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The map label for this gene is murG

Identifier: 50842245

GI number: 50842245

Start: 833972

End: 835090

Strand: Direct

Name: murG

Synonym: PPA0758

Alternate gene names: 50842245

Gene position: 833972-835090 (Clockwise)

Preceding gene: 50842244

Following gene: 50842246

Centisome position: 32.57

GC content: 61.57

Gene sequence:

>1119_bases
ATGGTAAACGTTGTCTTGGCTGGCGGAGGAACGGCTGGCCATACATCGCCGTTGATCGCGACCGCGATGGCGCTGCAGGA
ACGTGGGGCGACGGTCTCGTGTATTGGTACGCCAAGGGGACTCGAGGGACGAGTTATCCCGGAAGCGGGGCTGCAACTTG
ACATGATTCCGCCGGTGCCGTTGCCCCGTACCGTTAATGCTGACCTATTCAAGGTTCCTGCTCGGCTAGCCGGGGCGGTG
CGTAAGGCTGGCGAGGTGCTTCAGCGTCGCCAGACCGACGTCGTCGTCGGGTTTGGTGGCTACGTGTCGTTGCCTGCGTA
TTTAGCGGCCAGGCGAGCCAAGATCCCGGTCGTCATCCACGAGCAGAATGCTGTGCCGGGGTTGGCGAACAAGATTGCCG
CACGCTTTGCCGTCTTCGTCGGTACGGCTTTCCCCGACACGCCCTTGCCCAAAGCGCGGTTTGTTGGCATGCCGTTGCGT
TCACAGATCACCGATTTGGCTGACGCTAGTGGGCAAGCCCGAGCTGAGCGTTGTGCCCGTGCTCGTGCTGACCTTGGTCT
TGACATCAACCGTCCAACTTTGTTGGTGTCGGGGGGCTCTCAGGGGGCGGTGGCCATTAATGAGGCGGTTGTTGCTGCGC
GGACACGTCTACTTGCAGACGGTGTGCAGATTCTTCACGTGCTCGGGCCGAAGAACATCCGGGGGGCTACGAGGATTACC
GACGAGTTGACCGGAGCGTCATGGTTGCCCATGGGATACGTTGACGACATGGCGAGTGCTTATGCGGCTGCCGACCTCAT
GGTGGCGCGTTCTGGCGCTGGAACAGTGGTGGAAACAGCGACCGTCGGTTTGCCGACTATCTATGTGCCGTTGCCGCACG
GTAATGGCGAGCAGGCGCGCAATGCCACCTCGGCGGTCGACGCCGGAGCTGGCGTTGTCGTCGCTAATGCTGATCTGGAC
GTTGAGCGCCTCCTTGCGGAGACTGCCCGCATCCATGATGCTGATGTTCTTGCCCAGATGTCAGCGGCAGGACGGGGACT
CATGCCCGCTCACGCTGCTGAGGAGATGGCGGTCCGGGTGATCTCGGCGGCGACGTCGATAGACCCTACGATTGGTTGA

Upstream 100 bases:

>100_bases
GCAACGCACTGAGCCGGCCCGAGTAACGAGCGTCGTCGATGGTGGCAACCGTGGCTGATCTGAACCTCATTTGCCGTCTT
TCTTCCCCAGAGGAGTACTC

Downstream 100 bases:

>100_bases
GGAGATATCTCATGTCACTGCGGGAACCTGTCGAGCTACTTGATCCCAGCGCCGTAGGGCCGGTCTACTTCATCGCCATC
GGCGGAGCCGGAATGAGCGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVPLPRTVNADLFKVPARLAGAV
RKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIHEQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLR
SQITDLADASGQARAERCARARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRIT
DELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQARNATSAVDAGAGVVVANADLD
VERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRVISAATSIDPTIG

Sequences:

>Translated_372_residues
MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVPLPRTVNADLFKVPARLAGAV
RKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIHEQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLR
SQITDLADASGQARAERCARARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRIT
DELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQARNATSAVDAGAGVVVANADLD
VERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRVISAATSIDPTIG
>Mature_372_residues
MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVPLPRTVNADLFKVPARLAGAV
RKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIHEQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLR
SQITDLADASGQARAERCARARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRIT
DELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQARNATSAVDAGAGVVVANADLD
VERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRVISAATSIDPTIG

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=321, Percent_Identity=36.7601246105919, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PROAC (Q6A9Q2)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055472.1
- ProteinModelPortal:   Q6A9Q2
- SMR:   Q6A9Q2
- GeneID:   2932753
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0758
- NMPDR:   fig|267747.1.peg.749
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- BioCyc:   PACN267747:PPA0758-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38291; Mature: 38291

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVP
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCC
LPRTVNADLFKVPARLAGAVRKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEE
EQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLRSQITDLADASGQARAERCAR
CCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHEECCCHHHHHHHHHCCCCHHHHHHHHH
ARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRIT
HHHHCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHH
DELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQAR
HHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCEEEEECCCCCCHHHH
NATSAVDAGAGVVVANADLDVERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRV
CHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ISAATSIDPTIG
HHHHHCCCCCCC
>Mature Secondary Structure
MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVP
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCC
LPRTVNADLFKVPARLAGAVRKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEE
EQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLRSQITDLADASGQARAERCAR
CCCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHEECCCHHHHHHHHHCCCCHHHHHHHHH
ARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRIT
HHHHCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHH
DELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQAR
HHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCEEEEECCCCCCHHHH
NATSAVDAGAGVVVANADLDVERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRV
CHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ISAATSIDPTIG
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA