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The map label for this gene is yfcG [H]

Identifier: 50086064

GI number: 50086064

Start: 2979141

End: 2979761

Strand: Reverse

Name: yfcG [H]

Synonym: ACIAD3051

Alternate gene names: 50086064

Gene position: 2979761-2979141 (Counterclockwise)

Preceding gene: 50086066

Following gene: 50086063

Centisome position: 82.8

GC content: 41.22

Gene sequence:

>621_bases
ATGATAGACCTATATTATTGGGGGACACCCAATGGACATAAGATTACAATTGCCCTTGAAGAAATGGGGCTGGAATACAC
CATCTATCCCATCAATATTTTAGAAAATGACCAGTTTCAACCTGACTTTTTAAGAATTTCGCCGAATAACAAAATTCCTG
CAATTGTAGATCAGAATGGTCCGCGTGATCAGCCGATTTCAATTTTTGAGTCAGGTGCAATTTTGCAGTATCTCGGACGT
AAAACAGGCTTATTTTATCCTATAGATGAGCAAGAACGGGTTGAGGTAGAGCAATGGTTGATGTGGCAAATGGGCGGTTT
TGGCCCTATGCTGGGTCAAAATCATCATTTTGGGCGCTTTGCCAAAGAAAAAATTCCCTATGCAATTGATCGTTATGTCA
ACGAAACCAAACGTCTGTATAAAGTGCTCAATACGCAGTTGATTGGTCAGAAGTTTGTTGCTGGTGAGTATTCGATTGCG
GACATGGCGATCCTACCTTGGATATTACGGCATGAATGGCAGTCGGTTGATCTCAATGACTATCCCTATGTTCAGGATTA
TGTTGAGCGTCTGACCGCACGTCCAGCTATACAAAAAGCGCTTTCAATTCAAATCATTTAA

Upstream 100 bases:

>100_bases
TTAGAATAAATTGTCTTTAATACTTTTGATCGAAGATTAAAATCATGTATAAAAGTATAAAAAGACGCCAAGAAACAAAA
TTAGGATAAGAAGGTATTTC

Downstream 100 bases:

>100_bases
TTTTGCTTAAAAGCAAATTCGATCAGCATAAGATGGACATATTGGATATCAGACTTAAAACTGAGATATTAGCCAGATAA
TGTAATCCATGCGACAACGT

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIDLYYWGTPNGHKITIALEEMGLEYTIYPINILENDQFQPDFLRISPNNKIPAIVDQNGPRDQPISIFESGAILQYLGR
KTGLFYPIDEQERVEVEQWLMWQMGGFGPMLGQNHHFGRFAKEKIPYAIDRYVNETKRLYKVLNTQLIGQKFVAGEYSIA
DMAILPWILRHEWQSVDLNDYPYVQDYVERLTARPAIQKALSIQII

Sequences:

>Translated_206_residues
MIDLYYWGTPNGHKITIALEEMGLEYTIYPINILENDQFQPDFLRISPNNKIPAIVDQNGPRDQPISIFESGAILQYLGR
KTGLFYPIDEQERVEVEQWLMWQMGGFGPMLGQNHHFGRFAKEKIPYAIDRYVNETKRLYKVLNTQLIGQKFVAGEYSIA
DMAILPWILRHEWQSVDLNDYPYVQDYVERLTARPAIQKALSIQII
>Mature_206_residues
MIDLYYWGTPNGHKITIALEEMGLEYTIYPINILENDQFQPDFLRISPNNKIPAIVDQNGPRDQPISIFESGAILQYLGR
KTGLFYPIDEQERVEVEQWLMWQMGGFGPMLGQNHHFGRFAKEKIPYAIDRYVNETKRLYKVLNTQLIGQKFVAGEYSIA
DMAILPWILRHEWQSVDLNDYPYVQDYVERLTARPAIQKALSIQII

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=55.3921568627451, Blast_Score=219, Evalue=8e-59,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=42.9906542056075, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI87081789, Length=174, Percent_Identity=27.0114942528736, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=28.2051282051282, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17933730, Length=198, Percent_Identity=35.3535353535354, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571670, Length=179, Percent_Identity=36.3128491620112, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45549270, Length=194, Percent_Identity=31.9587628865979, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864592, Length=195, Percent_Identity=30.2564102564103, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864598, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646251, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864596, Length=196, Percent_Identity=29.0816326530612, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864594, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725204, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17737923, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646249, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221378983, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646259, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24041; Mature: 24041

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWGTPNGHKITIALEEMGLEYTIYPINILENDQFQPDFLRISPNNKIPAIVDQNG
CEEEEEECCCCCCEEEEEEHHCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCEEECCCC
PRDQPISIFESGAILQYLGRKTGLFYPIDEQERVEVEQWLMWQMGGFGPMLGQNHHFGRF
CCCCCCHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AKEKIPYAIDRYVNETKRLYKVLNTQLIGQKFVAGEYSIADMAILPWILRHEWQSVDLND
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
YPYVQDYVERLTARPAIQKALSIQII
CCHHHHHHHHHHCCHHHHHHEEEECC
>Mature Secondary Structure
MIDLYYWGTPNGHKITIALEEMGLEYTIYPINILENDQFQPDFLRISPNNKIPAIVDQNG
CEEEEEECCCCCCEEEEEEHHCCCEEEEEEEEEECCCCCCCCEEEECCCCCCCEEECCCC
PRDQPISIFESGAILQYLGRKTGLFYPIDEQERVEVEQWLMWQMGGFGPMLGQNHHFGRF
CCCCCCHHHCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AKEKIPYAIDRYVNETKRLYKVLNTQLIGQKFVAGEYSIADMAILPWILRHEWQSVDLND
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
YPYVQDYVERLTARPAIQKALSIQII
CCHHHHHHHHHHCCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]