Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 50086341

GI number: 50086341

Start: 3271106

End: 3272224

Strand: Reverse

Name: mraY

Synonym: ACIAD3363

Alternate gene names: 50086341

Gene position: 3272224-3271106 (Counterclockwise)

Preceding gene: 50086342

Following gene: 50086340

Centisome position: 90.93

GC content: 43.97

Gene sequence:

>1119_bases
ATGCTGTTATGGTTGTTTGAACATCTATCGGGCTACAACAGCTCGTTCCAAGTTATTCGTTATTTAACATTACGTTCATT
GCTAAGTATTTTGACGTCACTTGCAATTGGCCTAATGCTTGGTCCGGTGATGATTCGTAAACTTCAGGCATTAAAATATG
GTCAGGCAGTCAGTTCGTTTGCACCTGAAAACCATGCCAAAAAAATGGGTACACCAACCATGGGTGGCGTATTAATCCTG
ATGTCGATTGGGATTAGTACCTTACTCTGGGCCGATTTATCCAACCCTTATGTCTGGATTGTACTGGGTGTTATGGTGGT
GTTTGGTGCTGTGGGCTGGGCCGATGACTGGATCAAGATCCGTTATAAAGATAATGCTGGCTTGCCTGCTCGCAAAAAGT
TCTTCTGGACATCGGTGGCTTCGCTTGGGGCGGGTATTTCATTGTATGTGATTGCCCAGAATCAACCCAATCCAATTCAC
ACGGCAAACATGCTGGATTTATTAATTCCATTCTTTAAAAATTTGTCGATCCCACTTTCGGCTGTGCCACTTGGAATTGC
TTTTATTATTTTCACTTATCTGGTGATCAATGGTGCCTCCAATGCAGTCAATCTCACCGATGGTCTTGATGGCCTAGCAA
TTATGCCCATCGTGATGGTTGCTGCAGGGTTGGGTGTATTTGCCTATTTGGCGGGTGACATTCGTTTTGCCAATTATCTG
CACATCCCTTATGTAAAATATACGTCTGAGCTGGTGGTCATCTGTTCTGCCATGGTGGGTGCAGGTTTAGCATTCTTATG
GTACAACGCACACCCTGCACAAATTTTTATGGGTGATGTTGGTGCGCTGGCACTCGGTGCGATGTTGGGTACCATTGCGG
TCATGGTCCGTCAGGAAATTGTATTTGCGATCATGGGTGGCGTATTTGTAATGGAAGCAATTTCAGTTTTCTTGCAAATT
GGTTCATTGCGCATGCGAAACAAACGTGTATTTCTGATGGCGCCTTTACATCACCACTATGAAAAGCAAGGCTGGAAAGA
AACACAGGTCGTGACCCGTTTTTGGATTATTACGATTATGCTGGTGGTTTTGGGTCTAATGACTTTAAAATTACGTTAA

Upstream 100 bases:

>100_bases
AATTCAACAACATCAACCCCAGTCCATGAGTTTCCTGTTTAAAGGTTCTCGTTATACCCATATGGAAACGTTGATGGCTG
ACTTGATGGAGAAACTTTAA

Downstream 100 bases:

>100_bases
GTTAAGCTGTCACTATATAATTGAAGAAAGCCGGCCACGCCGGCTTTTTTATTAGGAAAATGATGATGAATGTGTTGATG
TGCCCTGTGTGTCGTGGTGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLLWLFEHLSGYNSSFQVIRYLTLRSLLSILTSLAIGLMLGPVMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGVLIL
MSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGISLYVIAQNQPNPIH
TANMLDLLIPFFKNLSIPLSAVPLGIAFIIFTYLVINGASNAVNLTDGLDGLAIMPIVMVAAGLGVFAYLAGDIRFANYL
HIPYVKYTSELVVICSAMVGAGLAFLWYNAHPAQIFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAISVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVTRFWIITIMLVVLGLMTLKLR

Sequences:

>Translated_372_residues
MLLWLFEHLSGYNSSFQVIRYLTLRSLLSILTSLAIGLMLGPVMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGVLIL
MSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGISLYVIAQNQPNPIH
TANMLDLLIPFFKNLSIPLSAVPLGIAFIIFTYLVINGASNAVNLTDGLDGLAIMPIVMVAAGLGVFAYLAGDIRFANYL
HIPYVKYTSELVVICSAMVGAGLAFLWYNAHPAQIFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAISVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVTRFWIITIMLVVLGLMTLKLR
>Mature_372_residues
MLLWLFEHLSGYNSSFQVIRYLTLRSLLSILTSLAIGLMLGPVMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGVLIL
MSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGISLYVIAQNQPNPIH
TANMLDLLIPFFKNLSIPLSAVPLGIAFIIFTYLVINGASNAVNLTDGLDGLAIMPIVMVAAGLGVFAYLAGDIRFANYL
HIPYVKYTSELVVICSAMVGAGLAFLWYNAHPAQIFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAISVFLQI
GSLRMRNKRVFLMAPLHHHYEKQGWKETQVVTRFWIITIMLVVLGLMTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=372, Percent_Identity=54.5698924731183, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_ACIAD (Q6F7D6)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047851.1
- STRING:   Q6F7D6
- GeneID:   2878501
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3363
- NMPDR:   fig|62977.3.peg.3044
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q6F7D6
- ProtClustDB:   PRK00108
- BioCyc:   ASP62977:ACIAD3363-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 40889; Mature: 40889

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1aea91b4)-; HASH(0x1a936d54)-; HASH(0x1b4b4f70)-; HASH(0x1a84db64)-; HASH(0x1a891640)-; HASH(0x1ac6ce30)-; HASH(0x1aad3b9c)-; HASH(0x1a91a060)-; HASH(0x1aebe24c)-; HASH(0x1b1150b4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLWLFEHLSGYNSSFQVIRYLTLRSLLSILTSLAIGLMLGPVMIRKLQALKYGQAVSSF
CEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APENHAKKMGTPTMGGVLILMSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKI
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
RYKDNAGLPARKKFFWTSVASLGAGISLYVIAQNQPNPIHTANMLDLLIPFFKNLSIPLS
EEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHH
AVPLGIAFIIFTYLVINGASNAVNLTDGLDGLAIMPIVMVAAGLGVFAYLAGDIRFANYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
HIPYVKYTSELVVICSAMVGAGLAFLWYNAHPAQIFMGDVGALALGAMLGTIAVMVRQEI
ECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
VFAIMGGVFVMEAISVFLQIGSLRMRNKRVFLMAPLHHHYEKQGWKETQVVTRFWIITIM
HHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHH
LVVLGLMTLKLR
HHHHHHHHHCCH
>Mature Secondary Structure
MLLWLFEHLSGYNSSFQVIRYLTLRSLLSILTSLAIGLMLGPVMIRKLQALKYGQAVSSF
CEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APENHAKKMGTPTMGGVLILMSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKI
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
RYKDNAGLPARKKFFWTSVASLGAGISLYVIAQNQPNPIHTANMLDLLIPFFKNLSIPLS
EEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHH
AVPLGIAFIIFTYLVINGASNAVNLTDGLDGLAIMPIVMVAAGLGVFAYLAGDIRFANYL
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
HIPYVKYTSELVVICSAMVGAGLAFLWYNAHPAQIFMGDVGALALGAMLGTIAVMVRQEI
ECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
VFAIMGGVFVMEAISVFLQIGSLRMRNKRVFLMAPLHHHYEKQGWKETQVVTRFWIITIM
HHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHH
LVVLGLMTLKLR
HHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA