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The map label for this gene is dcaK [H]

Identifier: 50084849

GI number: 50084849

Start: 1699220

End: 1700527

Strand: Direct

Name: dcaK [H]

Synonym: ACIAD1694

Alternate gene names: 50084849

Gene position: 1699220-1700527 (Clockwise)

Preceding gene: 50084848

Following gene: 50084850

Centisome position: 47.22

GC content: 41.06

Gene sequence:

>1308_bases
ATGCATATATTGTCTGAGGATATAGACATGACAACAGATTCAATTACAACAAGCCAGCCTAATCAAGCCATACAAACGCC
TAAAAAGATTTGGATTACTGCTTTTATATTTGCATTTTTAGCTTTGCTATGTGACGGTGCCGATTTGGGATTTTTGGCAT
TGAGCTTGACCAGTTTGAAAAGTGAATTTCATCTCACTGGATTACAAGCAGGTACTTTAGGAAGTTTAACTCTTTTTGGG
TCTGCTATTGGTGGCCTATTTGGTGGGTGGGCGTGTGATCGTTTTGGTCGCGTGCGGATTATTGTGTTTTTTATTGCGTA
TTCATCAATTCTCACTTGTGCCTTGGGTTTTACTCACTCATTTGAACAATTTGCGATTGTGCGGGTCTTTGGTTCGATGG
GGCTTGGTGCGCTTTACATTGCGTGTAACGTGTTGATGTCGGAGATGGTTCCGACCAAGCATCGTACGACAGTACTTGCT
ACCTTGATGACAGGATATACCTTGGGTTCGTTGCTGGCGACCTTGCTGGCTGGACATATCATTCCCGAGCATGGCTGGCG
TTATTTGTACTGGTTAGCCATTGTACCAGTCGTCCTTTCATTTTTTATGCACTATATGGTTCCAGAACCAGAATCATGGA
AAAAATCTCGTCAAATTCGTGCGCAGCAAGCAACAGGCGGTATGAAAGAGGTTAAACGCGAAAATCCGTATCGTGAAATC
TTTAAAGAAAAGAAACATGGCATTATGTTTCTGCTTTGGGTAGTGAGTACTGGAGCATTACAATTTGGTTACTACGGTGT
AAGTAACTGGTTACCTGCTTATTTAGAATCTGAGCTTGGGATTAAATTCAAAGAAATGGCAATGTATATGGTGGGAACAT
TCATCATTATGATTTTTGCCAAAATCATTGCAGGTATGATTGCAGACAAACTTGGTCGTCGGGCTGTATTTGCCTTTGGT
ACCATCGGGACTGCATTATTTATTCCCGTGATTGTGTACCTGAATACTCCTGCCAATATTTTATGGATGATGCTATTTTT
TGGCTTCCTTTACGGTATTCCATATGCCATTAATGCGACCTATATGACAGAAAGTTTTCCAACATCAATTCGTGGTTCCG
CTGTTGGTGGAGCTTACAACGTGGGTAAAGTTCTTTCTATTTTTTCTCCACTTACCATTGGGTATTTATCACAAAGTGGC
TCTATTGGTCTAGGTTTGCTGGTTATGGCTGCTGCTTACTTTATTTGTGGTGTGATCCCGCTTTTATTTATCAAGGATCG
ACTTTATAACCCCCAAAAAGCGGATTAA

Upstream 100 bases:

>100_bases
GGTACGACCCAAGTTCAGCAAATTATTATTGCCAAAAATATGATTAAGGAAGTGACGTCCTAAAGCCTTATTTTACTTAA
CATGAGGCAGAGGATGCCTC

Downstream 100 bases:

>100_bases
TAACGAGTCATTCTGATACACATGATCAGTCTTCACATCTCAAAATTATTAGATTTTAGAAAGTACAACAAATTTAATTC
TCAATGATCGGTGACAGGAT

Product: dicarboxylic acid major facilitator family transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MHILSEDIDMTTDSITTSQPNQAIQTPKKIWITAFIFAFLALLCDGADLGFLALSLTSLKSEFHLTGLQAGTLGSLTLFG
SAIGGLFGGWACDRFGRVRIIVFFIAYSSILTCALGFTHSFEQFAIVRVFGSMGLGALYIACNVLMSEMVPTKHRTTVLA
TLMTGYTLGSLLATLLAGHIIPEHGWRYLYWLAIVPVVLSFFMHYMVPEPESWKKSRQIRAQQATGGMKEVKRENPYREI
FKEKKHGIMFLLWVVSTGALQFGYYGVSNWLPAYLESELGIKFKEMAMYMVGTFIIMIFAKIIAGMIADKLGRRAVFAFG
TIGTALFIPVIVYLNTPANILWMMLFFGFLYGIPYAINATYMTESFPTSIRGSAVGGAYNVGKVLSIFSPLTIGYLSQSG
SIGLGLLVMAAAYFICGVIPLLFIKDRLYNPQKAD

Sequences:

>Translated_435_residues
MHILSEDIDMTTDSITTSQPNQAIQTPKKIWITAFIFAFLALLCDGADLGFLALSLTSLKSEFHLTGLQAGTLGSLTLFG
SAIGGLFGGWACDRFGRVRIIVFFIAYSSILTCALGFTHSFEQFAIVRVFGSMGLGALYIACNVLMSEMVPTKHRTTVLA
TLMTGYTLGSLLATLLAGHIIPEHGWRYLYWLAIVPVVLSFFMHYMVPEPESWKKSRQIRAQQATGGMKEVKRENPYREI
FKEKKHGIMFLLWVVSTGALQFGYYGVSNWLPAYLESELGIKFKEMAMYMVGTFIIMIFAKIIAGMIADKLGRRAVFAFG
TIGTALFIPVIVYLNTPANILWMMLFFGFLYGIPYAINATYMTESFPTSIRGSAVGGAYNVGKVLSIFSPLTIGYLSQSG
SIGLGLLVMAAAYFICGVIPLLFIKDRLYNPQKAD
>Mature_435_residues
MHILSEDIDMTTDSITTSQPNQAIQTPKKIWITAFIFAFLALLCDGADLGFLALSLTSLKSEFHLTGLQAGTLGSLTLFG
SAIGGLFGGWACDRFGRVRIIVFFIAYSSILTCALGFTHSFEQFAIVRVFGSMGLGALYIACNVLMSEMVPTKHRTTVLA
TLMTGYTLGSLLATLLAGHIIPEHGWRYLYWLAIVPVVLSFFMHYMVPEPESWKKSRQIRAQQATGGMKEVKRENPYREI
FKEKKHGIMFLLWVVSTGALQFGYYGVSNWLPAYLESELGIKFKEMAMYMVGTFIIMIFAKIIAGMIADKLGRRAVFAFG
TIGTALFIPVIVYLNTPANILWMMLFFGFLYGIPYAINATYMTESFPTSIRGSAVGGAYNVGKVLSIFSPLTIGYLSQSG
SIGLGLLVMAAAYFICGVIPLLFIKDRLYNPQKAD

Specific function: Probable uptake of muconate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=419, Percent_Identity=21.4797136038186, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI24308167, Length=427, Percent_Identity=21.3114754098361, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082404, Length=400, Percent_Identity=22, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082231, Length=417, Percent_Identity=24.7002398081535, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790550, Length=376, Percent_Identity=21.5425531914894, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081723, Length=398, Percent_Identity=24.8743718592965, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790463, Length=345, Percent_Identity=23.768115942029, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786229, Length=387, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=417, Percent_Identity=21.1031175059952, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082159, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788068, Length=383, Percent_Identity=23.7597911227154, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789207, Length=336, Percent_Identity=23.8095238095238, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534558, Length=379, Percent_Identity=24.2744063324538, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=295, Percent_Identity=24.7457627118644, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221330907, Length=352, Percent_Identity=25.2840909090909, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584153, Length=252, Percent_Identity=23.015873015873, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48025; Mature: 48025

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]