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The map label for this gene is glmM

Identifier: 50086460

GI number: 50086460

Start: 3426451

End: 3427782

Strand: Reverse

Name: glmM

Synonym: ACIAD3502

Alternate gene names: 50086460

Gene position: 3427782-3426451 (Counterclockwise)

Preceding gene: 50086461

Following gene: 50086459

Centisome position: 95.25

GC content: 43.02

Gene sequence:

>1332_bases
ATGAGTTATTTTGGAACCGATGGCATTCGTGGAAAATTCGGTGAGATGCCGATCACCCCTGAATTTGCATTAAAATTAGG
GTTTGCCGCTGGAAAAGTATTAAAACGAACAAGTCCAATTAATAAGCCTATTGTTGTTTTGGGTAAAGATACCCGTTTAT
CTGGTTATATTTTAGAGTCAGCTTTACAGGCAGGTTTAAATGCGGCAGGCGTTTATGTGCATTTACTGGGGCCTTTGCCA
ACCCCTGCAATTGCGCATCTAACGCGTGCTTTACATGCCGATGCAGGTATTGTGATTTCTGCATCTCATAATCCCTACTT
TGATAATGGCATTAAGTTTTTCTCTGGTGAAGGTAAAAAACTACCTGATTCACTTCAAGATGAGATTAATCAGGAACTTG
AGCACGAGTTGCATATTGAAGACACCGCAAATTTGGGTAAAAGTGTGCGTCTCATCGATGCTAATGGGCGCTATATCGAG
TTTTGTAAATCAACTTTTCCGTATCATTTTGACTTACGAAATCTGACCATTGTGGTGGATTGTGCCAATGGTGCAGCCTA
TAACGTAGGTCCTTCGGTTTTTCGTGAGCTCGGTGCAAAAGTGATTGCACTGTATAATGATCCGAATGGTATGAACATCA
ATGAGCATTGTGGTTCAACCCATCCAGAAAATCTGCAAAAAGCAGTGGTTCATTACAAGGCCGATTTAGGCATTGCTTTT
GATGGTGATGCAGACCGAGTGATTCTGGTTGATAAATTCGGAGAGTTGGTCGATGGAGATCATATTCTATATATCTTGGC
GACTCAGGCCAAAAAGAAACCTGCTGGCATTGTCGGCACGGTCATGAGTAATATGGCTTTGGAATTGGCTTTGGCAAAAG
CTGATGTGCCGTTTATACGCGCCAAGGTCGGAGATCGCTATGTGTTACAGGCACTTGAAGAAAATGATTGGGTGACTGGA
GGCGAGCCTTCTGGACATATTTTGACCTTAGACAAGAGTACAACGGGTGATGCCATTATTGCGGCATTACAAGTGTTGAC
GGTTATGGTTGAGCAAAATAAAGCTTTACATGAACTGGTAACTGGTTTTGAATTATTCCCGCAAGTACTGGTCAATGTGC
GTCTGGATCAAATGATGGATCCATACTCGGTCCCCGCCTTAGTCAGTGAATTTGAACAGGCAGAAGCACAGTTGAAAGGA
CGTGGACGTCTATTGATTCGTAAATCAGGTACCGAACCTGTCATTCGTGTGATGGTTGAAGGTGACAATCAAAAAGAAGT
CACTGACTTGGCTCATCGTTTGGCAGAATCTGTACGTACACATGCCGCCTAA

Upstream 100 bases:

>100_bases
GAATAAAAAACGCCGTCAGTCCACTGACGGCGTTTTTGTTTTGGTGTAAAGTAAACAGATAGATGGTGGCTTCACCACAA
GATAAAGAAGTGAGTCAAAG

Downstream 100 bases:

>100_bases
GGTAATCAATTCGCTATGAAAGATGTAATTAAAGATCTCAGCGAACTTCGCATGAGTTATGAAAAAGGTGAACTACACGA
AGCGCAAGTGGACACCCATC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSYFGTDGIRGKFGEMPITPEFALKLGFAAGKVLKRTSPINKPIVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLP
TPAIAHLTRALHADAGIVISASHNPYFDNGIKFFSGEGKKLPDSLQDEINQELEHELHIEDTANLGKSVRLIDANGRYIE
FCKSTFPYHFDLRNLTIVVDCANGAAYNVGPSVFRELGAKVIALYNDPNGMNINEHCGSTHPENLQKAVVHYKADLGIAF
DGDADRVILVDKFGELVDGDHILYILATQAKKKPAGIVGTVMSNMALELALAKADVPFIRAKVGDRYVLQALEENDWVTG
GEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVTGFELFPQVLVNVRLDQMMDPYSVPALVSEFEQAEAQLKG
RGRLLIRKSGTEPVIRVMVEGDNQKEVTDLAHRLAESVRTHAA

Sequences:

>Translated_443_residues
MSYFGTDGIRGKFGEMPITPEFALKLGFAAGKVLKRTSPINKPIVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLP
TPAIAHLTRALHADAGIVISASHNPYFDNGIKFFSGEGKKLPDSLQDEINQELEHELHIEDTANLGKSVRLIDANGRYIE
FCKSTFPYHFDLRNLTIVVDCANGAAYNVGPSVFRELGAKVIALYNDPNGMNINEHCGSTHPENLQKAVVHYKADLGIAF
DGDADRVILVDKFGELVDGDHILYILATQAKKKPAGIVGTVMSNMALELALAKADVPFIRAKVGDRYVLQALEENDWVTG
GEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVTGFELFPQVLVNVRLDQMMDPYSVPALVSEFEQAEAQLKG
RGRLLIRKSGTEPVIRVMVEGDNQKEVTDLAHRLAESVRTHAA
>Mature_442_residues
SYFGTDGIRGKFGEMPITPEFALKLGFAAGKVLKRTSPINKPIVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLPT
PAIAHLTRALHADAGIVISASHNPYFDNGIKFFSGEGKKLPDSLQDEINQELEHELHIEDTANLGKSVRLIDANGRYIEF
CKSTFPYHFDLRNLTIVVDCANGAAYNVGPSVFRELGAKVIALYNDPNGMNINEHCGSTHPENLQKAVVHYKADLGIAFD
GDADRVILVDKFGELVDGDHILYILATQAKKKPAGIVGTVMSNMALELALAKADVPFIRAKVGDRYVLQALEENDWVTGG
EPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVTGFELFPQVLVNVRLDQMMDPYSVPALVSEFEQAEAQLKGR
GRLLIRKSGTEPVIRVMVEGDNQKEVTDLAHRLAESVRTHAA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=441, Percent_Identity=56.6893424036281, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1788361, Length=452, Percent_Identity=30.9734513274336, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ACIAD (Q6F717)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047970.1
- ProteinModelPortal:   Q6F717
- SMR:   Q6F717
- STRING:   Q6F717
- GeneID:   2881137
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3502
- NMPDR:   fig|62977.3.peg.3163
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q6F717
- ProtClustDB:   PRK10887
- BioCyc:   ASP62977:ACIAD3502-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48182; Mature: 48051

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFGTDGIRGKFGEMPITPEFALKLGFAAGKVLKRTSPINKPIVVLGKDTRLSGYILES
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHH
ALQAGLNAAGVYVHLLGPLPTPAIAHLTRALHADAGIVISASHNPYFDNGIKFFSGEGKK
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCC
LPDSLQDEINQELEHELHIEDTANLGKSVRLIDANGRYIEFCKSTFPYHFDLRNLTIVVD
CCHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCEEEEHHHCCCEEEECCCEEEEEE
CANGAAYNVGPSVFRELGAKVIALYNDPNGMNINEHCGSTHPENLQKAVVHYKADLGIAF
CCCCCEECCCHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCHHHHHHHHHHEECCEEEEE
DGDADRVILVDKFGELVDGDHILYILATQAKKKPAGIVGTVMSNMALELALAKADVPFIR
CCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
AKVGDRYVLQALEENDWVTGGEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELV
ECCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
TGFELFPQVLVNVRLDQMMDPYSVPALVSEFEQAEAQLKGRGRLLIRKSGTEPVIRVMVE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
GDNQKEVTDLAHRLAESVRTHAA
CCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYFGTDGIRGKFGEMPITPEFALKLGFAAGKVLKRTSPINKPIVVLGKDTRLSGYILES
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHH
ALQAGLNAAGVYVHLLGPLPTPAIAHLTRALHADAGIVISASHNPYFDNGIKFFSGEGKK
HHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCC
LPDSLQDEINQELEHELHIEDTANLGKSVRLIDANGRYIEFCKSTFPYHFDLRNLTIVVD
CCHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCEEEEHHHCCCEEEECCCEEEEEE
CANGAAYNVGPSVFRELGAKVIALYNDPNGMNINEHCGSTHPENLQKAVVHYKADLGIAF
CCCCCEECCCHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCHHHHHHHHHHEECCEEEEE
DGDADRVILVDKFGELVDGDHILYILATQAKKKPAGIVGTVMSNMALELALAKADVPFIR
CCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
AKVGDRYVLQALEENDWVTGGEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELV
ECCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
TGFELFPQVLVNVRLDQMMDPYSVPALVSEFEQAEAQLKGRGRLLIRKSGTEPVIRVMVE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
GDNQKEVTDLAHRLAESVRTHAA
CCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA