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The map label for this gene is rnr [H]

Identifier: 50086178

GI number: 50086178

Start: 3107961

End: 3110414

Strand: Direct

Name: rnr [H]

Synonym: ACIAD3179

Alternate gene names: 50086178

Gene position: 3107961-3110414 (Clockwise)

Preceding gene: 50086177

Following gene: 50086179

Centisome position: 86.37

GC content: 42.22

Gene sequence:

>2454_bases
ATGCTAAACTTATCTTCTATTATGAAGCCAAATGAAATTATGAAAAACTGGATCGATCCTGAAGCAAAAGCGGAAGCTGA
ACGTTACGATAATCCTATTCCTAGCCGAACTCTTATTCTTACTACATTAGAACAACTTGATCTGCCACAGTCGCATGCCG
AGCTGGTCGATCACTTTGATATTCATGATCAAAAAAGTATAGATGCTTTAAGCCATCGCCTGATTGCCATGGTACGCGAT
GGGCAACTGTCTAAAGATGGTTTTAAATTTCAGCCGATTGGTGAACAACCTACATTTGATGCAACGGTATATATCAATAA
TAAAGGTTTCGGTTCTGCACATATTGATGGGCAAAATGATTTGCTCCTGCCAGAACGTGAATTACGCCTAGTCTTTAATG
GTGATCGTGTTAAAGTTCGTCAAACCTCAGTCGATCGTAAAGGTAAAGCTTGGGGCTTTATTACAGAAGTAACGCAACAC
CGCGTTAAGCAGTTGATTGGTAAACTGGCTGTGCACGAAGGTGAATATTTCTTGCAGCCAAGCGCGCCCAATGCACATCA
GCCCATTCCTCTTGAAAAAGAACTTATTGAACATGCTCAGGCCAAGGTAGGTGAGAATTTACGTGTTGCGATTGATGATT
ATCCAACACGTGAAGAATTCTCGACAGGTCATATTATTCAGTCGATGTCTGATAAAGCCGATACGGAAATTATTATTCCA
CAAACCATTCTGGAATTTGGCTTACCTTATGAATTTCCAGAAGAAGTGGTGAAAGATGCCGAAAGCTTTAAAGAACCATC
GAAAAAGGATATTGAAGGACGTATCGACTTACGTGATTTGCCTTTGGTCACCATTGATGGTGAAGATGCACGTGACTTTG
ATGATGCTGTTTATGCCGAAAAACGTTCAGGTGGCGGTTATCGTGTTGTGGTTGCAATTGCAGATGTCAGTCATTATGTA
CGTCTTGGTAAGCCTTTGGATGATGAGGCCCAAGAACGCGGTACATCCGTTTATTTCCCGCATTTTGTCTTGCCTATGCT
ACCAGAAGCATTATCCAATGGCTTATGTTCTTTAAATCCGCATGTTGATCGCTTATGTATGGTGTGTGATCTCAAGCTGT
CACGTGCTGGACGGGTTATGAGCTACGAGTTCTACCCTTCTGTGATGCATTCAAAAGCACGCCTGACCTATACACAGGTC
GGTAACTATTTTGATGGACAAACAGATGCCATTCCAGATGATAAAAATATTCAAAAGTCTTTAAATACGCTATTCCAACT
CTATCAAACACTCAAAGGTTTACGTGCCAAACGTCATGCGATGGAGTTCGAAACCATCGAAACCTATATGACGTTTGATG
AATTAGGTGGTATCAAGGAAATTCTGCCACGTACGCGTAATGAAGCGCATAAACTGATTGAAGAATGCATGCTGCTTGCC
AATGTTGCAGCGGCAGAATTTTCCCTCCAGCATGATATTCCAATGCTGTATCGCGTGCATGAAGCACCAGAGTTTTCACG
GATTCAAAAAGTGAAGGACTTTGTCAAACTACTGGGTTTACCTTTCCCAGATCAGCCGACTCAGGCAGATTATCAGCGCG
TGATTGAAGCGACCAAAGACCGTATTGATGCACCAAGTATCCATGCAGTGTTATTGCGCTCAATGATGCAAGCTTACTAC
GGCGCCAAAAATGCAGGACATTATGGTTTAGCATACGAGGCTTATACCCACTTCACCTCACCAATCCGCCGTTATCCAGA
TTTGTTACTACATCGTGCAATCAAAGCTCATCTTCAACAAAAACCATATCCACTTTCTGGTGCAGCACTAGATGATGCAG
GTGAACAATTTTCCCGTACCGAACGTCGTGCCGATGAAGCATCACGTAGTGTGACCACTTGGTTAAAATGCCATTATATG
AAACAGCATCTTGGCGAAGAGTTTATTGGAATCATCAGTGCTGTTACCGAATTTGGCTTGTTTGTTACGCTTAAAGATTT
ATATGTAGATGGCATGATTCATGTCAGTCAGTTAGGTGATGATTTCTTCCTCTATGACCAAGCCAGTCAGAGCCTGGTCG
GTCAGAATCGTGGCCAGATTTTTGGCTTGGGTGATGAAGTTAAAATCAAGGTTGCAGCTGTTAATCTAGATGAGCGTAAA
ATTGATTTCGAACTGATGCAGCAGATTACACATGCGGGGCGTGTCATTCGCCAGAAAGCACCGCGTAGCTCTAAGACTCA
AGCAACAGAGCAAGTCTTTAATGTGCCAAGTGAAACCACCTCTACGCAAGAACGTGACACACGCAAAAAAGAAAAGTCAA
AGAGCAAGCCAAGTTCTTATGCTAAAAAATCGGCAAAAAAATCTTCTCCTGCATCGGTCAGTAAGCCCGTAAAAGAGAAG
AAAAAAGTCAAAGTTAAGAAGAAAAAATCAAATGCCAAACCTAAAAGTGAATGA

