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The map label for this gene is aroQ

Identifier: 50084891

GI number: 50084891

Start: 1746272

End: 1746721

Strand: Reverse

Name: aroQ

Synonym: ACIAD1738

Alternate gene names: 50084891

Gene position: 1746721-1746272 (Counterclockwise)

Preceding gene: 50084892

Following gene: 50084890

Centisome position: 48.54

GC content: 39.56

Gene sequence:

>450_bases
ATGAGTTCAACCATTTTGGTGATTCACGGACCGAATTTGAATCTTTTAGGAAAAAGAGAACCAGAGGTATATGGTTATCT
CAGTCTTGATGATATCAATCAACAGCTCAAAACCCAAGCTCAAGCATCAAATATCTCATTAGAAACTTTCCAAAGTAATT
GGGAAGGCGCGATCGTTGATCGTATCCATCAGGCACAAATTGATGGTATTCAATTTATTCTCATCAATCCAGCAGCATTA
ACCCATACATCTGTTGCGGTTAGGGATGCATTGCTTGGCGTTGCTATTCCCTTTATTGAAGTTCATTTATCGAACGTTCA
CGCTCGTGAAGCTTTTAGACATCACTCATATTTGTCCGATAAAGCGGTTGGCGTAATTTGCGGTTTCGGTGCAAAGGGTT
ATCACTTTGCACTGGATTATGCCATCCAAAAAATTCAACCATCTACTTAA

Upstream 100 bases:

>100_bases
AAGCAATTTGCACAAGAAATGTAGAAATATATGCCATAATAAGCAAACTTTGCAGGTAATTTGCAAAGAAATTTGCATTT
AAGAAATTGGAGCACGTTGA

Downstream 100 bases:

>100_bases
TTCAACATGATTTAGGAACATTCACCTATGGATATTCGCAAAATTAAGAAACTCATCGACTTGATGATTGAATCTGACTT
ACAAGCGATTGAGGTTAAAG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSSTILVIHGPNLNLLGKREPEVYGYLSLDDINQQLKTQAQASNISLETFQSNWEGAIVDRIHQAQIDGIQFILINPAAL
THTSVAVRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAVGVICGFGAKGYHFALDYAIQKIQPST

Sequences:

>Translated_149_residues
MSSTILVIHGPNLNLLGKREPEVYGYLSLDDINQQLKTQAQASNISLETFQSNWEGAIVDRIHQAQIDGIQFILINPAAL
THTSVAVRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAVGVICGFGAKGYHFALDYAIQKIQPST
>Mature_148_residues
SSTILVIHGPNLNLLGKREPEVYGYLSLDDINQQLKTQAQASNISLETFQSNWEGAIVDRIHQAQIDGIQFILINPAALT
HTSVAVRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAVGVICGFGAKGYHFALDYAIQKIQPST

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_ACIAD (Q6FBI3)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046401.1
- ProteinModelPortal:   Q6FBI3
- SMR:   Q6FBI3
- STRING:   Q6FBI3
- GeneID:   2878793
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1738
- NMPDR:   fig|62977.3.peg.1663
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   ASP62977:ACIAD1738-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16390; Mature: 16259

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 102-102 BINDING 76-76 BINDING 82-82 BINDING 89-89 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTILVIHGPNLNLLGKREPEVYGYLSLDDINQQLKTQAQASNISLETFQSNWEGAIVD
CCCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
RIHQAQIDGIQFILINPAALTHTSVAVRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSD
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCC
KAVGVICGFGAKGYHFALDYAIQKIQPST
CCEEEEECCCCCCEEEHHHHHHHHCCCCC
>Mature Secondary Structure 
SSTILVIHGPNLNLLGKREPEVYGYLSLDDINQQLKTQAQASNISLETFQSNWEGAIVD
CCEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHH
RIHQAQIDGIQFILINPAALTHTSVAVRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSD
HHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCC
KAVGVICGFGAKGYHFALDYAIQKIQPST
CCEEEEECCCCCCEEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA