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The map label for this gene is rrm [H]

Identifier: 50086340

GI number: 50086340

Start: 3270219

End: 3271040

Strand: Reverse

Name: rrm [H]

Synonym: ACIAD3362

Alternate gene names: 50086340

Gene position: 3271040-3270219 (Counterclockwise)

Preceding gene: 50086341

Following gene: 50086338

Centisome position: 90.9

GC content: 43.31

Gene sequence:

>822_bases
ATGAATGTGTTGATGTGCCCTGTGTGTCGTGGTGAATTGGCATTACAACACGCCACTTGGCGTTGTAAACAAGGCCATAG
CTATGATGTGGCAAAACAGGGTTATGTAAACTTGCATGTGGTGCAGCATAAGCATAGTAAGACACCTGGTGATACACCTG
AATCTGTTCAGGCACGCCGTGAGTTTCTCTCTGGTGGGTTCTATCAGCCGTTACGTGATGCAATTGAGGCCCAGATATCC
GCATTGAAGGTAAAAACGATTCTAGATATTGGTTGTGGTGAAGGTTATTACACCGATGCCATGCAAAAGCATGCGAAGGT
TTGTATCGGTCTGGATATTGCAAAAACAGCCGTACAGCGGGCTGCCAAAACCAATGCTGATGTGACATGGGTGGTGGGTA
CAGGAGCGATCTTGCCTGTTCTTGATCAATCGATGGATGTGTGTAGCAGTCTTTTTAGCCCCATTCCCAAAGCAGAAATT
TTGCGGGTGCTGAAGCCAGAAGGTCATCTAATTGTTGTGACACCTGCACCTTCGCATCTTTATAATTTGCGTGCAGCGCT
GTTTGATGAAGTTAAACTGCATGAGCCAGAAAAATTTGTTGAGCAGTTGAATGATGGCTTAGCATTGGTGCAACAACACA
TGGTGGAAAGTACCTTTGAACTTGAGCAGGCGCAATTAAAAAATTTGATTGCCATGACGCCTTATGCTTACAAGGCTAAA
CCAGAAAAACGAACAGAGATAGAAAATCAGTCTTGTATAAAACTGACCGCATGTTTCCAGATTTATATCTTTCAAAAAAT
AAAAAAACAGCCATCAATTTGA

Upstream 100 bases:

>100_bases
TGGTTTTGGGTCTAATGACTTTAAAATTACGTTAAGTTAAGCTGTCACTATATAATTGAAGAAAGCCGGCCACGCCGGCT
TTTTTATTAGGAAAATGATG

Downstream 100 bases:

>100_bases
TGGCTGTTTTTTTTATGTCACTTGATTAATCAATCCTTCCAGTGCATCGCCTCGTTTGGGCGTCTCATTTTTCTTTGGTG
AGGATGGCTGTTGCTGCATA

Product: 23S ribosomal RNA G745 methyltransferase

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNVLMCPVCRGELALQHATWRCKQGHSYDVAKQGYVNLHVVQHKHSKTPGDTPESVQARREFLSGGFYQPLRDAIEAQIS
ALKVKTILDIGCGEGYYTDAMQKHAKVCIGLDIAKTAVQRAAKTNADVTWVVGTGAILPVLDQSMDVCSSLFSPIPKAEI
LRVLKPEGHLIVVTPAPSHLYNLRAALFDEVKLHEPEKFVEQLNDGLALVQQHMVESTFELEQAQLKNLIAMTPYAYKAK
PEKRTEIENQSCIKLTACFQIYIFQKIKKQPSI

Sequences:

>Translated_273_residues
MNVLMCPVCRGELALQHATWRCKQGHSYDVAKQGYVNLHVVQHKHSKTPGDTPESVQARREFLSGGFYQPLRDAIEAQIS
ALKVKTILDIGCGEGYYTDAMQKHAKVCIGLDIAKTAVQRAAKTNADVTWVVGTGAILPVLDQSMDVCSSLFSPIPKAEI
LRVLKPEGHLIVVTPAPSHLYNLRAALFDEVKLHEPEKFVEQLNDGLALVQQHMVESTFELEQAQLKNLIAMTPYAYKAK
PEKRTEIENQSCIKLTACFQIYIFQKIKKQPSI
>Mature_273_residues
MNVLMCPVCRGELALQHATWRCKQGHSYDVAKQGYVNLHVVQHKHSKTPGDTPESVQARREFLSGGFYQPLRDAIEAQIS
ALKVKTILDIGCGEGYYTDAMQKHAKVCIGLDIAKTAVQRAAKTNADVTWVVGTGAILPVLDQSMDVCSSLFSPIPKAEI
LRVLKPEGHLIVVTPAPSHLYNLRAALFDEVKLHEPEKFVEQLNDGLALVQQHMVESTFELEQAQLKNLIAMTPYAYKAK
PEKRTEIENQSCIKLTACFQIYIFQKIKKQPSI

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=266, Percent_Identity=40.9774436090226, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30470; Mature: 30470

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLMCPVCRGELALQHATWRCKQGHSYDVAKQGYVNLHVVQHKHSKTPGDTPESVQARR
CCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
EFLSGGFYQPLRDAIEAQISALKVKTILDIGCGEGYYTDAMQKHAKVCIGLDIAKTAVQR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHEEECHHHHHHHHHH
AAKTNADVTWVVGTGAILPVLDQSMDVCSSLFSPIPKAEILRVLKPEGHLIVVTPAPSHL
HHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCHHH
YNLRAALFDEVKLHEPEKFVEQLNDGLALVQQHMVESTFELEQAQLKNLIAMTPYAYKAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PEKRTEIENQSCIKLTACFQIYIFQKIKKQPSI
CCHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVLMCPVCRGELALQHATWRCKQGHSYDVAKQGYVNLHVVQHKHSKTPGDTPESVQARR
CCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
EFLSGGFYQPLRDAIEAQISALKVKTILDIGCGEGYYTDAMQKHAKVCIGLDIAKTAVQR
HHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHEEECHHHHHHHHHH
AAKTNADVTWVVGTGAILPVLDQSMDVCSSLFSPIPKAEILRVLKPEGHLIVVTPAPSHL
HHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCHHH
YNLRAALFDEVKLHEPEKFVEQLNDGLALVQQHMVESTFELEQAQLKNLIAMTPYAYKAK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PEKRTEIENQSCIKLTACFQIYIFQKIKKQPSI
CCHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]