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The map label for this gene is era

Identifier: 50842423

GI number: 50842423

Start: 1019293

End: 1020315

Strand: Direct

Name: era

Synonym: PPA0939

Alternate gene names: 50842423

Gene position: 1019293-1020315 (Clockwise)

Preceding gene: 50842422

Following gene: 161621797

Centisome position: 39.81

GC content: 58.75

Gene sequence:

>1023_bases
ATGAGTGACGACGAGATGCCTTCGTTGGCCGATCTCATGGATGGCGATGACGAGGATATTTCCGACGTTGACTATGTGAC
CGCCAGGGTAGCTGAATCTACCCGAGCCGGATTCCACTCCGGGTTCGTCTGCTTCGTCGGGCGCCCAAATGCCGGCAAGT
CGACTCTCACCAACGCCCTGGTTGGTTCCAAGATCGCCATTGCCTCTTCGAAGCCTCAGACCACCCGTCACGTCATCCGT
GGCGTAGTCACTGACGAGAAATCTCAGATCGTCGTCATCGACACCCCGGGACTCCATAAGCCACGCACCCTACTGGGTCA
GCGGCTCAACGACCTCGTTTTCGACACTTGGACCCAGGTCGACGTTATCGGGGTGTGTTTGCCTTCCAACCAGCGAATTG
GGCCAGGTGACACCTATCTTGTATCGCAAATCGCCGAACTTCCTCGTCGCCCCACGCTTGTCGCCCTGGCAACGAAGTCC
GACCTCGTGTCCAAGGCGCGGATGGCTGAGCATCTGGCCACCATTGACAAGCTGCAAGGAGAGGTCGGCATCGAGTTCGT
TGAAATCGTCCCGTGCTCTGCGGTCTCCGGCGAGCAGGTCGACGAGGTCCGCGACGTCATTGCTTCCCTGCTGCCTGAAG
GGCCGGCCTACTACCCAGATGGTGAGGTGACTGACGAACCGACCGAAACCCTTGTCGCCGAGCTGATCCGCGAGGCGGCG
CTTGAAGGTGTGCGCGAGGAGCTTCCCCACTCTCTGGCTGTGGAGATTGTGGAGATGGGGCCTCGAGAAGGTCAGCCGGA
GGATCGTCCCCTACTGGACGTCTACGCATCCCTCATAGTGGAACGTGATTCCCAGAAGGGCATCATGATCGGTCATCATG
GTTCCCATATCAAGCAGGTTCGTACCCACGCCAGGCGACAGATCGCGGCCCTGTTGGGAACGCCAATCCACTTAGACCTT
CAGGTCAAGGTGTTGCCGAACTGGCAGTCCGACCCGAAATACCTCAATCGATTGGGGTTTTGA

Upstream 100 bases:

>100_bases
TTAGAGATCACCGCCGAGAAGGCGACCGGTCGCCGTCACCAGGTGGACACCTGCCTGGTAAAGCGGGCCCCCGAAGAAAC
CCCCGATCAGGAGTATGACG

Downstream 100 bases:

>100_bases
AATATTGGGTCGGTGGGAAGTGATGGTCTCACAGTGCTGCGGCCGTCACCTCTCCACCGACGACTGTTAAGTCGCTGGTG
ATGCCTGCCAATGCATTACC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSDDEMPSLADLMDGDDEDISDVDYVTARVAESTRAGFHSGFVCFVGRPNAGKSTLTNALVGSKIAIASSKPQTTRHVIR
GVVTDEKSQIVVIDTPGLHKPRTLLGQRLNDLVFDTWTQVDVIGVCLPSNQRIGPGDTYLVSQIAELPRRPTLVALATKS
DLVSKARMAEHLATIDKLQGEVGIEFVEIVPCSAVSGEQVDEVRDVIASLLPEGPAYYPDGEVTDEPTETLVAELIREAA
LEGVREELPHSLAVEIVEMGPREGQPEDRPLLDVYASLIVERDSQKGIMIGHHGSHIKQVRTHARRQIAALLGTPIHLDL
QVKVLPNWQSDPKYLNRLGF

Sequences:

>Translated_340_residues
MSDDEMPSLADLMDGDDEDISDVDYVTARVAESTRAGFHSGFVCFVGRPNAGKSTLTNALVGSKIAIASSKPQTTRHVIR
GVVTDEKSQIVVIDTPGLHKPRTLLGQRLNDLVFDTWTQVDVIGVCLPSNQRIGPGDTYLVSQIAELPRRPTLVALATKS
DLVSKARMAEHLATIDKLQGEVGIEFVEIVPCSAVSGEQVDEVRDVIASLLPEGPAYYPDGEVTDEPTETLVAELIREAA
LEGVREELPHSLAVEIVEMGPREGQPEDRPLLDVYASLIVERDSQKGIMIGHHGSHIKQVRTHARRQIAALLGTPIHLDL
QVKVLPNWQSDPKYLNRLGF
>Mature_339_residues
SDDEMPSLADLMDGDDEDISDVDYVTARVAESTRAGFHSGFVCFVGRPNAGKSTLTNALVGSKIAIASSKPQTTRHVIRG
VVTDEKSQIVVIDTPGLHKPRTLLGQRLNDLVFDTWTQVDVIGVCLPSNQRIGPGDTYLVSQIAELPRRPTLVALATKSD
LVSKARMAEHLATIDKLQGEVGIEFVEIVPCSAVSGEQVDEVRDVIASLLPEGPAYYPDGEVTDEPTETLVAELIREAAL
EGVREELPHSLAVEIVEMGPREGQPEDRPLLDVYASLIVERDSQKGIMIGHHGSHIKQVRTHARRQIAALLGTPIHLDLQ
VKVLPNWQSDPKYLNRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=303, Percent_Identity=33.003300330033, Blast_Score=174, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37112; Mature: 36980

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDEMPSLADLMDGDDEDISDVDYVTARVAESTRAGFHSGFVCFVGRPNAGKSTLTNAL
CCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
VGSKIAIASSKPQTTRHVIRGVVTDEKSQIVVIDTPGLHKPRTLLGQRLNDLVFDTWTQV
HCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCE
DVIGVCLPSNQRIGPGDTYLVSQIAELPRRPTLVALATKSDLVSKARMAEHLATIDKLQG
EEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
EVGIEFVEIVPCSAVSGEQVDEVRDVIASLLPEGPAYYPDGEVTDEPTETLVAELIREAA
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LEGVREELPHSLAVEIVEMGPREGQPEDRPLLDVYASLIVERDSQKGIMIGHHGSHIKQV
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
RTHARRQIAALLGTPIHLDLQVKVLPNWQSDPKYLNRLGF
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SDDEMPSLADLMDGDDEDISDVDYVTARVAESTRAGFHSGFVCFVGRPNAGKSTLTNAL
CCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
VGSKIAIASSKPQTTRHVIRGVVTDEKSQIVVIDTPGLHKPRTLLGQRLNDLVFDTWTQV
HCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCE
DVIGVCLPSNQRIGPGDTYLVSQIAELPRRPTLVALATKSDLVSKARMAEHLATIDKLQG
EEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
EVGIEFVEIVPCSAVSGEQVDEVRDVIASLLPEGPAYYPDGEVTDEPTETLVAELIREAA
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LEGVREELPHSLAVEIVEMGPREGQPEDRPLLDVYASLIVERDSQKGIMIGHHGSHIKQV
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
RTHARRQIAALLGTPIHLDLQVKVLPNWQSDPKYLNRLGF
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA