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The map label for this gene is glmU [H]

Identifier: 50842014

GI number: 50842014

Start: 583502

End: 584800

Strand: Direct

Name: glmU [H]

Synonym: PPA0530

Alternate gene names: 50842014

Gene position: 583502-584800 (Clockwise)

Preceding gene: 50842012

Following gene: 50842015

Centisome position: 22.79

GC content: 61.74

Gene sequence:

>1299_bases
GTGACGCCGAGCCCGTCCACTGACCGAGCCGAGATCGACGGAGTGGCTGCCGTCATCGTGTTAGCCGCCGGCGGCGGCAC
TCGCATGAAGTCGACGAAGTCTAAGCTGCTGCACGAGGTTGCTGGTCGGCCAATGTTGTCGTGGGCGATCGGAGCGGCTC
GCGGACTTAACCCGGAACATCTCGTCGTGGTCGTGGGTCACCGTCGCGAGCAGGTAGAGGCCCATCTCGCTGAGGACGCC
CCCGACGTCACCACCGCGGTCCAGGCAGAGCAAAAAGGCACTGGGCACGCCGTCGCATGCGGGCTCGAGGGATTGGACGA
GCTTCACGGTGAGGTCGTCGTCACCTACGGCGACGTCCCTATGCTTACCGGTGAGACCCTTCAGCGGATGGTTGAGGTGC
ACCGCGAGCGCCGCAATCTTGTTACCGTTCTTACGGCCGAGGTAGAGGACCCCACGGGTTACGGACGAATCCTGCGAGGG
GGAGAGGCTGTTGTAGGAATCGTCGAGCATAAAGACGCCGATGAGGCCCAGCGAGCCGTTCGCGAGATCAATTCCGGTAT
TTATGTTTTCGATGCCGAAGCTTTGCGCGAGGGCGTCTCCAAGCTTTCTAACGACAACGTTCAGGGTGAGTATTACCTCA
CCGACGTCGTCACCATGGCTGCTGACGGCACTGTCGAGGTTCCTGGCCGCGGTCGCGTGGGCGCCTTCCGTATCGACGAC
GTGTGGCAAACCGAGGGGGTTAACGACCGGGTCCAGCTGGCCCGCATGAACGCCGAGGTTAATCGCCGTATCGTCACTGG
ATGGATGCGTGCTGGGGTTACCATCATTGATCCCACTTCGACATGGATCCAGCCGGATGTTGACCTCGCTAATGACGTCA
CTTTATATCCCGGGGTATTCCTCAACGGGGCTACCACCATTGGAGCTGGGGCCACGGTTGGCCCGGACGTTACTGTCACC
GACTCCGAGATTCGTGAGGAAGCCACCGTCACCCGTTCCGAGGTCACCCTCGCGGTCGTCGGTGAGGGGGTGCGGGTTGG
CCCGTTCTCCAACATCCGTCCTGGTTCCGTACTCGACCGTGACGCCAAAGTCGGAGCCTTTGTTGAAACCAAGAACACCC
ACATCGGAACCGAAGCGGCCATCCCCCACATGGCCTACGTTGGCGATTCCGAGGTGACTGCAGGATCCTCCATTGTTGCC
GGATCCGTCCTTTCCCGGGAGTGCGCCGCTCCCGCCACCGTCTCGGACATCACGTCCGACAGCCAAGACGACACCCTGAA
CCCGGAGGCTGACCAGTGA

Upstream 100 bases:

>100_bases
CTGCCCGGGGAGCTCGTTGATCCCGCTCCCGCAGTGCGGTGTAACCGAGTGGCGGCTAGAGTAAACCTTGCATGCCACAT
CCGAACCTGGGGGGAGCACC

Downstream 100 bases:

>100_bases
GTGGAACCACCCGTCCGAACAACAAGCACCTCATGATTTGCTCAGGACGGGCCTATCCCGAACTTGCTGAGCAGATCGCT
GCCGAACTCGGCGTCGAGCT

Product: N-acetylglucosamine-1-phosphate uridyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTPSPSTDRAEIDGVAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEHLVVVVGHRREQVEAHLAEDA
PDVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVPMLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRG
GEAVVGIVEHKDADEAQRAVREINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDD
VWQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVFLNGATTIGAGATVGPDVTVT
DSEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDRDAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVA
GSVLSRECAAPATVSDITSDSQDDTLNPEADQ

Sequences:

>Translated_432_residues
MTPSPSTDRAEIDGVAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEHLVVVVGHRREQVEAHLAEDA
PDVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVPMLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRG
GEAVVGIVEHKDADEAQRAVREINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDD
VWQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVFLNGATTIGAGATVGPDVTVT
DSEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDRDAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVA
GSVLSRECAAPATVSDITSDSQDDTLNPEADQ
>Mature_431_residues
TPSPSTDRAEIDGVAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEHLVVVVGHRREQVEAHLAEDAP
DVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVPMLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRGG
EAVVGIVEHKDADEAQRAVREINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDDV
WQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVFLNGATTIGAGATVGPDVTVTD
SEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDRDAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVAG
SVLSRECAAPATVSDITSDSQDDTLNPEADQ

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=395, Percent_Identity=34.9367088607595, Blast_Score=225, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 45761; Mature: 45629

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSPSTDRAEIDGVAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEH
CCCCCCCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LVVVVGHRREQVEAHLAEDAPDVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVP
EEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECHHHHHHCCCCEEEEECCCC
MLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRGGEAVVGIVEHKDADEAQRAV
CCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHEEECCCEEEEEEECCCHHHHHHHH
REINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDD
HHHCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEECCCCCCEEEEEECC
VWQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVF
CCCCCCCCCHHHEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEECCCEE
LNGATTIGAGATVGPDVTVTDSEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDR
ECCCEECCCCCCCCCCEEEEHHHHHHHHHEEHHHEEEEEECCCEEECCCCCCCCCCCCCC
DAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVAGSVLSRECAAPATVSDITSD
CCCCCEEEEECCCCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
SQDDTLNPEADQ
CCCCCCCCCCCC
>Mature Secondary Structure 
TPSPSTDRAEIDGVAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEH
CCCCCCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LVVVVGHRREQVEAHLAEDAPDVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVP
EEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECHHHHHHCCCCEEEEECCCC
MLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRGGEAVVGIVEHKDADEAQRAV
CCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHEEECCCEEEEEEECCCHHHHHHHH
REINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDD
HHHCCCEEEEEHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEECCCCCCEEEEEECC
VWQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVF
CCCCCCCCCHHHEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEECCCEE
LNGATTIGAGATVGPDVTVTDSEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDR
ECCCEECCCCCCCCCCEEEEHHHHHHHHHEEHHHEEEEEECCCEEECCCCCCCCCCCCCC
DAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVAGSVLSRECAAPATVSDITSD
CCCCCEEEEECCCCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
SQDDTLNPEADQ
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA