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The map label for this gene is entC [H]

Identifier: 50085832

GI number: 50085832

Start: 2722849

End: 2724036

Strand: Reverse

Name: entC [H]

Synonym: ACIAD2776

Alternate gene names: 50085832

Gene position: 2724036-2722849 (Counterclockwise)

Preceding gene: 50085833

Following gene: 50085831

Centisome position: 75.7

GC content: 35.77

Gene sequence:

>1188_bases
GTGTATTACAAGGGGAATGGCTTCATGAATGATATGAATCTCTCAATTGATCATGCAATTGAACTGAATATTAACCTAGA
ATCTTCTTGTTTTTTAACTAAAGATTATCGTTTATTAGCATCAGATTTAGCTGAAGTAGTAAAATTAGCTGCTTGCGATT
ATGAAAAATTAAGTCAAACCATTACAGATAGTTTTCAGAAATTAAAAAAAGATCCAAATGCAAATCCAATTTTGGTTGGT
GCAATTCCATTCGATACAACACAAGCATCGTCTCTCAATATTTATCGGAATCATCGTAAACAAAGACAATTGGTGATTTC
ATCTAAAATAACTCATTCGCCATTATCTATTTCAAATCAAAAACCTTTGATTAAACAAAAAGATTTTGCGCATGCCATTG
ATATTGCAATTGATCAGTTTAGGTGTGATCAATTGGAAAAAGTGGTTTTGTCACAGGCTGTGGATTTTGAACTTTCACAG
TCACAAAATCCTTTTGATTTGGTTGATACATTAGCTAAAGAAAATCCACATGCATTTAGTTTTGCTATTCCAGTTGAAGA
CAATGCTTACCTTCTGGGTGCAAGTCCAGAGTTACTGATTTCAAAAAATGATCTGACTGTTCGTAGTAATCCTTTAGCAG
GCTCTCGTCCTTTAAGTGAGGATGAAAATATAAATCAGTCACGTATTCATGAATTGTATGCATCAGAAAAAGATCTTAAT
GAGCATCAAATTGTGGTGGACAGTGTCTTAGAAAATTTAAAGCCATTTTGCCAAAAATTAAAGGTTTTAGAGAAACCTGA
AATTTTAAAAACGGCCACGATGCTTCATCTTTCGACCGTATTTGATGGTCAGTTGAAAAAGCAGTCTGACAATGCGTTGC
AGTTGGCATTGGCTTTACATCCTACACCTGCAATCTGTGGTTCACCTACCGAGCCTGCAAAACAGTTTATTTTAGAACAT
GAGGGTTACGACCGTCATTATTTTGCTGGTTTGGTGGGATGGATGGATGCCCAAGGTAATGGCGAATGGGCTGTCACTAT
TCGTTGCGGTTTACTCAATGATAAAAAAATTCGTTTATATGCTGGTGCTGGAATTGTGATGGGATCACAAGCTGAACTTG
AATGGAGTGAAACTGAAGTCAAAATGCAAACTCTACTAAAAACCCTAAGCGCAACTTTTCATTCCTGA

Upstream 100 bases:

>100_bases
GGATATTTTCTATTAAATGTTAATGATTATCAATATTATTATTGTTAATGCAATTGCATGCACTAGAAATTTTAGTTGTT
TATTGACTGGGAATTAACAC

Downstream 100 bases:

>100_bases
TGAAAACAAATTCTATATTTGGCGCCAATAGAGCATGAAAACCAAATCAAAGACATATTTTTGAAAACAGATTAACGATA
TATAGGCAACACTATGACCA

Product: isochorismate synthetase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQTITDSFQKLKKDPNANPILVG
AIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQ
SQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLN
EHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEH
EGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS

Sequences:

>Translated_395_residues
MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQTITDSFQKLKKDPNANPILVG
AIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQ
SQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLN
EHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEH
EGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS
>Mature_395_residues
MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQTITDSFQKLKKDPNANPILVG
AIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQ
SQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLN
EHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEH
EGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=336, Percent_Identity=39.2857142857143, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082077, Length=276, Percent_Identity=30.4347826086957, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787518, Length=281, Percent_Identity=28.8256227758007, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788114, Length=239, Percent_Identity=28.4518828451883, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=228, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 44156; Mature: 44156

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQT
CEECCCCCCCCCCEEEEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
ITDSFQKLKKDPNANPILVGAIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQ
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHEEHECCCCCCCCCCCCC
KPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCCCCCEEE
FAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLN
EEEECCCCCEEEECCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEEEC
PTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLY
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCEEEEEEEECCCCCEEEEE
AGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS
ECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQT
CEECCCCCCCCCCEEEEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHH
ITDSFQKLKKDPNANPILVGAIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQ
HHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHEEHECCCCCCCCCCCCC
KPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHCCCCCEEE
FAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLN
EEEECCCCCEEEECCCCEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
EHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCCEEEEEEEEC
PTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLY
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCCEEEEEEEECCCCCEEEEE
AGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS
ECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]