Upstream 100 bases:

>100_bases
TATGAGTTGATAATATAGTCCAATGTTCCGAGATTTTCGGTTCGAACAGGCATAACACAATCTTGCAATCCATCACGTGC
AGTCTGTGATTGTATGACGT

Downstream 100 bases:

>100_bases
TCCAACTCAATCACTTTAGACGCATTTGAATTTAAAGAGATGACTGCCGTTTAATCATGAATTAGACGGCATTTTTATTA
AGTTATGTTGATATCTAAAT

Product: exoribonuclease R

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 817; Mature: 817

Protein sequence:

>817_residues
MLNLSSIMKPNEIMKNWIDPEAKAEAERYDNPIPSRTLILTTLEQLDLPQSHAELVDHFDIHDQKSIDALSHRLIAMVRD
GQLSKDGFKFQPIGEQPTFDATVYINNKGFGSAHIDGQNDLLLPERELRLVFNGDRVKVRQTSVDRKGKAWGFITEVTQH
RVKQLIGKLAVHEGEYFLQPSAPNAHQPIPLEKELIEHAQAKVGENLRVAIDDYPTREEFSTGHIIQSMSDKADTEIIIP
QTILEFGLPYEFPEEVVKDAESFKEPSKKDIEGRIDLRDLPLVTIDGEDARDFDDAVYAEKRSGGGYRVVVAIADVSHYV
RLGKPLDDEAQERGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRAGRVMSYEFYPSVMHSKARLTYTQV
GNYFDGQTDAIPDDKNIQKSLNTLFQLYQTLKGLRAKRHAMEFETIETYMTFDELGGIKEILPRTRNEAHKLIEECMLLA
NVAAAEFSLQHDIPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQRVIEATKDRIDAPSIHAVLLRSMMQAYY
GAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLQQKPYPLSGAALDDAGEQFSRTERRADEASRSVTTWLKCHYM
KQHLGEEFIGIISAVTEFGLFVTLKDLYVDGMIHVSQLGDDFFLYDQASQSLVGQNRGQIFGLGDEVKIKVAAVNLDERK
IDFELMQQITHAGRVIRQKAPRSSKTQATEQVFNVPSETTSTQERDTRKKEKSKSKPSSYAKKSAKKSSPASVSKPVKEK
KKVKVKKKKSNAKPKSE

Sequences:

