Click here to switch to the map view.

The map label for this gene is dcaI [H]

Identifier: 50084850

GI number: 50084850

Start: 1700817

End: 1701488

Strand: Direct

Name: dcaI [H]

Synonym: ACIAD1695

Alternate gene names: 50084850

Gene position: 1700817-1701488 (Clockwise)

Preceding gene: 50084849

Following gene: 50084851

Centisome position: 47.26

GC content: 39.73

Gene sequence:

>672_bases
ATGATTAATAAAATCATTAATGATATTGAGCCCATTTTAAAATCGATTCCAGATGGTTCAACGATTATGACAAGTGGTTT
TGGTACGACAGGTCAACCTGAGGCACTACTTGAAGCATTAATTGATTTCGCTCCAAAAGAGTTAACTATTATCAATAATA
ATGCTTCATCTGGCCCGAATGGTTTGACTCAGCTTTTCACTGCTGGATTGGTCAAAAAGCTCATTTGCTCGTATCCAAAA
TCAATCAGTTCGACTGTTTTTCCAGATTTATATCGTGCGGGAAAAATTGAACTTGAACTGGTTCCTCAGGGAAATCTTGC
ATGTCGTATTCAAGCAGCAGGTGCTGGTCTGGGAGCGGTATTTACCCCCACAGGCTACGGGACCAAAATTGCTGAAGGCA
AAGAAACGCGCATTATTAACGGTAAAAATTATGTACTTGAATATCCACTTGAAGCCGATTATGCATTCATTTATGCAGAT
AAGGCAGATCGCTGGGGGAATTTAACTTATCGTAAAGCCGCCAGAAATTTTGGTCCGATTATGGCCAAAGCTGCAAAAAC
AACAATTGCTCAAGTCAATCAAACTGTTGAATTGGGTGATCTTGATCCCGAATGCATTATTACACCCGGGATATTTGTAC
AGCATGTGGTGCGATTAGGAGATATAAAATGA

Upstream 100 bases:

>100_bases
TGAGCCCAACATTGTTTATTAAAGACAGGTTATACGCCTCTAGAAAGCAGATGAATTCAAATGTTTAAGAAGTGTATAAA
TGCAAAAGGAATGAATGCTT

Downstream 100 bases:

>100_bases
CGATTCAGAAAAGAAGTCGAGAAGATATCGCAATCATGATAGCAAAGGATATTCCTGATGGTTCGTATGTCAATCTTGGA
ATTGGATTACCAACCCATGT

Product: acyl-CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MINKIINDIEPILKSIPDGSTIMTSGFGTTGQPEALLEALIDFAPKELTIINNNASSGPNGLTQLFTAGLVKKLICSYPK
SISSTVFPDLYRAGKIELELVPQGNLACRIQAAGAGLGAVFTPTGYGTKIAEGKETRIINGKNYVLEYPLEADYAFIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIAQVNQTVELGDLDPECIITPGIFVQHVVRLGDIK

Sequences:

>Translated_223_residues
MINKIINDIEPILKSIPDGSTIMTSGFGTTGQPEALLEALIDFAPKELTIINNNASSGPNGLTQLFTAGLVKKLICSYPK
SISSTVFPDLYRAGKIELELVPQGNLACRIQAAGAGLGAVFTPTGYGTKIAEGKETRIINGKNYVLEYPLEADYAFIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIAQVNQTVELGDLDPECIITPGIFVQHVVRLGDIK
>Mature_223_residues
MINKIINDIEPILKSIPDGSTIMTSGFGTTGQPEALLEALIDFAPKELTIINNNASSGPNGLTQLFTAGLVKKLICSYPK
SISSTVFPDLYRAGKIELELVPQGNLACRIQAAGAGLGAVFTPTGYGTKIAEGKETRIINGKNYVLEYPLEADYAFIYAD
KADRWGNLTYRKAARNFGPIMAKAAKTTIAQVNQTVELGDLDPECIITPGIFVQHVVRLGDIK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=233, Percent_Identity=39.4849785407725, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=39.9141630901288, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1788551, Length=203, Percent_Identity=41.871921182266, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=40.5063291139241, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21358325, Length=221, Percent_Identity=39.3665158371041, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24655794, Length=224, Percent_Identity=38.8392857142857, Blast_Score=149, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24007; Mature: 24007

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKIINDIEPILKSIPDGSTIMTSGFGTTGQPEALLEALIDFAPKELTIINNNASSGPN
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLTQLFTAGLVKKLICSYPKSISSTVFPDLYRAGKIELELVPQGNLACRIQAAGAGLGAV
HHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGYGTKIAEGKETRIINGKNYVLEYPLEADYAFIYADKADRWGNLTYRKAARNFGPI
ECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCHH
MAKAAKTTIAQVNQTVELGDLDPECIITPGIFVQHVVRLGDIK
HHHHHHHHHHHHHCEEEECCCCCCEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure
MINKIINDIEPILKSIPDGSTIMTSGFGTTGQPEALLEALIDFAPKELTIINNNASSGPN
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLTQLFTAGLVKKLICSYPKSISSTVFPDLYRAGKIELELVPQGNLACRIQAAGAGLGAV
HHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHCCCEEEEEECCCCEEEEEEECCCCCCEE
FTPTGYGTKIAEGKETRIINGKNYVLEYPLEADYAFIYADKADRWGNLTYRKAARNFGPI
ECCCCCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCHH
MAKAAKTTIAQVNQTVELGDLDPECIITPGIFVQHVVRLGDIK
HHHHHHHHHHHHHCEEEECCCCCCEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]