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The map label for this gene is infC

Identifier: 50086066

GI number: 50086066

Start: 2980636

End: 2981187

Strand: Reverse

Name: infC

Synonym: ACIAD3054

Alternate gene names: 50086066

Gene position: 2981187-2980636 (Counterclockwise)

Preceding gene: 50086067

Following gene: 50086064

Centisome position: 82.84

GC content: 40.76

Gene sequence:

>552_bases
ATTAAACAGCCTGACCGTAACCAACAACAAGGTGCAAAGAGTAACCGTCCTGCGATTAATGACGAGATTCGTTCTAAAGA
AGTGCGTCTCGTTGGTGCAGATGGGGAACAAAAAGGAATCGTTTCATTAAATGAAGCGTTGCGTGCTGCAGAAGAAGTTG
AACTTGATTTAGTCGAGATCGTTGCGAATGCAGAACCACCTGTTTGTAAAATCATGGATTACAACAAGCACTTGTTTGAT
TTGAAGCAAAAGCAAAAAGATGCGAAGAAAAAACAGCATCAAGTGCAAGTGAAAGAAATCAAACTGCGTCCCGCAACGGA
TGTAGGTGATTATCAGGTCAAACTTCGTGCGATTTTAAAGTTCCTTGAAGAAGGTAACAAAGTTAAAATCACATTACGTT
TCCGTGGTCGTGAAATGGCACATCAACAGTTGGGTCTTGCTCAGTTACAAAAAATTGAAGCAGACGTGACAGAGTATGGT
GTTGTTGAACAAGCACCTAAAATGGAAGGCCGTCAAATGGGAATGTTACTTGGACCGAAAAAGAAAAAGTAA

Upstream 100 bases:

>100_bases
GCTCAGGAAAAAATTTAGGTACTATGTCAATCGATGCATTCGTTGACTTAGTGAAATCTGCCGTTGCCGAACGTGGCCGG
TACATTGTGGAGTAAGAGAG

Downstream 100 bases:

>100_bases
TTGACCATTTCTAAAAAACGCAGCGTAACAGCTGCGTTTTTTTATACTTCCATTTTATAACTCAGAAAGAAAAAAGGAGT
GCATATTGGCACTCCTTTTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKQPDRNQQQGAKSNRPAINDEIRSKEVRLVGADGEQKGIVSLNEALRAAEEVELDLVEIVANAEPPVCKIMDYNKHLFD
LKQKQKDAKKKQHQVQVKEIKLRPATDVGDYQVKLRAILKFLEEGNKVKITLRFRGREMAHQQLGLAQLQKIEADVTEYG
VVEQAPKMEGRQMGMLLGPKKKK

Sequences:

>Translated_183_residues
MKQPDRNQQQGAKSNRPAINDEIRSKEVRLVGADGEQKGIVSLNEALRAAEEVELDLVEIVANAEPPVCKIMDYNKHLFD
LKQKQKDAKKKQHQVQVKEIKLRPATDVGDYQVKLRAILKFLEEGNKVKITLRFRGREMAHQQLGLAQLQKIEADVTEYG
VVEQAPKMEGRQMGMLLGPKKKK
>Mature_183_residues
MKQPDRNQQQGAKSNRPAINDEIRSKEVRLVGADGEQKGIVSLNEALRAAEEVELDLVEIVANAEPPVCKIMDYNKHLFD
LKQKQKDAKKKQHQVQVKEIKLRPATDVGDYQVKLRAILKFLEEGNKVKITLRFRGREMAHQQLGLAQLQKIEADVTEYG
VVEQAPKMEGRQMGMLLGPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=175, Percent_Identity=62.8571428571429, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_ACIAD (Q6F861)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047576.1
- ProteinModelPortal:   Q6F861
- STRING:   Q6F861
- GeneID:   2877817
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3054
- NMPDR:   fig|62977.3.peg.2769
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   KQMKFRL
- PhylomeDB:   Q6F861
- ProtClustDB:   PRK00028
- BioCyc:   ASP62977:ACIAD3054-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20792; Mature: 20792

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPDRNQQQGAKSNRPAINDEIRSKEVRLVGADGEQKGIVSLNEALRAAEEVELDLVEI
CCCCCCCHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
VANAEPPVCKIMDYNKHLFDLKQKQKDAKKKQHQVQVKEIKLRPATDVGDYQVKLRAILK
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEHHHEEECCCCCCCHHHHHHHHHHH
FLEEGNKVKITLRFRGREMAHQQLGLAQLQKIEADVTEYGVVEQAPKMEGRQMGMLLGPK
HHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHCCCCCCCC
KKK
CCC
>Mature Secondary Structure
MKQPDRNQQQGAKSNRPAINDEIRSKEVRLVGADGEQKGIVSLNEALRAAEEVELDLVEI
CCCCCCCHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
VANAEPPVCKIMDYNKHLFDLKQKQKDAKKKQHQVQVKEIKLRPATDVGDYQVKLRAILK
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEHHHEEECCCCCCCHHHHHHHHHHH
FLEEGNKVKITLRFRGREMAHQQLGLAQLQKIEADVTEYGVVEQAPKMEGRQMGMLLGPK
HHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHCCCCCCCC
KKK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA