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The map label for this gene is ybeX [C]

Identifier: 50842422

GI number: 50842422

Start: 1018002

End: 1019300

Strand: Direct

Name: ybeX [C]

Synonym: PPA0938

Alternate gene names: 50842422

Gene position: 1018002-1019300 (Clockwise)

Preceding gene: 50842421

Following gene: 50842423

Centisome position: 39.76

GC content: 58.74

Gene sequence:

>1299_bases
GTGACACGGCAAGAATGGATCGTTCTGGCGATCGCCTTCATCTTCACAGTGTTGGCAAGCCTCAATGTGGCCATGGAGAC
GGCCCTTCAACACATGTCTCACTCCAAGGCCGAGGAGCTTGCTGCCGACGGTAAAACTGCGCACCAACGAGTACTTGACA
TGGTCGCCGATCCCGCCCCCTTCATCAACACCGCGATGCTAGTGAGGGTTATTTCCGAGGTGACGGCGACGGCACTTGTC
GCGCTCCTTATTTTCGGCCACTTCGACCTGCCCTGGCAGCAGGTGCTCGTCGTCGTGGCCATCATGGTGCTTGTTGACTT
CCTGGCATGGGGAGTGGCTGCGCGCACCTTGGGGCGTCAGCATGACACCGCTATCTGCACCTTCTGGTCTCGTCCTTGGG
GAGTACTTGCCCACGTCCTTGGCCCCATCGCGGCCTTGCTTATCCTCATCGGCAACGCTCTGACCCCCGGAAAGGGATAT
GCCGAAGGCCCCTTTACCTCTGAGGCTGAACTACGCGAGATGGTCGACTACGCCGAGGCTTCCGACCTCATTGAGGCCGG
CGAGCGGGAGATGATCCACTCAGTCTTCGAGCTAGGTGACACCCTTACGAAGGAGGTCATGGTCCCGCGTACCGACGTGG
TCTATATTCCTCGGACCAAAAATCTGCGTCAGGCGATGTCTTTGGCTCTGCGATCTGGGTTTTCCCGAATTCCGGTCGTT
GGCGAAGGCTTTGACGACATCCGTGGCGTCGTCTATCTCAAGGATCTCTCCCAGCGGGTACTCGACAATCCTGACGGTTA
CGCCACCGAAAGCGTCGAATCGATCATGCGGCCTGCCGTGCTCTGCCCAGACTCTAAGCCCGTCGACCAGGTGCTGCGCG
AGATGCAGCGAGACCGTAACCATCTCGTCATCGTCGTAGACGAGTTTGGCGGCACGGCTGGCCTAGTGACGATCGAGGAC
ATCGTCGAGGAGATCGTTGGCGAGATTGTTGACGAGTATGACGCCGAGCCCACCCTCACGGAAGAGATCGAAGACGGCGT
CTTTCGAATATCCTCGCGTTTGCCGGTCGATGATCTGGGCGAACTGTTCGATCTTAAGGTCGACGATGACGACGTCGAGA
CGGTTGGTGGCCTCATGGCCAAGGAACTGTCTGTAGTACCCATCCCGGGATCTGTCATCATCTGGGAGGGGTTAGAGATC
ACCGCCGAGAAGGCGACCGGTCGCCGTCACCAGGTGGACACCTGCCTGGTAAAGCGGGCCCCCGAAGAAACCCCCGATCA
GGAGTATGACGATGAGTGA

Upstream 100 bases:

>100_bases
GCCACGACCATGCTGAACCCGGAGAGAAGCGCGTCATGTTTAGACTCAACGACGAGATCATCGCGGCATGGGATGACCAT
CGAGAACAGACAGGTCAGCG

Downstream 100 bases:

>100_bases
CGACGAGATGCCTTCGTTGGCCGATCTCATGGATGGCGATGACGAGGATATTTCCGACGTTGACTATGTGACCGCCAGGG
TAGCTGAATCTACCCGAGCC

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTRQEWIVLAIAFIFTVLASLNVAMETALQHMSHSKAEELAADGKTAHQRVLDMVADPAPFINTAMLVRVISEVTATALV
ALLIFGHFDLPWQQVLVVVAIMVLVDFLAWGVAARTLGRQHDTAICTFWSRPWGVLAHVLGPIAALLILIGNALTPGKGY
AEGPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNLRQAMSLALRSGFSRIPVV
GEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLCPDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIED
IVEEIVGEIVDEYDAEPTLTEEIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEI
TAEKATGRRHQVDTCLVKRAPEETPDQEYDDE

Sequences:

>Translated_432_residues
MTRQEWIVLAIAFIFTVLASLNVAMETALQHMSHSKAEELAADGKTAHQRVLDMVADPAPFINTAMLVRVISEVTATALV
ALLIFGHFDLPWQQVLVVVAIMVLVDFLAWGVAARTLGRQHDTAICTFWSRPWGVLAHVLGPIAALLILIGNALTPGKGY
AEGPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNLRQAMSLALRSGFSRIPVV
GEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLCPDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIED
IVEEIVGEIVDEYDAEPTLTEEIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEI
TAEKATGRRHQVDTCLVKRAPEETPDQEYDDE
>Mature_431_residues
TRQEWIVLAIAFIFTVLASLNVAMETALQHMSHSKAEELAADGKTAHQRVLDMVADPAPFINTAMLVRVISEVTATALVA
LLIFGHFDLPWQQVLVVVAIMVLVDFLAWGVAARTLGRQHDTAICTFWSRPWGVLAHVLGPIAALLILIGNALTPGKGYA
EGPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNLRQAMSLALRSGFSRIPVVG
EGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLCPDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIEDI
VEEIVGEIVDEYDAEPTLTEEIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEIT
AEKATGRRHQVDTCLVKRAPEETPDQEYDDE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=26.0526315789474, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1786879, Length=270, Percent_Identity=32.2222222222222, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI145693175, Length=377, Percent_Identity=23.8726790450928, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87082033, Length=222, Percent_Identity=27.9279279279279, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790664, Length=442, Percent_Identity=21.0407239819005, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47616; Mature: 47485

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQEWIVLAIAFIFTVLASLNVAMETALQHMSHSKAEELAADGKTAHQRVLDMVADPAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
FINTAMLVRVISEVTATALVALLIFGHFDLPWQQVLVVVAIMVLVDFLAWGVAARTLGRQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HDTAICTFWSRPWGVLAHVLGPIAALLILIGNALTPGKGYAEGPFTSEAELREMVDYAEA
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNLRQAMSLALRSGFSRIPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCC
GEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLCPDSKPVDQVLREMQRDRN
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCC
HLVIVVDEFGGTAGLVTIEDIVEEIVGEIVDEYDAEPTLTEEIEDGVFRISSRLPVDDLG
CEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
ELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEITAEKATGRRHQVDTCLVKRA
HHHCCCCCCCHHHHHHHHHHHCCEEEECCCCEEEECCCEEEHHHHCCCHHHHHHHHHHCC
PEETPDQEYDDE
CCCCCCCCCCCC
>Mature Secondary Structure 
TRQEWIVLAIAFIFTVLASLNVAMETALQHMSHSKAEELAADGKTAHQRVLDMVADPAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
FINTAMLVRVISEVTATALVALLIFGHFDLPWQQVLVVVAIMVLVDFLAWGVAARTLGRQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HDTAICTFWSRPWGVLAHVLGPIAALLILIGNALTPGKGYAEGPFTSEAELREMVDYAEA
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
SDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNLRQAMSLALRSGFSRIPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCC
GEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLCPDSKPVDQVLREMQRDRN
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHCCCC
HLVIVVDEFGGTAGLVTIEDIVEEIVGEIVDEYDAEPTLTEEIEDGVFRISSRLPVDDLG
CEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHH
ELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEITAEKATGRRHQVDTCLVKRA
HHHCCCCCCCHHHHHHHHHHHCCEEEECCCCEEEECCCEEEHHHHCCCHHHHHHHHHHCC
PEETPDQEYDDE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]