>Translated_817_residues
MLNLSSIMKPNEIMKNWIDPEAKAEAERYDNPIPSRTLILTTLEQLDLPQSHAELVDHFDIHDQKSIDALSHRLIAMVRD
GQLSKDGFKFQPIGEQPTFDATVYINNKGFGSAHIDGQNDLLLPERELRLVFNGDRVKVRQTSVDRKGKAWGFITEVTQH
RVKQLIGKLAVHEGEYFLQPSAPNAHQPIPLEKELIEHAQAKVGENLRVAIDDYPTREEFSTGHIIQSMSDKADTEIIIP
QTILEFGLPYEFPEEVVKDAESFKEPSKKDIEGRIDLRDLPLVTIDGEDARDFDDAVYAEKRSGGGYRVVVAIADVSHYV
RLGKPLDDEAQERGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRAGRVMSYEFYPSVMHSKARLTYTQV
GNYFDGQTDAIPDDKNIQKSLNTLFQLYQTLKGLRAKRHAMEFETIETYMTFDELGGIKEILPRTRNEAHKLIEECMLLA
NVAAAEFSLQHDIPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQRVIEATKDRIDAPSIHAVLLRSMMQAYY
GAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLQQKPYPLSGAALDDAGEQFSRTERRADEASRSVTTWLKCHYM
KQHLGEEFIGIISAVTEFGLFVTLKDLYVDGMIHVSQLGDDFFLYDQASQSLVGQNRGQIFGLGDEVKIKVAAVNLDERK
IDFELMQQITHAGRVIRQKAPRSSKTQATEQVFNVPSETTSTQERDTRKKEKSKSKPSSYAKKSAKKSSPASVSKPVKEK
KKVKVKKKKSNAKPKSE
>Mature_817_residues
MLNLSSIMKPNEIMKNWIDPEAKAEAERYDNPIPSRTLILTTLEQLDLPQSHAELVDHFDIHDQKSIDALSHRLIAMVRD
GQLSKDGFKFQPIGEQPTFDATVYINNKGFGSAHIDGQNDLLLPERELRLVFNGDRVKVRQTSVDRKGKAWGFITEVTQH
RVKQLIGKLAVHEGEYFLQPSAPNAHQPIPLEKELIEHAQAKVGENLRVAIDDYPTREEFSTGHIIQSMSDKADTEIIIP
QTILEFGLPYEFPEEVVKDAESFKEPSKKDIEGRIDLRDLPLVTIDGEDARDFDDAVYAEKRSGGGYRVVVAIADVSHYV
RLGKPLDDEAQERGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRAGRVMSYEFYPSVMHSKARLTYTQV
GNYFDGQTDAIPDDKNIQKSLNTLFQLYQTLKGLRAKRHAMEFETIETYMTFDELGGIKEILPRTRNEAHKLIEECMLLA
NVAAAEFSLQHDIPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQRVIEATKDRIDAPSIHAVLLRSMMQAYY
GAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLQQKPYPLSGAALDDAGEQFSRTERRADEASRSVTTWLKCHYM
KQHLGEEFIGIISAVTEFGLFVTLKDLYVDGMIHVSQLGDDFFLYDQASQSLVGQNRGQIFGLGDEVKIKVAAVNLDERK
IDFELMQQITHAGRVIRQKAPRSSKTQATEQVFNVPSETTSTQERDTRKKEKSKSKPSSYAKKSAKKSSPASVSKPVKEK
KKVKVKKKKSNAKPKSE

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=566, Percent_Identity=30.0353356890459, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI190014625, Length=566, Percent_Identity=30.2120141342756, Blast_Score=193, Evalue=7e-49,
Organism=Homo sapiens, GI134288890, Length=417, Percent_Identity=29.7362110311751, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI19115966, Length=617, Percent_Identity=26.418152350081, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI219521928, Length=617, Percent_Identity=26.418152350081, Blast_Score=153, Evalue=7e-37,
Organism=Escherichia coli, GI87082383, Length=748, Percent_Identity=42.379679144385, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1787542, Length=650, Percent_Identity=25.2307692307692, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=443, Percent_Identity=30.2483069977427, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=426, Percent_Identity=30.9859154929577, Blast_Score=158, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324552, Length=507, Percent_Identity=28.5996055226824, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323943, Length=400, Percent_Identity=24.5, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649634, Length=493, Percent_Identity=30.8316430020284, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI19922976, Length=364, Percent_Identity=29.9450549450549, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24654597, Length=364, Percent_Identity=29.9450549450549, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24654592, Length=364, Percent_Identity=29.9450549450549, Blast_Score=139, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 92533; Mature: 92533

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLSSIMKPNEIMKNWIDPEAKAEAERYDNPIPSRTLILTTLEQLDLPQSHAELVDHFD
CCCHHHHCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHCC
IHDQKSIDALSHRLIAMVRDGQLSKDGFKFQPIGEQPTFDATVYINNKGFGSAHIDGQND
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCEEECCCCC
LLLPERELRLVFNGDRVKVRQTSVDRKGKAWGFITEVTQHRVKQLIGKLAVHEGEYFLQP
CCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SAPNAHQPIPLEKELIEHAQAKVGENLRVAIDDYPTREEFSTGHIIQSMSDKADTEIIIP
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHCCCCCCEEECH
QTILEFGLPYEFPEEVVKDAESFKEPSKKDIEGRIDLRDLPLVTIDGEDARDFDDAVYAE
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHH
KRSGGGYRVVVAIADVSHYVRLGKPLDDEAQERGTSVYFPHFVLPMLPEALSNGLCSLNP
HCCCCCEEEEEEEECHHHHHHCCCCCCHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCCC
HVDRLCMVCDLKLSRAGRVMSYEFYPSVMHSKARLTYTQVGNYFDGQTDAIPDDKNIQKS
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHEEHHHHCCCCCCCCCCCCCCHHHHHH
LNTLFQLYQTLKGLRAKRHAMEFETIETYMTFDELGGIKEILPRTRNEAHKLIEECMLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
NVAAAEFSLQHDIPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQRVIEATKD
HHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RIDAPSIHAVLLRSMMQAYYGAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLQQ
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPYPLSGAALDDAGEQFSRTERRADEASRSVTTWLKCHYMKQHLGEEFIGIISAVTEFGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTLKDLYVDGMIHVSQLGDDFFLYDQASQSLVGQNRGQIFGLGDEVKIKVAAVNLDERK
HEEEHHHHHCCCHHHHHCCCCEEEECHHHHHHHCCCCCCEEECCCCEEEEEEEECCCHHH
IDFELMQQITHAGRVIRQKAPRSSKTQATEQVFNVPSETTSTQERDTRKKEKSKSKPSSY
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHH
AKKSAKKSSPASVSKPVKEKKKVKVKKKKSNAKPKSE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLNLSSIMKPNEIMKNWIDPEAKAEAERYDNPIPSRTLILTTLEQLDLPQSHAELVDHFD
CCCHHHHCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHCC
IHDQKSIDALSHRLIAMVRDGQLSKDGFKFQPIGEQPTFDATVYINNKGFGSAHIDGQND
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCEEECCCCC
LLLPERELRLVFNGDRVKVRQTSVDRKGKAWGFITEVTQHRVKQLIGKLAVHEGEYFLQP
CCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SAPNAHQPIPLEKELIEHAQAKVGENLRVAIDDYPTREEFSTGHIIQSMSDKADTEIIIP
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHCCCCCCEEECH
QTILEFGLPYEFPEEVVKDAESFKEPSKKDIEGRIDLRDLPLVTIDGEDARDFDDAVYAE
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHH
KRSGGGYRVVVAIADVSHYVRLGKPLDDEAQERGTSVYFPHFVLPMLPEALSNGLCSLNP
HCCCCCEEEEEEEECHHHHHHCCCCCCHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCCC
HVDRLCMVCDLKLSRAGRVMSYEFYPSVMHSKARLTYTQVGNYFDGQTDAIPDDKNIQKS
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHEEHHHHCCCCCCCCCCCCCCHHHHHH
LNTLFQLYQTLKGLRAKRHAMEFETIETYMTFDELGGIKEILPRTRNEAHKLIEECMLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
NVAAAEFSLQHDIPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQRVIEATKD
HHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RIDAPSIHAVLLRSMMQAYYGAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLQQ
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KPYPLSGAALDDAGEQFSRTERRADEASRSVTTWLKCHYMKQHLGEEFIGIISAVTEFGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVTLKDLYVDGMIHVSQLGDDFFLYDQASQSLVGQNRGQIFGLGDEVKIKVAAVNLDERK
HEEEHHHHHCCCHHHHHCCCCEEEECHHHHHHHCCCCCCEEECCCCEEEEEEEECCCHHH
IDFELMQQITHAGRVIRQKAPRSSKTQATEQVFNVPSETTSTQERDTRKKEKSKSKPSSY
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHH
AKKSAKKSSPASVSKPVKEKKKVKVKKKKSNAKPKSE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]