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The map label for this gene is ftsW [C]

Identifier: 50842244

GI number: 50842244

Start: 832607

End: 833929

Strand: Direct

Name: ftsW [C]

Synonym: PPA0757

Alternate gene names: 50842244

Gene position: 832607-833929 (Clockwise)

Preceding gene: 50842243

Following gene: 50842245

Centisome position: 32.52

GC content: 59.11

Gene sequence:

>1323_bases
ATGCTGCTCGACACGTTGACGGGCCAGATGCCGATGGCTGAGAAATCGGTAGATTCACGGGTCCGCCGTACCACCCGACG
CCGGACTCCCGGCAGCTGGTTGAGGCATTTACTGCGACTTGACGGTGGTGACGGTTCCTCACGCCGATTGCTGGCTCAGC
CGTTTCTGGATTACTACGTCATCCTGGCTACTACCGTGCTGCTGTGCGGTATTGGCGCGTTGATGGGATTGTCATCCTCG
TCGGTGTACTCCCAGTCCCTGGGTCACGGGCCTTATCACTTTGCGATTCGTCAGATCCTGTTCCTGGTAGTGGGCGCTAT
CGCGGCAGCCGTGGTGTCGCGGCTCTCGGAGACACATCTGAGGCAACTTGGTGGGTTCGCCTATGCCGTCGTGTGTCTCA
TGCTCGTTTTGGTGCTGACCTTTTTGGGTTCAGACGCTGGAAAGGGAAATCAGTCATGGCTGTCTCTCGGACCGGTTAGT
TTGCAGCCCTCAGAGTTCGCAAAATTCGCCCTGGTGCTCCTTGGGGCGAGTTACATGTCTTCACGACGTGGCGAGATGGC
GACTCCGAAGGGCGTGGGGGGTTACCTTGGTCTATATGGGGTCGTCGGTCTGCTTGTTGTAGCTCAGGGAGACCTCGGCA
CAACGATGATTATTGGCCTTATCATGTTGGCCCAGATGTGGAACTTTGGAGTGCCCAAGCGTTATTTGGGTGCCCTCATT
GGCCTCGGTCTCTTGGCGGTGCTGCTGCTCACTGCCATCACCCCCTATCGCGCCGAGCGCGTGTTGTCGTTCCTGCACCC
AGACAATGGCGCCAGCACCTCCCAGCAGCCTCTTTCGGCGATTTATGCGCTGGCGACCGGTGGCTGGTGGGGTGTTGGTA
TCGGTGCCTCCCGACAGAAATGGGGCGGCCTTTATGATGGCGCTCAGAACGACTTCGTCTTTGCCGTTCTTGGTGAGGAA
ATGGGCCTGCTGGGTACCCTGGGTGTCATCCTGCTGTTTACCTTGCTGATATGGGCTGGCGTGCGCACAGCGATGCGGCA
GGATTCGTTGTTTCGTCGTTCAGCCGCGTCGACGGCCACCGCGTGGATTGCAGCTCAGGCCCTCATCAACATGTCTGTAT
CGCTGAACCTCTTGCCGGTCGTGGGCGTCCCGCTTCCGTTCATTTCTATCGGTGGTTCTGCACTAGTGTCGGCGCTGTTA
GCAGTGGGGCTTTTGTTGGCATGTGCCCGCACCGAGCCTGATGCCCGGCGAAGTACTGCTGCCTCGCAACGCACTGAGCC
GGCCCGAGTAACGAGCGTCGTCGATGGTGGCAACCGTGGCTGA

Upstream 100 bases:

>100_bases
GCCAAGATGGCTCGTCCTGGGGATACCGTCTTGATGGCACCTGGCTGTGCCAGCTTGGATATCTGGCCCGGCTATGCCGC
ACGCGGTGAGGACTTTGCCA

Downstream 100 bases:

>100_bases
TCTGAACCTCATTTGCCGTCTTTCTTCCCCAGAGGAGTACTCATGGTAAACGTTGTCTTGGCTGGCGGAGGAACGGCTGG
CCATACATCGCCGTTGATCG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MLLDTLTGQMPMAEKSVDSRVRRTTRRRTPGSWLRHLLRLDGGDGSSRRLLAQPFLDYYVILATTVLLCGIGALMGLSSS
SVYSQSLGHGPYHFAIRQILFLVVGAIAAAVVSRLSETHLRQLGGFAYAVVCLMLVLVLTFLGSDAGKGNQSWLSLGPVS
LQPSEFAKFALVLLGASYMSSRRGEMATPKGVGGYLGLYGVVGLLVVAQGDLGTTMIIGLIMLAQMWNFGVPKRYLGALI
GLGLLAVLLLTAITPYRAERVLSFLHPDNGASTSQQPLSAIYALATGGWWGVGIGASRQKWGGLYDGAQNDFVFAVLGEE
MGLLGTLGVILLFTLLIWAGVRTAMRQDSLFRRSAASTATAWIAAQALINMSVSLNLLPVVGVPLPFISIGGSALVSALL
AVGLLLACARTEPDARRSTAASQRTEPARVTSVVDGGNRG

Sequences:

>Translated_440_residues
MLLDTLTGQMPMAEKSVDSRVRRTTRRRTPGSWLRHLLRLDGGDGSSRRLLAQPFLDYYVILATTVLLCGIGALMGLSSS
SVYSQSLGHGPYHFAIRQILFLVVGAIAAAVVSRLSETHLRQLGGFAYAVVCLMLVLVLTFLGSDAGKGNQSWLSLGPVS
LQPSEFAKFALVLLGASYMSSRRGEMATPKGVGGYLGLYGVVGLLVVAQGDLGTTMIIGLIMLAQMWNFGVPKRYLGALI
GLGLLAVLLLTAITPYRAERVLSFLHPDNGASTSQQPLSAIYALATGGWWGVGIGASRQKWGGLYDGAQNDFVFAVLGEE
MGLLGTLGVILLFTLLIWAGVRTAMRQDSLFRRSAASTATAWIAAQALINMSVSLNLLPVVGVPLPFISIGGSALVSALL
AVGLLLACARTEPDARRSTAASQRTEPARVTSVVDGGNRG
>Mature_440_residues
MLLDTLTGQMPMAEKSVDSRVRRTTRRRTPGSWLRHLLRLDGGDGSSRRLLAQPFLDYYVILATTVLLCGIGALMGLSSS
SVYSQSLGHGPYHFAIRQILFLVVGAIAAAVVSRLSETHLRQLGGFAYAVVCLMLVLVLTFLGSDAGKGNQSWLSLGPVS
LQPSEFAKFALVLLGASYMSSRRGEMATPKGVGGYLGLYGVVGLLVVAQGDLGTTMIIGLIMLAQMWNFGVPKRYLGALI
GLGLLAVLLLTAITPYRAERVLSFLHPDNGASTSQQPLSAIYALATGGWWGVGIGASRQKWGGLYDGAQNDFVFAVLGEE
MGLLGTLGVILLFTLLIWAGVRTAMRQDSLFRRSAASTATAWIAAQALINMSVSLNLLPVVGVPLPFISIGGSALVSALL
AVGLLLACARTEPDARRSTAASQRTEPARVTSVVDGGNRG

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=31.8681318681319, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786853, Length=322, Percent_Identity=31.055900621118, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46553; Mature: 46553

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDTLTGQMPMAEKSVDSRVRRTTRRRTPGSWLRHLLRLDGGDGSSRRLLAQPFLDYYV
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ILATTVLLCGIGALMGLSSSSVYSQSLGHGPYHFAIRQILFLVVGAIAAAVVSRLSETHL
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLGGFAYAVVCLMLVLVLTFLGSDAGKGNQSWLSLGPVSLQPSEFAKFALVLLGASYMS
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
SRRGEMATPKGVGGYLGLYGVVGLLVVAQGDLGTTMIIGLIMLAQMWNFGVPKRYLGALI
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GLGLLAVLLLTAITPYRAERVLSFLHPDNGASTSQQPLSAIYALATGGWWGVGIGASRQK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCHHH
WGGLYDGAQNDFVFAVLGEEMGLLGTLGVILLFTLLIWAGVRTAMRQDSLFRRSAASTAT
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWIAAQALINMSVSLNLLPVVGVPLPFISIGGSALVSALLAVGLLLACARTEPDARRSTA
HHHHHHHHHHHHHHEEEEEHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ASQRTEPARVTSVVDGGNRG
HHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]