Click here to switch to the map view.

The map label for this gene is menC [H]

Identifier: 50842386

GI number: 50842386

Start: 983302

End: 984309

Strand: Direct

Name: menC [H]

Synonym: PPA0902

Alternate gene names: 50842386

Gene position: 983302-984309 (Clockwise)

Preceding gene: 50842385

Following gene: 50842387

Centisome position: 38.41

GC content: 63.0

Gene sequence:

>1008_bases
GTGAAGGGTCTGAAGGCGTACCGATTAGACGTTCCGCCCATGCTGGCCGATCGTGGTATTGATCGGATGCTCGCATTCGC
CGTGCCTCTGACAGTGAGGTTCCGTGGCATTAAGGTGCGGGAGGGAACTCTGCTCCACGGTCCAGAAGGTTGGGGAGAGT
GGTCGCCGTTTTGGGACTACGACCCGGTTGAGTCAGCGTCGTGGTTGCGCGCGGGAATCGAGGGTGCTACCCGGCGCCTA
CCCGTGGCGCGACGAGATCGGGTGCCGATAAATGTCACGATTCCCGTCGTCGACGCGGATCGTGCCGGGAGGATGGCTGC
CGAGTCGGCCTGCCTGACGGCCAAGGTCAAGGTTGCTGACCCTCGTAGCGATCTGCGCGAGGATTGCCGACGGGTCGCCG
CAGTGCGCGAAGCCATGCCAGACGGACACATTCGGGTGGACGCCAACACTGCCTGGGATGTTGATGCAGCGGTCCGTGCG
ATTACCGAGCTTGACGCCGCAGCCGAAGGGCTGGAATATGTCGAGCAGCCCTGCGCAAGCGTGGCGGAGCTGGCCCAGGT
CAGACGCAAGGTCAACGTGCCGGTGGCAGCTGACGAGTCAGTACGTAGAGCTGAGGATCCACTCGCGGTGGCACGTGCCG
GTGCTGCCGATCTCCTCATCGTTAAGGCACAACCGTTGGGTGGAGTTGCCCGAGCCCTTGAGGTCATCGATGCTACCGGG
TTACCAGCCGTCGTCTCCTCGGCCCTGGACACCAGTATCGGGATCGGGTTGGCTACTTATCTAGCGGCGGCCCTGCCCAG
CCTTGACCACGCCTGCGGGCTGGGGACAATTCGTCTTTTTCAGGGTGATGTCAGCGCCTCGCCACTCCTTCCGGTTGACG
GTTACCTGAGACCGCGGCGCGGGGAGGTTGACGTCGAGGTTGAGGAGTCGGATACGGATCTGTGTCCGAGGTGGTCACAG
CGTTTGGCTCTCACCGTGGCCGCCCTTGTTGAGCGAGAACGGAGTTGA

Upstream 100 bases:

>100_bases
AGAAGGCTGGTAAGAAGCGCATGAAGGTCGTCGGCTCGGTGGAAGTGCCTCAGGAGGCCTTTGTAGCTGCCTTGCGTACC
GGAGAGTCCACGGAGAAAAA

Downstream 100 bases:

>100_bases
GGTGAACCCCTCTACAGCAGTCGCCCGACGTCTGGTGAATGCTCTCGTTGAGGCCGGGGTCGAACACGTCGTGTATTGCC
CCGGATCCCGGGATGCCCCT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKGLKAYRLDVPPMLADRGIDRMLAFAVPLTVRFRGIKVREGTLLHGPEGWGEWSPFWDYDPVESASWLRAGIEGATRRL
PVARRDRVPINVTIPVVDADRAGRMAAESACLTAKVKVADPRSDLREDCRRVAAVREAMPDGHIRVDANTAWDVDAAVRA
ITELDAAAEGLEYVEQPCASVAELAQVRRKVNVPVAADESVRRAEDPLAVARAGAADLLIVKAQPLGGVARALEVIDATG
LPAVVSSALDTSIGIGLATYLAAALPSLDHACGLGTIRLFQGDVSASPLLPVDGYLRPRRGEVDVEVEESDTDLCPRWSQ
RLALTVAALVERERS

Sequences:

>Translated_335_residues
MKGLKAYRLDVPPMLADRGIDRMLAFAVPLTVRFRGIKVREGTLLHGPEGWGEWSPFWDYDPVESASWLRAGIEGATRRL
PVARRDRVPINVTIPVVDADRAGRMAAESACLTAKVKVADPRSDLREDCRRVAAVREAMPDGHIRVDANTAWDVDAAVRA
ITELDAAAEGLEYVEQPCASVAELAQVRRKVNVPVAADESVRRAEDPLAVARAGAADLLIVKAQPLGGVARALEVIDATG
LPAVVSSALDTSIGIGLATYLAAALPSLDHACGLGTIRLFQGDVSASPLLPVDGYLRPRRGEVDVEVEESDTDLCPRWSQ
RLALTVAALVERERS
>Mature_335_residues
MKGLKAYRLDVPPMLADRGIDRMLAFAVPLTVRFRGIKVREGTLLHGPEGWGEWSPFWDYDPVESASWLRAGIEGATRRL
PVARRDRVPINVTIPVVDADRAGRMAAESACLTAKVKVADPRSDLREDCRRVAAVREAMPDGHIRVDANTAWDVDAAVRA
ITELDAAAEGLEYVEQPCASVAELAQVRRKVNVPVAADESVRRAEDPLAVARAGAADLLIVKAQPLGGVARALEVIDATG
LPAVVSSALDTSIGIGLATYLAAALPSLDHACGLGTIRLFQGDVSASPLLPVDGYLRPRRGEVDVEVEESDTDLCPRWSQ
RLALTVAALVERERS

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36047; Mature: 36047

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLKAYRLDVPPMLADRGIDRMLAFAVPLTVRFRGIKVREGTLLHGPEGWGEWSPFWDY
CCCCCEEECCCCHHHHHCCHHHHHHHHCCEEEEEEEEEEECCEEEECCCCCCCCCCCCCC
DPVESASWLRAGIEGATRRLPVARRDRVPINVTIPVVDADRAGRMAAESACLTAKVKVAD
CCCCHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEEEEECCCCCCHHHHCHHEEEEEEECC
PRSDLREDCRRVAAVREAMPDGHIRVDANTAWDVDAAVRAITELDAAAEGLEYVEQPCAS
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAELAQVRRKVNVPVAADESVRRAEDPLAVARAGAADLLIVKAQPLGGVARALEVIDATG
HHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCC
LPAVVSSALDTSIGIGLATYLAAALPSLDHACGLGTIRLFQGDVSASPLLPVDGYLRPRR
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GEVDVEVEESDTDLCPRWSQRLALTVAALVERERS
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGLKAYRLDVPPMLADRGIDRMLAFAVPLTVRFRGIKVREGTLLHGPEGWGEWSPFWDY
CCCCCEEECCCCHHHHHCCHHHHHHHHCCEEEEEEEEEEECCEEEECCCCCCCCCCCCCC
DPVESASWLRAGIEGATRRLPVARRDRVPINVTIPVVDADRAGRMAAESACLTAKVKVAD
CCCCHHHHHHHHHHHHHHCCCCHHCCCCCEEEEEEEEECCCCCCHHHHCHHEEEEEEECC
PRSDLREDCRRVAAVREAMPDGHIRVDANTAWDVDAAVRAITELDAAAEGLEYVEQPCAS
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAELAQVRRKVNVPVAADESVRRAEDPLAVARAGAADLLIVKAQPLGGVARALEVIDATG
HHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCC
LPAVVSSALDTSIGIGLATYLAAALPSLDHACGLGTIRLFQGDVSASPLLPVDGYLRPRR
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GEVDVEVEESDTDLCPRWSQRLALTVAALVERERS
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]