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The map label for this gene is obgE

Identifier: 50842319

GI number: 50842319

Start: 913800

End: 915317

Strand: Direct

Name: obgE

Synonym: PPA0833

Alternate gene names: 50842319

Gene position: 913800-915317 (Clockwise)

Preceding gene: 50842318

Following gene: 50842320

Centisome position: 35.69

GC content: 62.12

Gene sequence:

>1518_bases
ATGGCCATCCCGTCCTTCGTGGACCGCGCGACGCTGACCGCCGTGGCGGGCAAGGGAGGACATGGCTGCGCCTCTGTCAA
GCGTGAGAAGTTCAAGCCGTTGGGGGGCCCCGACGGTGGCAACGGCGGCCATGGCGGGTCTGTAATCTTGCGCGTTGATC
CTCAAGTGACGACTCTTGTGGACTATCACTGGCAGTCCACCCGTAAGGCGACGAATGGCGAGTCCGGACGCGGTGATAAC
CAGGCTGGGGCCAATGGATCCGACATGATCTTGGCCGTCCCAGAGGGCACGGTCGTCTCTGACGCTGACACGGGCGAGCT
GCTAGGAGACCTCGTTGGGGTGGGGGCTGAACTCGTCGTTGCGGCTGGTGGTCGCGGTGGCCTCGGTAACGCAGCTCTTG
CGAACTCGGCTCGCAAGGCTCCCGGTTTTGCCCTGCTCGGTGAGGCCGGGGAGGAACGCAAGATCCTGCTCGAGCTCAAG
GTGGTCGCCGACATCGGCTTGGTGGGATTTCCTTCGGCGGGAAAGTCCAGCCTCATCGCGGCGATCTCGAGGGCTAAGCC
GAAGATTGCTGACTACCCATTCACCACCCTGGTGCCGAACTTAGGTGTGGTCGTCGCGGGGGAGACAACATATACCGTTG
CCGACGTGCCCGGCCTCATTCCAGGGGCGTCTGTGGGAAAGGGGCTGGGATTCGATTTTTTGCGCCACATTGAGCGGTGC
CGAGCCATCGTCCACGTCATTGACTGCGCCACCTACGAGCCTGGCCGCGACCCGGTCAGTGATCTCGACGTTATTGAAGG
GGAGCTTATTGCCCACGGTGGGCTTGAGGATCGTCCGCGCCTGGTGGTGCTCAACAAGGTTGACGTTCCTGATGCCGCTG
ATCTAGCCGATATCATCTTCGATGACGTCGCCGAGCGTGGCTGGCCGGTATCTCGAGTCTCGACGAAATCGGGGGAAGGG
CTTAATTCGCTCAAATTCGCGATGGCCGAGTTGGTCGAGAAGGCCCGCGACAACGAGCCTGAGCCCGAGCCGGAGCGCAT
CGTCATTCGACCCGAGCCCAAGAATGAGCGCCAGGCTTTCTCCATCAAACGTCAGGGTGACGGCGAAGGCGGGTTCCTGT
GGCGCGTGACTGGCGACAAACCGACTCGCTGGGTTGCCCAGACTGACTTCAACAATCCAGAGGCCGTCGGATACTTGTCG
GATCGCCTGAATCGTTTGGGTGTCGAGGAGGAATTGTTGGCTATGGGCGCCATCGCTGGTGACGCTGTCGCTGTCGGTGG
TGAGGACGCCGTCATTTTCGACTTTGCCCCGCAGATTGAGTCGGGCGCTGAGCTGCTGTCTCGCCGTGGCGAGGACCAGC
GCTTGAAGTCCGAGCGTCCTTCGGCTACTCGTCGTCGGGAGATGGACCGCGAATATCATCGTGCTCGAGAGGAGTATGGT
CAGGTCGGTCGTGACCTGCGCGGAGAGTCGTGGCGCGCCCGTGTTGCCGAAGAGGAGTGGTTCGAGGGCCGTGACTGA

Upstream 100 bases:

>100_bases
GCTCGAGACGTATCACGGGGGCCGGGTGACGCGTCCTAGCGTCTAAACTGGTTATCTGTCCTGGGTCGGAAGGCCCGATT
CCATTTTCTGAGGAGAGAAC

Downstream 100 bases:

>100_bases
TCAGCGCGGAGCCATATGCGGGGCCGCCACCCTGGTGGTCAAGGTCGGATCTTCCTCTTTGACTCTTCCTGGTGGCGGGA
TTGACGTTCGTCGTGTTGAC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MAIPSFVDRATLTAVAGKGGHGCASVKREKFKPLGGPDGGNGGHGGSVILRVDPQVTTLVDYHWQSTRKATNGESGRGDN
QAGANGSDMILAVPEGTVVSDADTGELLGDLVGVGAELVVAAGGRGGLGNAALANSARKAPGFALLGEAGEERKILLELK
VVADIGLVGFPSAGKSSLIAAISRAKPKIADYPFTTLVPNLGVVVAGETTYTVADVPGLIPGASVGKGLGFDFLRHIERC
RAIVHVIDCATYEPGRDPVSDLDVIEGELIAHGGLEDRPRLVVLNKVDVPDAADLADIIFDDVAERGWPVSRVSTKSGEG
LNSLKFAMAELVEKARDNEPEPEPERIVIRPEPKNERQAFSIKRQGDGEGGFLWRVTGDKPTRWVAQTDFNNPEAVGYLS
DRLNRLGVEEELLAMGAIAGDAVAVGGEDAVIFDFAPQIESGAELLSRRGEDQRLKSERPSATRRREMDREYHRAREEYG
QVGRDLRGESWRARVAEEEWFEGRD

Sequences:

>Translated_505_residues
MAIPSFVDRATLTAVAGKGGHGCASVKREKFKPLGGPDGGNGGHGGSVILRVDPQVTTLVDYHWQSTRKATNGESGRGDN
QAGANGSDMILAVPEGTVVSDADTGELLGDLVGVGAELVVAAGGRGGLGNAALANSARKAPGFALLGEAGEERKILLELK
VVADIGLVGFPSAGKSSLIAAISRAKPKIADYPFTTLVPNLGVVVAGETTYTVADVPGLIPGASVGKGLGFDFLRHIERC
RAIVHVIDCATYEPGRDPVSDLDVIEGELIAHGGLEDRPRLVVLNKVDVPDAADLADIIFDDVAERGWPVSRVSTKSGEG
LNSLKFAMAELVEKARDNEPEPEPERIVIRPEPKNERQAFSIKRQGDGEGGFLWRVTGDKPTRWVAQTDFNNPEAVGYLS
DRLNRLGVEEELLAMGAIAGDAVAVGGEDAVIFDFAPQIESGAELLSRRGEDQRLKSERPSATRRREMDREYHRAREEYG
QVGRDLRGESWRARVAEEEWFEGRD
>Mature_504_residues
AIPSFVDRATLTAVAGKGGHGCASVKREKFKPLGGPDGGNGGHGGSVILRVDPQVTTLVDYHWQSTRKATNGESGRGDNQ
AGANGSDMILAVPEGTVVSDADTGELLGDLVGVGAELVVAAGGRGGLGNAALANSARKAPGFALLGEAGEERKILLELKV
VADIGLVGFPSAGKSSLIAAISRAKPKIADYPFTTLVPNLGVVVAGETTYTVADVPGLIPGASVGKGLGFDFLRHIERCR
AIVHVIDCATYEPGRDPVSDLDVIEGELIAHGGLEDRPRLVVLNKVDVPDAADLADIIFDDVAERGWPVSRVSTKSGEGL
NSLKFAMAELVEKARDNEPEPEPERIVIRPEPKNERQAFSIKRQGDGEGGFLWRVTGDKPTRWVAQTDFNNPEAVGYLSD
RLNRLGVEEELLAMGAIAGDAVAVGGEDAVIFDFAPQIESGAELLSRRGEDQRLKSERPSATRRREMDREYHRAREEYGQ
VGRDLRGESWRARVAEEEWFEGRD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=41.0714285714286, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI111955139, Length=219, Percent_Identity=40.6392694063927, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI111955063, Length=187, Percent_Identity=37.9679144385027, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1789574, Length=349, Percent_Identity=42.6934097421203, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1787454, Length=127, Percent_Identity=36.2204724409449, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=287, Percent_Identity=43.5540069686411, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=28.2051282051282, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=130, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=41.9753086419753, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6319499, Length=151, Percent_Identity=34.4370860927152, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20129375, Length=339, Percent_Identity=38.3480825958702, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24585318, Length=226, Percent_Identity=38.0530973451327, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PROAC (Q6A9H8)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055546.1
- HSSP:   P20964
- ProteinModelPortal:   Q6A9H8
- SMR:   Q6A9H8
- GeneID:   2932515
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0833
- NMPDR:   fig|267747.1.peg.823
- HOGENOM:   HBG716038
- OMA:   IVHVLDC
- ProtClustDB:   PRK12296
- BioCyc:   PACN267747:PPA0833-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 53868; Mature: 53737

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPSFVDRATLTAVAGKGGHGCASVKREKFKPLGGPDGGNGGHGGSVILRVDPQVTTLV
CCCCHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
DYHWQSTRKATNGESGRGDNQAGANGSDMILAVPEGTVVSDADTGELLGDLVGVGAELVV
EHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHCCCCEEEE
AAGGRGGLGNAALANSARKAPGFALLGEAGEERKILLELKVVADIGLVGFPSAGKSSLIA
EECCCCCCCCHHHHCCCCCCCCEEEECCCCCCCEEEEEEEEEHHCCEEECCCCCHHHHHH
AISRAKPKIADYPFTTLVPNLGVVVAGETTYTVADVPGLIPGASVGKGLGFDFLRHIERC
HHHHCCCCCCCCCHHHHCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
RAIVHVIDCATYEPGRDPVSDLDVIEGELIAHGGLEDRPRLVVLNKVDVPDAADLADIIF
HHHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHH
DDVAERGWPVSRVSTKSGEGLNSLKFAMAELVEKARDNEPEPEPERIVIRPEPKNERQAF
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEE
SIKRQGDGEGGFLWRVTGDKPTRWVAQTDFNNPEAVGYLSDRLNRLGVEEELLAMGAIAG
EEEECCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
DAVAVGGEDAVIFDFAPQIESGAELLSRRGEDQRLKSERPSATRRREMDREYHRAREEYG
CEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QVGRDLRGESWRARVAEEEWFEGRD
HHHHCCCCCCHHHHCCHHHHCCCCC
>Mature Secondary Structure 
AIPSFVDRATLTAVAGKGGHGCASVKREKFKPLGGPDGGNGGHGGSVILRVDPQVTTLV
CCCHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEE
DYHWQSTRKATNGESGRGDNQAGANGSDMILAVPEGTVVSDADTGELLGDLVGVGAELVV
EHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHCCCCEEEE
AAGGRGGLGNAALANSARKAPGFALLGEAGEERKILLELKVVADIGLVGFPSAGKSSLIA
EECCCCCCCCHHHHCCCCCCCCEEEECCCCCCCEEEEEEEEEHHCCEEECCCCCHHHHHH
AISRAKPKIADYPFTTLVPNLGVVVAGETTYTVADVPGLIPGASVGKGLGFDFLRHIERC
HHHHCCCCCCCCCHHHHCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
RAIVHVIDCATYEPGRDPVSDLDVIEGELIAHGGLEDRPRLVVLNKVDVPDAADLADIIF
HHHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHH
DDVAERGWPVSRVSTKSGEGLNSLKFAMAELVEKARDNEPEPEPERIVIRPEPKNERQAF
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEE
SIKRQGDGEGGFLWRVTGDKPTRWVAQTDFNNPEAVGYLSDRLNRLGVEEELLAMGAIAG
EEEECCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
DAVAVGGEDAVIFDFAPQIESGAELLSRRGEDQRLKSERPSATRRREMDREYHRAREEYG
CEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QVGRDLRGESWRARVAEEEWFEGRD
HHHHCCCCCCHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA