTCGGGCATCTTCAAGTCCGGTAACCCGGCCGCTCGGGCCGCGGCTATCGTCAAGGCAACGACCGC
CTACGATGATCCCGACACAATTGCCGAGGTTTCTCGTGGTTTGGGCGAGGCCATGGTCGGCATCAATGTCGCTGATGTAC
CAGCCCCGCACCGTCTGGCTGAGCGAGGTTGGTGA

Upstream 100 bases:

>100_bases
AGGTCGACGACGAGGTCTGGTCTCATGACGGTGGACCGAAAAGTGGTCTAACGAAAGTGGTCATATATGGATCTTGTCAT
GAACCACAATCGTGGATTTC

Downstream 100 bases:

>100_bases
GATGGCCCCGCTTGTCGGGGTGGTGGCCCTGCAGGGCGGGTTCGCCGAGCACATTGAGGTTCTCGAGTCGCTGGGGGCCA
ATACTCGTCGGGTTCGTCGG

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MGSMSEHIPATNSTGTTRVKRGLADMLKGGVIMDVVTPEQAKIAEDAGACAVMALERVPADIRAQGGVARMSDPDLIEGI
IEAVSIPVMAKARIGHFVEAQVLESLRVDFIDESEVLSPADYANHIDKWAFGVPFVCGATNLGEALRRITEGAAMIRSKG
EAGTGDVSEAVRHLRTIRAEMARLSSMSPDELYVAAKELQAPYDLVAEVARTGELPVVLFVAGGVATPADAALVMQMGAQ
GVFVGSGIFKSGNPAARAAAIVKATTAYDDPDTIAEVSRGLGEAMVGINVADVPAPHRLAERGW

Sequences:

>Translated_304_residues
MGSMSEHIPATNSTGTTRVKRGLADMLKGGVIMDVVTPEQAKIAEDAGACAVMALERVPADIRAQGGVARMSDPDLIEGI
IEAVSIPVMAKARIGHFVEAQVLESLRVDFIDESEVLSPADYANHIDKWAFGVPFVCGATNLGEALRRITEGAAMIRSKG
EAGTGDVSEAVRHLRTIRAEMARLSSMSPDELYVAAKELQAPYDLVAEVARTGELPVVLFVAGGVATPADAALVMQMGAQ
GVFVGSGIFKSGNPAARAAAIVKATTAYDDPDTIAEVSRGLGEAMVGINVADVPAPHRLAERGW
>Mature_303_residues
GSMSEHIPATNSTGTTRVKRGLADMLKGGVIMDVVTPEQAKIAEDAGACAVMALERVPADIRAQGGVARMSDPDLIEGII
EAVSIPVMAKARIGHFVEAQVLESLRVDFIDESEVLSPADYANHIDKWAFGVPFVCGATNLGEALRRITEGAAMIRSKGE
AGTGDVSEAVRHLRTIRAEMARLSSMSPDELYVAAKELQAPYDLVAEVARTGELPVVLFVAGGVATPADAALVMQMGAQG
VFVGSGIFKSGNPAARAAAIVKATTAYDDPDTIAEVSRGLGEAMVGINVADVPAPHRLAERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=291, Percent_Identity=62.5429553264605, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6321049, Length=294, Percent_Identity=64.2857142857143, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6323996, Length=294, Percent_Identity=63.9455782312925, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_PROAC (Q6A948)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055676.1
- ProteinModelPortal:   Q6A948
- SMR:   Q6A948
- GeneID:   2932789
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0965
- NMPDR:   fig|267747.1.peg.953
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   PACN267747:PPA0965-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31806; Mature: 31675

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSMSEHIPATNSTGTTRVKRGLADMLKGGVIMDVVTPEQAKIAEDAGACAVMALERVPA
CCCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCCH
DIRAQGGVARMSDPDLIEGIIEAVSIPVMAKARIGHFVEAQVLESLRVDFIDESEVLSPA
HHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DYANHIDKWAFGVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSEAVRHLRTIRAE
HHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MARLSSMSPDELYVAAKELQAPYDLVAEVARTGELPVVLFVAGGVATPADAALVMQMGAQ
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCC
GVFVGSGIFKSGNPAARAAAIVKATTAYDDPDTIAEVSRGLGEAMVGINVADVPAPHRLA
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHH
ERGW
HCCC
>Mature Secondary Structure 
GSMSEHIPATNSTGTTRVKRGLADMLKGGVIMDVVTPEQAKIAEDAGACAVMALERVPA
CCCHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCCH
DIRAQGGVARMSDPDLIEGIIEAVSIPVMAKARIGHFVEAQVLESLRVDFIDESEVLSPA
HHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DYANHIDKWAFGVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSEAVRHLRTIRAE
HHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MARLSSMSPDELYVAAKELQAPYDLVAEVARTGELPVVLFVAGGVATPADAALVMQMGAQ
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCC
GVFVGSGIFKSGNPAARAAAIVKATTAYDDPDTIAEVSRGLGEAMVGINVADVPAPHRLA
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHH
ERGW
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA